Vaccinology: Horizons Across Disease, Demography and Technology
Jun 04–07, 2025 | Marriott Marquis Washington, DC, Washington, DC, United States
Scientific Organizers:
Rino Rappuoli, Kanta Subbarao, Laurence Zitvogel and Firdausi Qadri
Livestream
In Person
On Demand
Jun 04–07, 2025 | Marriott Marquis Washington, DC, Washington, DC, United States
Scientific Organizers:
Rino Rappuoli, Kanta Subbarao, Laurence Zitvogel and Firdausi Qadri
Available Formats:
Supported by:
Livestream
In Person
On Demand
Available Formats: = Livestream = In Person = On Demand
Fundraising
Merchandise Options
Registration Options
Wednesday, June 4, 2025
Booking Function
Registration
11:00–4:30 PM
Thursday, June 5, 2025
Breakfast
7:30–8:30 AM
Independence Salons FGH
Poster Setup
8:00–8:30 AM
Independence Salon E
Poster Viewing
8:00–5:00 PM
Independence Salon E
Welcome and Keynote Address
8:30–9:30 AM
Independence Salon E
Peter J. Hotez, Baylor College of Medicine
Vaccines and Immunizations in a Time of Global Boiling, Megacities, and Antiscience
Vaccines and Immunizations in a Time of Global Boiling, Megacities, and Antiscience
Infectious Insights Podcast Introduction
9:30–9:40 AM
Independence Salon E
Learning the Molecular Immunology of mRNA Vaccines
9:40–11:45 AM
Independence Salon E
Bali Pulendran, Stanford University School of Medicine
Comparative Responses to mRNA and Adjuvanted Vaccines
Comparative Responses to mRNA and Adjuvanted Vaccines
Ali H. Ellebedy, Washington University School of Medicine
B Cell Responses to mRNA Vaccination/Induction of New Epitopes
B Cell Responses to mRNA Vaccination/Induction of New Epitopes
Rita Carsetti, Bambino Gesù Children Hospital
Early Immune Responses to Vaccination
Early Immune Responses to Vaccination
Michela Locci, University of Pennsylvania
Short Talk: Distinct Components of Nucleoside-modified Messenger RNA Vaccines Cooperate to Instruct Efficient T Follicular Helper Cell Responses
Short Talk: Distinct Components of Nucleoside-modified Messenger RNA Vaccines Cooperate to Instruct Efficient T Follicular Helper Cell Responses
Coffee Break
10:10–10:30 AM
Foyer
Lunch
11:45–12:45 PM
Independence Salons FGH
Poster Session 1
12:00–2:30 PM
Independence Salon E
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Independence Salon E
Namit Chaudhary, Scripps Research
Alumina-coated Microparticles Enable Extended Antigen Delivery of HIV Immunogens in a Single Shot
Alumina-coated Microparticles Enable Extended Antigen Delivery of HIV Immunogens in a Single Shot
Grace Freeman, National Institutes of Health
Isolation of Monoclonal Antibodies against H5Nx Influenza Viruses from Individuals Immunized with a Monovalent H5N1 Vaccine
Isolation of Monoclonal Antibodies against H5Nx Influenza Viruses from Individuals Immunized with a Monovalent H5N1 Vaccine
Grace Hendricks, University of Washington
Computationally Designed mRNA-launched Protein Nanoparticle Immunogens as an Integrated Vaccine Platform
Computationally Designed mRNA-launched Protein Nanoparticle Immunogens as an Integrated Vaccine Platform
Fnu Alakesh, Stanford University
Understanding the Immune Landscape behind TLR-based Hydrogel Vaccines
Understanding the Immune Landscape behind TLR-based Hydrogel Vaccines
Artem Ashurov, University Hospital of Cologne
Structural Characterization of Antibodies for Synergistic HCMV Neutralization
Structural Characterization of Antibodies for Synergistic HCMV Neutralization
Sacha Zinn, Garvan Institute of Medical Research
Tailoring SARS-CoV-2 humoral Responses using mRNA Expressed mAbs
Tailoring SARS-CoV-2 humoral Responses using mRNA Expressed mAbs
