Joint with: Neural Influence on Cancer, Tumor Microenvironment and Cancer Immunology
Tumor Microenvironment: Metastasis and the Host
Jan 18–21, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Mikala Egeblad, Julio Aguirre-Ghiso and Manuel Valiente
In Person
On Demand
Jan 18–21, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Mikala Egeblad, Julio Aguirre-Ghiso and Manuel Valiente
Available Formats:
In Person
On Demand
Supported by Chinese Society for Cell Biology, (Cell Research)
Available Formats: = In Person = On Demand
Saturday, January 18, 2025
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Riverview Lounge
Welcome Mixer
6:00–8:00 PM
Riverview Lounge
Sunday, January 19, 2025
Breakfast
7:00–8:00 AM
Alberta/New Brunswick
Welcome and Keynote Address
8:00–9:00 AM
Cascade Ballroom
Eduard Batlle, Institute for Research in Biomedicine
Plasticity, therapy resistance and immune evasion in metastatic colorectal cancer
Plasticity, therapy resistance and immune evasion in metastatic colorectal cancer
The Disseminated Cell in the Metastatic Niche
9:00–11:15 AM
Cascade Ballroom
Julio Aguirre-Ghiso, Montefiore Einstein Cancer Center
Plasticity of Cancer Cells and Dormancy Programs
Plasticity of Cancer Cells and Dormancy Programs
Leah Cook, NCI, National Institutes of Health
Anti-Metastatic Bone Niches in Prostate Cancer
Anti-Metastatic Bone Niches in Prostate Cancer
Eric S. Lightcap, HiberCell
Talk Title to be Announced
Talk Title to be Announced
Elena Guido Vinzoni, ETH
Short Talk: In Vivo Crispra Screen of Ligands and Receptors in Liver Endothelial Cells Highlights the Impact of Early Interactions During Colorectal Cancer Metastatic Seeding
Short Talk: In Vivo Crispra Screen of Ligands and Receptors in Liver Endothelial Cells Highlights the Impact of Early Interactions During Colorectal Cancer Metastatic Seeding
Coffee Break
9:30–9:50 AM
Riverview Lounge
Poster Setup
11:15–1:00 PM
Alberta/New Brunswick
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Alberta/New Brunswick
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Cascade Ballroom
Alexandra Mousset, Institute of Research on Cancer and Aging, Nice (IRCAN)
Neutrophil Extracellular Traps Formed During Chemotherapy Confer Treatment Resistance Via TGF-Β Activation
Neutrophil Extracellular Traps Formed During Chemotherapy Confer Treatment Resistance Via TGF-Β Activation
Jelani C. Zarif, Johns Hopkins University School of Medicine
Don Nguyen, Yale School of Medicine
Epigenetic Regulation of Tumor Cell Clustering and Metastasis in Lung Adenocarcinoma
Epigenetic Regulation of Tumor Cell Clustering and Metastasis in Lung Adenocarcinoma
Christoph A Reichel, Department of Otorhinolaryngology, LMU Munich/Germany
Granulopoiesis and Thrombopoiesis Aberrantly Synergize in Cancer to Promote Tumor Progression
Granulopoiesis and Thrombopoiesis Aberrantly Synergize in Cancer to Promote Tumor Progression
Yuto Hamazaki, The University of Tokyo
Deciphering the Diversity of Cells and Exosome in Metastatic Mechanisms
Deciphering the Diversity of Cells and Exosome in Metastatic Mechanisms
Matthew Eason, University of Maryland School of Medicine
Pleckstrin Homology Domains Regulate PI3K/Akt to Quiet the Invasive Matrix Metalloproteinase Milieu and Block Breast Cancer Dissemination
Pleckstrin Homology Domains Regulate PI3K/Akt to Quiet the Invasive Matrix Metalloproteinase Milieu and Block Breast Cancer Dissemination
Coffee Available
4:30–5:00 PM
Riverview Lounge
Microenvironmental Regulation of Metastasis
5:00–7:00 PM
Cascade Ballroom
Daniela F. Quail, McGill University
Obesity as a Driver of Pro-Metastatic Niche Formation
Obesity as a Driver of Pro-Metastatic Niche Formation
Anwesha Dey, Genentech, Inc.
