Joint with: Neural-Immune Interactions: A Systems-Wide Perspective on Whole Organism Physiology
Neurodegeneration: Linking Cellular Pathways to Therapeutic Strategies

June 8-11, 2025 | Whistler Conference Centre, Whistler, BC, Canada
Scientific Organizers: Michael Ward, Erika L Holzbaur and Sarah L. DeVos

  In Person
  On Demand

June 8-11, 2025 | Whistler Conference Centre, Whistler, BC, Canada
Scientific Organizers: Michael Ward, Erika L Holzbaur and Sarah L. DeVos

Available Formats:   = In Person     = On Demand
Sunday, June 8, 2025

Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Monday, June 9, 2025

Breakfast
7:00–8:00 AM
Welcome and Keynote Session (Joint)
8:00–9:00 AM
Catherine G. Dulac, Harvard University
Neural-Immune and Regulation of Whole-Body Physiology in Health and Disease
Speaker to be Announced
Cell Biology of Neuroinflammation Within Diseased Brain Circuits (Joint)
9:00–11:15 AM
Veronique Miron, University of Toronto
Immune Regulation of Remyelination in Multiple Sclerosis
Timothy Hammond, Sanofi
Therapeutic Targeting of Microglial Inflammatory Responses within Diseased Brain Circuits
Beth Stevens, Boston Children's Hospital, Harvard Medical School
Lysosome Dysfunction Driving Neuroinflammation
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
Poster Viewing
1:00–10:00 PM
Workshop 1: The Digital Era in Neurodegeneration and Neuroinflammation (Joint)
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Genetics and Genomics in Neurodegeneration
5:00–7:00 PM
Jonathan S. Weissman, Whitehead Institute, HHMI, and MIT
Development of Epigenetic Modifiers for Discovery Research and Neurodegenerative Disease Therapies
Juliana Acosta-Uribe, University of California, Santa Barbara
Ancestral Diversity in Neurodegenerative Disease Genomics
Alison Goate, Icahn School of Medicine at Mount Sinai
Genetics and Genomics of Alzheimer’s Disease
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Tuesday, June 10, 2025

Breakfast
7:00–8:00 AM
Mechanisms of Aging in Neuroinflammation and Neurodegeneration (Joint)
8:00–11:00 AM
Robin Franklin, Altos Labs
The Impact of Aging on Remyelination Potential in the Diseased Brain
Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne
Role of cGAS/Sting in Neurodegenerative Diseases
Judith Frydman, Stanford University
Age-Related Translational and Ribosomal Dysfunction and its Contribution to Neurodegeneration
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable (Joint)
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Critical Cellular Pathways in Neurodegeneration
5:00–7:00 PM
Erika L. F. Holzbaur, University of Pennsylvania
Organelle Quality Control in Neuronal Homeostasis and Neurodegeneration.
Juan S. Bonifacino, National Institutes of Health
Role of Lysosomes in the Axon in Health vs. Diseased Neurons
Pietro V. De Camilli, Yale University School of Medicine
Cellular Organelle and Lipid Dynamics
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, June 11, 2025

Breakfast
7:00–8:00 AM
Therapeutics based in Genetics and Cellular Pathways
8:00–11:00 AM
Timothy A. Ryan, Weill Medical College of Cornell University
Dysregulation of Central Metabolism Pathways in Parkinson’s Disease and New Therapeutic Strategies
Azad Bonni, Roche
Talk Title to be Announced
Speaker to be Announced
Sarah DeVos, Denali Therapeutics
Transporting Different Drug Modalities Across the BBB Using Transferrin Receptor
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Workshop 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Transformative New Technologies in Molecular and Cellular Neuroscience and Disease
5:00–6:45 PM
Jennifer A. Lippincott-Schwartz, HHMI Janelia Research Campus
Visualizing Organelle Trafficking and Metabolism in Healthy and Diseased Neurons
Andrew Bassett, Wellcome Sanger Institute
Massively Parallel Profiling of Neuronal and Glial Perturbation States
Michael E. Ward, NIH
Leveraging iPSC Models and ‘Omics to Study Neurodegeneration
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Thursday, June 12, 2025

Departure
12:00–11:59 PM

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