Giovanna de Brito Carneiro, Instituto Butantan
A Fusion of the Adenylate Cyclase Toxoid from Bordetella Pertussis and Fragments of Pneumococcal Surface Protein A Confers High Protection to Mice against Diseases caused by Streptococcus Pneumoniae
A Fusion of the Adenylate Cyclase Toxoid from Bordetella Pertussis and Fragments of Pneumococcal Surface Protein A Confers High Protection to Mice against Diseases caused by Streptococcus Pneumoniae
Hervé Besançon, University of California, San Diego
A STING-Adjuvanted Outer Membrane Vesicle Nanoparticle Vaccine Against Klebsiella pneumoniae
A STING-Adjuvanted Outer Membrane Vesicle Nanoparticle Vaccine Against Klebsiella pneumoniae
Coffee Available
4:30–5:00 PM
Foyer
Vaccines, Emerging Reality in Cancer Therapy
5:00–7:00 PM
Independence Salon E
Catherine J Wu, Dana-Farber Cancer Institute
DNA-Based Cancer Vaccines
DNA-Based Cancer Vaccines
Ira Mellman, Medici Therapeutics
Combining Checkpoints Inhibitor Immunotherapy and Personalized Vaccines
Combining Checkpoints Inhibitor Immunotherapy and Personalized Vaccines
Laura K. Mackay, University of Melbourne
Defining TRM cell Fate: The Combined Influence of TCR Signaling and Tissue Instruction
Defining TRM cell Fate: The Combined Influence of TCR Signaling and Tissue Instruction
Shuang Chen, UT Southwestern Medical Center
Short Talk: Systemic STING Nanovaccine for HPV-Induced Cancer Therapy
Short Talk: Systemic STING Nanovaccine for HPV-Induced Cancer Therapy
Xinbo Gao, Tianjin Medical University
Short Talk: Enhancing Pancreatic Cancer Vaccines with OX40 Agonist and PD-1 Inhibitor to Synergize Antitumor Immunity and Reshape the Immune Microenvironment
Short Talk: Enhancing Pancreatic Cancer Vaccines with OX40 Agonist and PD-1 Inhibitor to Synergize Antitumor Immunity and Reshape the Immune Microenvironment
On Own for Dinner
7:00–8:00 PM
Friday, June 6, 2025
Breakfast
7:30–8:30 AM
Independence Salons FGH
Preparing for New Pandemics and Emerging Infections
8:30–11:30 AM
Independence Salon E
Penny L Moore, University of the Witwatersrand and National Institute for Communicable Diseases
Views from the African Continent
Views from the African Continent
Kanta Subbarao, Université Laval
WHO Strategy, One Health Considerations, Equity
WHO Strategy, One Health Considerations, Equity
Cristina Cassetti, Independent Expert, Retired Division Deputy Director at NIAID
Prototype Vaccines
Prototype Vaccines
Rino Rappuoli, Fondazione Biotecnopolo di Siena
An Institute for Pandemic Preparedness
An Institute for Pandemic Preparedness
Masaru Kanekiyo, NIAID, National Institutes of Health
Short Talk: A Mosaic Nanoparticle Displaying Stabilized Stem Trimers of Multiple Hemagglutinin Subtypes Elicits Broadly Cross-Reactive and Protective Immunity in Nonhuman Primates
Short Talk: A Mosaic Nanoparticle Displaying Stabilized Stem Trimers of Multiple Hemagglutinin Subtypes Elicits Broadly Cross-Reactive and Protective Immunity in Nonhuman Primates
Nitesh Mishra, The Scripps Research Institute
Short Talk: Machine Learning Enabled Conformational Mapping Optimizes Lassa Virus Vaccine Candidates
Short Talk: Machine Learning Enabled Conformational Mapping Optimizes Lassa Virus Vaccine Candidates
Coffee Break
9:30–9:50 AM
Foyer
Award Recipient Acknowledgement
9:50–9:55 AM
Independence Salon E
Poster Setup
11:30–1:00 PM
Independence Salon E
On Own for Lunch
11:30–2:45 PM
Career Roundtable
1:00–2:30 PM
Independence Salon E
Poster Viewing
1:00–10:00 PM
Independence Salon E
Panel Discussion: Transforming Early-Stage Vaccine Development
3:45–4:30 PM
Independence Salon E
* Rino Rappuoli, Fondazione Biotecnopolo di Siena
Panel Moderator