Targeting the Hippo Pathway in Cancer, Fibrosis, wound Healing and Regenerative Medicine
Targeting the Hippo Pathway in Cancer, Fibrosis, wound Healing and Regenerative Medicine
Clare M Isacke, Institute of Cancer Research
Microenvironmental Changes Driving Breast Cancer Metastatic Relapse
Microenvironmental Changes Driving Breast Cancer Metastatic Relapse
Laura Alvaro, CNIO
Short Talk: Targeting a Disease-Associated Subpopulation of Macrophages/ Microglia Uncovers a Novel Vulnerability of Brain Metastasis
Short Talk: Targeting a Disease-Associated Subpopulation of Macrophages/ Microglia Uncovers a Novel Vulnerability of Brain Metastasis
Meera Murgai, National Cancer Institute, National Institutes of Health
Short Talk: Pericyte-Tumor Crosstalk Promotes Metastatic Tumor Dormancy Through Calcium Activated Phospholipid Transfer.
Short Talk: Pericyte-Tumor Crosstalk Promotes Metastatic Tumor Dormancy Through Calcium Activated Phospholipid Transfer.
Social Hour with Lite Bites
7:00–8:00 PM
Alberta/New Brunswick
Posters
7:30–10:00 PM
Alberta/New Brunswick
Monday, January 20, 2025
Breakfast
7:00–8:00 AM
Alberta/New Brunswick
Defining and Shaping the Metastatic Microenvironment (Joint)
8:00–11:00 AM
Cascade Ballroom
Michael Angelo, Stanford University
Spatially Encoded Risk Predictors of Cancer Outcomes
Spatially Encoded Risk Predictors of Cancer Outcomes
Devon A. Lawson, University of California, Irvine
Immune Control of Breast Cancer Brain Metastasis
Immune Control of Breast Cancer Brain Metastasis
David Lyden, Weill Cornell Medical College
Tumor Induced Liver Metabolic Dysfunction Drives Metastasis
Tumor Induced Liver Metabolic Dysfunction Drives Metastasis
Mikala Egeblad, Cold Spring Harbor Laboratory
Immune Control and Escape at the Metastatic Site
Immune Control and Escape at the Metastatic Site
Alexandra Newman, New York University
Short Talk: Myocardial Infarction Increases Metastatic Cancer in The Lung
Short Talk: Myocardial Infarction Increases Metastatic Cancer in The Lung
Morgan Fox, University of Colorado
Short Talk: Non-Canonical Activation of FGFR1 Drives ER+ Breast Cancer Brain Metastasis in the Aged and E2-Depleted TME
Short Talk: Non-Canonical Activation of FGFR1 Drives ER+ Breast Cancer Brain Metastasis in the Aged and E2-Depleted TME
Coffee Break
9:00–9:20 AM
Riverview Lounge
Poster Setup
11:00–1:00 PM
Alberta/New Brunswick
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Alberta/New Brunswick
Career Roundtable (Joint)
3:00–4:30 PM
Alhambra
Coffee Available
4:30–5:00 PM
Riverview Lounge
The Brain-Body Axis in Metastasis (Joint)
5:00–7:00 PM
Cascade Ballroom
Humsa Venkatesh, Brigham and Women's Hospital
Neuronal-Activity Dependent Mechanisms of Small Cell Lung Cancer Progression
Neuronal-Activity Dependent Mechanisms of Small Cell Lung Cancer Progression
Manuel Valiente, Spanish National Cancer Research Centre
Strategies to Challenge Brain Metastasis Lethality in Mice and Human/The Effects of Brain Metastasis on Neural Circuits
Strategies to Challenge Brain Metastasis Lethality in Mice and Human/The Effects of Brain Metastasis on Neural Circuits
Erica K Sloan, Monash University
Blocking Stress Signaling to Control Metastatic Breast Cancer
Blocking Stress Signaling to Control Metastatic Breast Cancer
Golnaz Morad, MD Anderson Cancer Center
Short Talk: Metastatic Brain Tumors Harbor Intracellular Bacterial Signals Associated with the Oral Microbiota
Short Talk: Metastatic Brain Tumors Harbor Intracellular Bacterial Signals Associated with the Oral Microbiota
Kylynda C Bauer, National Institutes of Health - National Cancer Institute
Short Talk: Gut Microbiome Modulates Liver Cancer Via Neuroimmune Crosstalk
Short Talk: Gut Microbiome Modulates Liver Cancer Via Neuroimmune Crosstalk
Social Hour with Lite Bites
7:00–8:00 PM
