Myeloid Targeting Strategies for Cancer Treatment
May 6-9, 2024 | INEC Killarney Convention Centre, Killarney, KY, Ireland
Scientific Organizers:
Miriam Merad and Matthew F. Krummel
In Person
On Demand
May 6-9, 2024 | INEC Killarney Convention Centre, Killarney, KY, Ireland
Scientific Organizers:
Miriam Merad and Matthew F. Krummel
Available Formats:
In Person
On Demand
Supported by the Directors' Fund
Available Formats: = In Person = On Demand
Merchandise Options
Registration Options
Booking Function
Fundraising
Monday, May 6, 2024
Arrival and Registration
4:00–8:00 PM
INEC Foyer
Welcome Mixer
6:00–8:00 PM
INEC Foyer
Tuesday, May 7, 2024
Breakfast
7:00–8:00 AM
Individual Hotel
Welcome and Keynote Address
8:00–9:00 AM
INEC Main Auditorium
* Miriam Merad, Mount Sinai School of Medicine
Session Chair
Session Chair
* Matthew F. Krummel, University of California, San Francisco
Session Chair
Session Chair
Martin Guilliams, Ghent University - VIB
DC and Macrophage Diversity in Health and Diseases
DC and Macrophage Diversity in Health and Diseases
Developmental Regulation of Myeloid Cells in Cancer and Beyond
9:00–11:15 AM
INEC Main Auditorium
Miriam Merad, Mount Sinai School of Medicine
Enhancing DC Function in the TME
Enhancing DC Function in the TME
* Christine Carine Moussion, Genentech, Inc.
Spatial Organization of Myeloid Programs in the TME
Spatial Organization of Myeloid Programs in the TME
Merav Cohen, Tel-Aviv University
Myeloid Cellular Cross-Talks During Cancer Development
Myeloid Cellular Cross-Talks During Cancer Development
Robert Samstein, Icahn School of Medicine at Mount Sinai
Short Talk: HLA Class II Mediated Immune Surveillance of Lung Cancer
Short Talk: HLA Class II Mediated Immune Surveillance of Lung Cancer
Coffee Break
9:30–9:50 AM
INEC Foyer
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
INEC Foyer
Poster Viewing
1:00–10:00 PM
INEC Foyer
Career Roundtable
3:30–4:30 PM
INEC Main Auditorium
Judith A. Varner, University of California, San Diego
Professor, Pathology
Professor, Pathology
Venkataraman Sriram, Foundery Innovations
Founder, Managing Member, & Chief Scientific Officer
Founder, Managing Member, & Chief Scientific Officer
Matteo Iannacone, San Raffaele Scientific Institute & University
Group Leader
Group Leader
Coffee Available
4:30–5:00 PM
INEC Foyer
Enhancing DC Functionality in the TME
5:00–7:00 PM
INEC Main Auditorium
* Matthew F. Krummel, University of California, San Francisco
Session Chair
Session Chair
* Miriam Merad, Mount Sinai School of Medicine
Session Chair
Session Chair
Rony Dahan, Weizmann Institute of Science
Antibody Targeting of Dendritic Cells in Cancer
Antibody Targeting of Dendritic Cells in Cancer
Ruth Lan, Asher Biotherapeutics
Cell-Specific Cytokine Delivery
Cell-Specific Cytokine Delivery
Livia Lacerda Mariano, Institute Curie
Short Talk: The TRPML1 Calcium Lysosomal Channel Controls Dendritic Cell Migration and Anti-tumor Immunity
Short Talk: The TRPML1 Calcium Lysosomal Channel Controls Dendritic Cell Migration and Anti-tumor Immunity
Raphael Mattiuz, Icahn School of Medicine at Mount Sinai
Short Talk: Dendritic Cells Form and Maintain Tertiary Lymphoid Structures (TLSs) in Cancer Contributing to Immunotherapeutic Responses
Short Talk: Dendritic Cells Form and Maintain Tertiary Lymphoid Structures (TLSs) in Cancer Contributing to Immunotherapeutic Responses
Social Hour with Lite Bites
7:00–8:00 PM
INEC Foyer
Poster Session 1
7:30–10:00 PM
INEC Foyer
Wednesday, May 8, 2024
Breakfast
7:00–8:00 AM
Individual Hotel
Boosting Macrophage Tumorigenic Function
8:00–11:00 AM
