Autophagosomes and Endolysosomes: From Fundamental Mechanisms to Disease Implications

June 25-28, 2025 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers: Christina Towers, Rupert Beale and Leon O. Murphy

  In Person
  On Demand

June 25-28, 2025 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers: Christina Towers, Rupert Beale and Leon O. Murphy

Available Formats:   = In Person     = On Demand
Wednesday, June 25, 2025

Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Thursday, June 26, 2025

Breakfast
7:00–8:00 AM
Welcome and Keynote Address
8:00–9:00 AM
Anne Simonsen, University of Oslo
Intracellular Membrane Trafficking Through Endolysosomes and Autophagy
Intersections of Endolysosomes and Autophagy
9:00–11:15 AM
Marja Jäättelä, Danish Cancer Society Research Center
Targeting Lysosomal Ion and Lipid Homeostasis in Cancer Treatment
Claudine Kraft, University of Freiburg
Molecular Mechanisms in Autophagy
Rupert Beale, The Francis Crick Institute
Non-Canonical Autophagy Mechanisms
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
Poster Viewing
1:00–10:00 PM
Workshop 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Biophysics and Biochemistry of Autophagy
5:00–7:00 PM
Sascha Martens, University of Vienna
Mechanisms of Cargo Selection and Autophagosome Biogenesis
James H. Hurley, University of California, Berkeley
Mechanisms of Autophagy Initiation
Phyllis I. Hanson, University of Michigan
ESCRT, Endolysosomes and Membrane Trafficking
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Friday, June 27, 2025

Breakfast
7:00–8:00 AM
Disease Relevance and Therapeutic Opportunities: Oncology and Metabolism
8:00–11:00 AM
Christina Towers, The Salk Institute for Biological Studies
Targeting Autophagy in Cancer
Rushika M. Perera, University of California, San Francisco
Lysosomes in Cancer
Noor Gammoh, The University of Edinburgh
Lysosome ATPases in Cancer
Chiara Di Malta, Telethon Institute of Genetics and Medicine
TFEB in Metabolic Growth Disorders
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Disease Relevance and Therapeutic Opportunities: Neurodegeneration
5:00–7:00 PM
Yvette C. Wong, Northwestern University
Inter-Organelle Lysosome Contact Sites in Health and Neurodegeneration
Beat Nyfeler, Novartis Institutes for BioMedical Research
Identification of Entry Points for Autophagy-Mediated Targeted Protein and Organelle Degradation using an Induced-Proximity Screen
Juan S. Bonifacino, National Institutes of Health
Endolysosomes and Neurodegeneration
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Saturday, June 28, 2025

Breakfast
7:00–8:00 AM
Disease Relevance and Therapeutic Opportunities: Infection and Immunity
8:00–11:00 AM
Maximiliano Gutierrez, Francis Crick Institute
Xenophagy: Implications for Tuberculosis
Leon O. Murphy, Casma Therapeutics
Reprograming Autophagy to Treat Disease
James Phelan, NCI, National Institutes of Health
The Role of the Autophagy Machinery in Immunity
Nicola Jones, University of Toronto
The Role of Autophagy in Helicobacter Pylori-Mediated Gastrointestinal Disease
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Workshop 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
What Don't We Know About the Autophagy Pathway
5:00–6:45 PM
Herbert (Skip) W. Virgin, Washington University School of Medicine
Intersections Between Autophagy and Endolysosomes: Where the Field has Been and Where is it Going?
Ana Maria Cuervo, Albert Einstein College of Medicine
Chaperone Mediated Autophagy: Where the Field has Been and Where is it Going?
Noboru Mizushima, University of Tokyo
Autophagy Mechanisms: Where the Field has Been and Where is it Going?
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Sunday, June 29, 2025

Departure
12:00–11:59 PM

Subscribe for Updates