Alberta/New Brunswick
Posters
7:30–10:00 PM
Alberta/New Brunswick
Tuesday, January 21, 2025
Breakfast
7:00–8:00 AM
Alberta/New Brunswick
Cancer Cell Plasticity and Evolution During Metastasis
8:00–11:00 AM
Cascade Ballroom
Samra Turajlic, Francis Crick Institute
Talk Title to be Announced
Talk Title to be Announced
Jean-Christophe W Marine, Vlaams Interuniversitair Instituut, Katholieke Universiteit Leuven
Influence of the Niche on Cancer Cell Hierarchy
Influence of the Niche on Cancer Cell Hierarchy
Gelareh Zadeh, University Health Network
Talk Title to Be Announced
Talk Title to Be Announced
Ashley M Laughney, Weill Cornell Medicine
Tackling the Genotype-to-Phenotype Problem in Cancer Evolution
Tackling the Genotype-to-Phenotype Problem in Cancer Evolution
Myriam Labelle, St. Jude Children's Research Hospital
Short Talk: ZBTB18 Limits Tumor Cell Pliancy and Tumor Cell-Immune Cell Crosstalk to Inhibit Metastasis
Short Talk: ZBTB18 Limits Tumor Cell Pliancy and Tumor Cell-Immune Cell Crosstalk to Inhibit Metastasis
Maria S Sosa, Albert Einstein College of Medicine
Coffee Break
9:00–9:20 AM
Riverview Lounge
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Cascade Ballroom
Yunfan Sun, Zhongshan Hospital, Fudan University
Spatiotemporal Multi-Omics Uncover Tumor Ecosystem Dynamics Driving Metastatic Colonization
Spatiotemporal Multi-Omics Uncover Tumor Ecosystem Dynamics Driving Metastatic Colonization
Rebecca Dodd, University of Iowa
Epigenetic Plasticity Drives Sarcoma Metastasis through PRC2-Dependent Stromal Remodeling and IL-17D Signaling
Epigenetic Plasticity Drives Sarcoma Metastasis through PRC2-Dependent Stromal Remodeling and IL-17D Signaling
Anna Adam Artigues, Albert Einstein College of Medicine
Peripheral Sympathetic Nerve Damage Induces a Loss of Brain Niche Homeostasis Stimulating Metastatic Outgrowth of Disseminated Cancer Cells.
Peripheral Sympathetic Nerve Damage Induces a Loss of Brain Niche Homeostasis Stimulating Metastatic Outgrowth of Disseminated Cancer Cells.
Jonathan Rennhack, Loyola University Chicago
Transcription Factor Dynamics Induced by Cytokine Interaction in Metastatic Sites of Colorectal Cancer
Transcription Factor Dynamics Induced by Cytokine Interaction in Metastatic Sites of Colorectal Cancer
Mary Clare Beytagh, UCSF
Dissecting Mechanisms of Medulloblastoma Metastasis in Vivo
Dissecting Mechanisms of Medulloblastoma Metastasis in Vivo
Sergei Grivennikov, Cedars-Sinai Medical Center
Microbiota Induced Cytokines Control Anti-Tumor Immunity and Colorectal Cancer Metastasis.
Microbiota Induced Cytokines Control Anti-Tumor Immunity and Colorectal Cancer Metastasis.
Coffee Available
4:30–5:00 PM
Riverview Lounge
Engineering and Targeting of Host Mechanisms of Metastasis
5:00–6:45 PM
Cascade Ballroom
Ronit Satchi-Fainaro, Tel Aviv University
3D Bioprinted Cancer Models: From Basic Biology to Drug Development
3D Bioprinted Cancer Models: From Basic Biology to Drug Development
Daniel A. Heller, Memorial Sloan Kettering Cancer Center
Nanotherapeutic Targeting of Metastatic Cancer to the Brain
Nanotherapeutic Targeting of Metastatic Cancer to the Brain
Edgar G. Engleman, Stanford University School of Medicine
Harnessing Innate Immune Response to Reduce Metastatic Seeding
Harnessing Innate Immune Response to Reduce Metastatic Seeding
Pierina Barturen-Larrea, California Institute of Technology
Short Talk: Acoustic Reporter Genes for In Situ Monitoring of Metastasis Dynamics
Short Talk: Acoustic Reporter Genes for In Situ Monitoring of Metastasis Dynamics
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Cascade Ballroom
Social Hour with Lite Bites
7:00–8:00 PM
Alberta/New Brunswick
Trivia
8:00–9:00 PM
Cascade Ballroom
Wednesday, January 22, 2025
Departure
12:00–11:59 PM
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