Membrane transporters facilitate the uptake of nutrients, ions, hormones, neurotransmitters, vitamins, and xenobiotics required for cell function and energetics as well as the export of toxic or excess molecules. Solute Carrier transporters make up the second-largest fraction of the membrane proteome, but have been under-utilized as drug targets. Although there are a few success stories of drugs targeting SLCs, we need to better determine their transport function, mechanism, regulation and physiological connection to biological processes to properly evaluate their therapeutic potential in drug discovery. In parallel, we need better tool compounds, computational modelling and high-throughput technologies to improve on their pharmacological control and diagnostic value. This conference brings together researchers focused on SLC transporter pharmacology, physiology and structure-function-mechanism in an effort to facilitate and promote a coordinated effort and understanding of these important proteins, with a strong emphasis on transporters as emerging drug targets. As outcome of the meeting we expect the creation of a cohesive research community on the medical and pharmacological exploitation of human membrane transporters as emerging drug targets and gates to drug access. New solutions and recommendations for the interpretation of genomic variants. Identification of new paths to transporter drug discovery.