Panel Moderator
John Tsang, Yale University School of Medicine
Panelist
Panelist
Neil P King, University of Washington
Panelist
Panelist
Firdausi Qadri, International Centre for Diarrhoeal Disease Research
Panelist
Panelist
Coffee Available
4:30–5:00 PM
Foyer
Understanding Mechanistic Immunology to Drive Vaccine Design
5:00–7:00 PM
Independence Salon E
Michel C. Nussenzweig, HHMI/Rockefeller University
Germinal Center Selection
Germinal Center Selection
Emanuele Andreano, Fondazione Toscana Life Sciences
B Cell Responses
B Cell Responses
Matthew J Wiest, University of Michigan
Short Talk: Heterologous Prime-pull Immunization Strategies for SARS-CoV-2 Drives Enhanced, Long-lived Mucosal and Systemic Cellular and Antibody Responses
Short Talk: Heterologous Prime-pull Immunization Strategies for SARS-CoV-2 Drives Enhanced, Long-lived Mucosal and Systemic Cellular and Antibody Responses
Vishal N Rao, Icahn School of Medicine at Mount Sinai
Short Talk: Convergent and Clonotype-enriched Mutations Drive Affinity Maturation of a Public Antibody
Short Talk: Convergent and Clonotype-enriched Mutations Drive Affinity Maturation of a Public Antibody
Social Hour with Lite Bites
7:00–8:00 PM
Independence Salons FGH
Poster Session 2
7:30–10:00 PM
Independence Salon E
Saturday, June 7, 2025
Breakfast
7:30–8:30 AM
Independence Salons FGH
Designing and Evaluating New Vaccines
8:30–11:30 AM
Independence Salon E
Jason S McLellan, The University of Texas at Austin
Structure Based Design
Structure Based Design
Wolfgang W Leitner, National Institute of Allergy and Infectious Diseases, NIH, DHHS
NIH Adjuvant Program
NIH Adjuvant Program
Galit Alter, Ragon Institute of MGH, MIT, and Harvard
Mechanistic and Non Mechanistic Correlates of Protection
Mechanistic and Non Mechanistic Correlates of Protection
Florian Krammer, Icahn School of Medicine at Mount Sinai
Development of Broadly Protective Vaccines to Antigenically Variable Viruses
Development of Broadly Protective Vaccines to Antigenically Variable Viruses
Alessandro Sette, La Jolla Institute for Immunology
Short Talk: The Identification and Validation of Conserved T Cell Epitope Regions in Viral Pathogen Families with Pandemic Potential
Short Talk: The Identification and Validation of Conserved T Cell Epitope Regions in Viral Pathogen Families with Pandemic Potential
Mihai L Azoitei, Duke University
Short Talk: Development and Validation of Pan-Betacoronavirus Vaccine Candidates that Target the S2 Domain of Spike
Short Talk: Development and Validation of Pan-Betacoronavirus Vaccine Candidates that Target the S2 Domain of Spike
Coffee Break
9:30–9:50 AM
Foyer
Innovations in Vaccine Science: Advancing Precision Medicine
11:30–12:45 PM
Independence Salon E
Courtney L Page, Wake Forest University School of Medicine
An Influenza HA-expressing mRNA-LNP vaccine induces potent and protective responses in newborn NHP
An Influenza HA-expressing mRNA-LNP vaccine induces potent and protective responses in newborn NHP
Florian W Gegenfurtner, Karolinska Institutet
Antibody Responses to Pneumoviruses Fluctuate During Life – Implications for RSV Vaccination
Antibody Responses to Pneumoviruses Fluctuate During Life – Implications for RSV Vaccination
Murilo Sena Amaral, Instituto Butantan
Protection in Rhesus Macaques Against Schistosoma Mansoni Induced by a Multi-Epitope Vaccine Candidate
Protection in Rhesus Macaques Against Schistosoma Mansoni Induced by a Multi-Epitope Vaccine Candidate
Elizabeth M Villasis, Universidad Peruana Cayetano Heredia
Assessment of the Functional Role of Purified Antibodies from Asymptomatic P. vivax-infected Individuals from the Peruvian Amazon using P. Knowlesi in vitro Culture Model