INEC Main Auditorium
* Julie Helft, Institut Cochin
FOLR2+ Macs and Antitumor Immunity
FOLR2+ Macs and Antitumor Immunity
Jennifer Guerriero, Brigham and Women's Hospital
Metabolic Targeting of Tumor Macrophages
Metabolic Targeting of Tumor Macrophages
* Philippe Benaroch, INSERM Institut Curie
Myeloid Cell Engineering for Anti-Tumor Treatments
Myeloid Cell Engineering for Anti-Tumor Treatments
Ido Amit, Weizmann Institute
Mapping Macrophages Inflammatory Programs
Mapping Macrophages Inflammatory Programs
Florent Ginhoux, Singapore Immunology Network
Regulation of Monocyte-Derived Cells Differentiation in Inflamed Tissues
Regulation of Monocyte-Derived Cells Differentiation in Inflamed Tissues
Meijun Wang, City University of Hong Kong (Shenzhen) Research Institute
Short Talk: Investigate the Role of IRF5 in Macrophages and Myeloid Cells in Anti-Tumor Immunity
Short Talk: Investigate the Role of IRF5 in Macrophages and Myeloid Cells in Anti-Tumor Immunity
Lea Feldmann, Institut Pasteur
Short Talk: Understanding the Antitumoral Activity of CAR-Macrophages
Short Talk: Understanding the Antitumoral Activity of CAR-Macrophages
Coffee Break
9:00–9:20 AM
INEC Foyer
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
INEC Foyer
Poster Viewing
1:00–10:00 PM
INEC Foyer
Workshop
2:30–4:30 PM
INEC Main Auditorium
Dalton Hermans, National Institutes of Health
ACT-VAX-INNATE: An Integrated Approach for Enhancing Tumor Control with Adoptive T Cell Therapy
ACT-VAX-INNATE: An Integrated Approach for Enhancing Tumor Control with Adoptive T Cell Therapy
* Alexander B. Sigalov, SignaBlok, Inc.
Ligand-Independent TREM-1 Blockade in Cancer Treatment
Ligand-Independent TREM-1 Blockade in Cancer Treatment
Thomas Jaquin, IOmx Therapeutics AG
IOMX-0675 , a LILRB1 and LILRB2 Cross-Specific Antibody, Effectively Repolarizes Immunosuppressive Myeloid Cells and Activates T Cells Leading to Potent Tumor Cell Killing
IOMX-0675 , a LILRB1 and LILRB2 Cross-Specific Antibody, Effectively Repolarizes Immunosuppressive Myeloid Cells and Activates T Cells Leading to Potent Tumor Cell Killing
Martina Molgora, Washington University School of Medicine
Lack of TREM2 During anti-PD1 Therapy Reprograms Intestinal Macrophages and Microbiota to Enhance Tumor Rejection
Lack of TREM2 During anti-PD1 Therapy Reprograms Intestinal Macrophages and Microbiota to Enhance Tumor Rejection
Daniela C Cerezo-Wallis, Yale University
Cancer Enables Auxiliary Pathways of Granulopoiesis to Potentiate Tumorassociated Neutrophils
Cancer Enables Auxiliary Pathways of Granulopoiesis to Potentiate Tumorassociated Neutrophils
* Damya Laoui, Vrije Universiteit Brussel-VIB
Intratumoral Delivery of Lipid Nanoparticle-Formulated mRNA Encoding IL-21, IL-7, and 4-1BBL Induces Anti-Tumor Immunity
Intratumoral Delivery of Lipid Nanoparticle-Formulated mRNA Encoding IL-21, IL-7, and 4-1BBL Induces Anti-Tumor Immunity
Cristina Contreras Burrola, National Cancer Institute
Going the Distance: Uncovering a Global Myeloid Reprogramming in Human Metastatic and Adjacent Microenvironments
Going the Distance: Uncovering a Global Myeloid Reprogramming in Human Metastatic and Adjacent Microenvironments
Garett Dunsmore, University of Paris Saclay
Timing and Location Dictate Monocyte Fate and Their Transition to Tumor-Associated Macrophages
Timing and Location Dictate Monocyte Fate and Their Transition to Tumor-Associated Macrophages
Coffee Available
4:30–5:00 PM
INEC Foyer
Dampening Myeloid Regulatory Programs
5:00–7:00 PM
INEC Main Auditorium
* Martin Guilliams, Ghent University - VIB
Session Chair
Session Chair