Assessment of the Functional Role of Purified Antibodies from Asymptomatic P. vivax-infected Individuals from the Peruvian Amazon using P. Knowlesi in vitro Culture Model
Kobporn Boonnak, Siriraj Hospital, Mahidol University
Characterization of Neutralizing Versus Binding Antibody and T Cell Responses to Varicellar-zoster Virus in the Elderly
Characterization of Neutralizing Versus Binding Antibody and T Cell Responses to Varicellar-zoster Virus in the Elderly
On Own for Lunch
12:45–2:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Independence Salon E
Marie Pancera, Fred Hutchinson Cancer Center
Structural Basis for Antibody Cross-neutralization of Dengue and Zika Viruses
Structural Basis for Antibody Cross-neutralization of Dengue and Zika Viruses
Natacha Madelon, University of Geneva
Reactogenicity to mRNA Vaccines is Linked to Heightened Inflammatory Responses Driven by Vaccine-specific Antibody Responses and Host-intrinsic Factors
Reactogenicity to mRNA Vaccines is Linked to Heightened Inflammatory Responses Driven by Vaccine-specific Antibody Responses and Host-intrinsic Factors
Maya Sangesland, National Institutes of Health
Functional, Immunogenetic, and Structural Convergence in Influenza Immunity between Humans and Macaques
Functional, Immunogenetic, and Structural Convergence in Influenza Immunity between Humans and Macaques
Bo Zhang, Fred Hutchinson Cancer Center
CD4+ T Cell Responses to Vaccination in People with HIV Correlate with Risk of COVID-19 in the CoVPN 3008 Clinical Trial
CD4+ T Cell Responses to Vaccination in People with HIV Correlate with Risk of COVID-19 in the CoVPN 3008 Clinical Trial
Nicholas Cheang, National University of Singapore
Intranasal Dendritic Cell-targeting Vaccine Booster Elicits Cross-clade, Durable and Protective Systemic and Mucosal Immunity against Sarbecoviruses.
Intranasal Dendritic Cell-targeting Vaccine Booster Elicits Cross-clade, Durable and Protective Systemic and Mucosal Immunity against Sarbecoviruses.
Sylvain Baize, Institut Pasteur
Immunogenicity and Efficacy of Vaccines against Crimean-Congo Hemorrhagic Fever Virus Based on Mopevac, a New Live-Attenuated Virus Vaccine Platform
Immunogenicity and Efficacy of Vaccines against Crimean-Congo Hemorrhagic Fever Virus Based on Mopevac, a New Live-Attenuated Virus Vaccine Platform
Coffee Available
4:30–5:00 PM
Foyer
Exploiting Tissue Specific Protection to Prevention and Cure
5:00–6:45 PM
Independence Salon E
Yasmine Belkaid, Institut Pasteur
Immune Control of Maternal Physiology
Immune Control of Maternal Physiology
Laurence Zitvogel, Institut Gustave Roussy
Gut Microbiota Impacts the Immunogenicity of Vaccines
Gut Microbiota Impacts the Immunogenicity of Vaccines
Christopher Chiu, Imperial College London
Clinical Trials for Intranasal and Aerosol SARS-CoV-2 Vaccine Development
Clinical Trials for Intranasal and Aerosol SARS-CoV-2 Vaccine Development
Kerrie Sandgren, Westmead Institute for Medical Research
Short Talk: Adjuvant As01 Activates an Innate Immune Cascade in Human Lymph Node Explants, Initiated by Subcapsular Sinus-Lining Macrophages, in an Age-Independent Manner
Short Talk: Adjuvant As01 Activates an Innate Immune Cascade in Human Lymph Node Explants, Initiated by Subcapsular Sinus-Lining Macrophages, in an Age-Independent Manner
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Independence Salon E
Social Hour with Lite Bites
7:00–8:00 PM
Independence Salons FGH
Trivia!
8:00–9:00 PM
Independence Salon E
Sunday, June 8, 2025
Departure
12:00–11:59 PM
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