Venkataraman Sriram, Foundery Innovations
Targeting Trem2 in Cancer Patients
Targeting Trem2 in Cancer Patients
* Judith A. Varner, University of California, San Diego
Targeting Immunosupressive Macrophages
Targeting Immunosupressive Macrophages
Megan Clark, UPenn
Short Talk: Mitochondrial NDUFA4 is a Functional Switch Controlling TAM Function and Tumor Immunity
Short Talk: Mitochondrial NDUFA4 is a Functional Switch Controlling TAM Function and Tumor Immunity
Nicoletta Caronni, Ospedale San Raffaele
Short Talk: IL-1β+ Macrophages Fuel Pathogenic Inflammation in Pancreatic Cancer
Short Talk: IL-1β+ Macrophages Fuel Pathogenic Inflammation in Pancreatic Cancer
Matthew Arvedson, UCSF
Short Talk: Aire-Expressing Tumor-Associated Macrophages Promote Cancer Immune Evasion
Short Talk: Aire-Expressing Tumor-Associated Macrophages Promote Cancer Immune Evasion
Samarth Hegde, Icahn School of Medicine at Mount Sinai
Short Talk: Epigenetic Dysregulation of Myeloid Progenitors Fuel Immunosuppressive Macrophages in Tumor Microenvironment
Short Talk: Epigenetic Dysregulation of Myeloid Progenitors Fuel Immunosuppressive Macrophages in Tumor Microenvironment
Social Hour with Lite Bites
7:00–8:00 PM
INEC Foyer
Poster Session 2
7:30–10:00 PM
INEC Foyer
Thursday, May 9, 2024
Breakfast
7:00–8:00 AM
Individual Hotel
Myeloid Cell Control of the Tissue Ecosystem
8:00–11:00 AM
INEC Main Auditorium
* Matthew F. Krummel, University of California, San Francisco
Space-Time 'Movements' in Tissues
Space-Time 'Movements' in Tissues
* Laurence Zitvogel, Institut Gustave Roussy
Bile Acids Module the Gut Immune Rheostat Tuning Cancer Immunosurveillance
Bile Acids Module the Gut Immune Rheostat Tuning Cancer Immunosurveillance
Luke A. J. O'Neill, Trinity Biomedical Sciences Institute
A Break in Mitochondrial Endosymbiosis as a Basis for Inflammatory Diseases
A Break in Mitochondrial Endosymbiosis as a Basis for Inflammatory Diseases
Jo A. Van Ginderachter, Vrije Universiteit Brussel
Short Talk: Kupffer Cell-Derived MIF as Regulator of Liver Metastasis
Short Talk: Kupffer Cell-Derived MIF as Regulator of Liver Metastasis
Ayumi Kuratani, Osaka University
Short Talk: Identification of a Tumor-Specific Macrophage Subset and its Functional Analysis by Labeling and Depletion Using the Novel VeDTR Mouse System
Short Talk: Identification of a Tumor-Specific Macrophage Subset and its Functional Analysis by Labeling and Depletion Using the Novel VeDTR Mouse System
Coffee Break
9:00–9:20 AM
INEC Foyer
On Own for Lunch
11:00–5:00 PM
Coffee Available
4:30–5:00 PM
INEC Foyer
Myeloid Cells in Viral and Inflammatory Diseases
5:00–6:45 PM
INEC Main Auditorium
* Matteo Iannacone, San Raffaele Scientific Institute & University
Targeting Myeloid Cells in Viral Diseases
Targeting Myeloid Cells in Viral Diseases
* Carla V. Rothlin, Yale University
Myeloid and Stromal Crosstalk in Non-Resolving Inflammation
Myeloid and Stromal Crosstalk in Non-Resolving Inflammation
Duale A Ahmed, Carleton University
Short Talk: Vaccinia-Induced Early Anti-Tumour Immune Responses Are Dependent on Differential Reprogramming of Myeloid Cell Populations in Highly Versus Weakly Immunogenic Murine Cancer Models
Short Talk: Vaccinia-Induced Early Anti-Tumour Immune Responses Are Dependent on Differential Reprogramming of Myeloid Cell Populations in Highly Versus Weakly Immunogenic Murine Cancer Models
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
INEC Main Auditorium
Social Hour with Lite Bites
7:00–8:00 PM
INEC Foyer
Cash Bar
8:00–9:00 PM
INEC Foyer
Friday, May 10, 2024
Departure
7:00–11:59 PM
Subscribe for Updates