Mitochondrial Biology in Health and Disease

Jan 13–16, 2025 | NTUH International Convention Center, Taipei, TPE, Taiwan
Scientific Organizers: Lena Pernas, Anne N Murphy and Johan Auwerx

  In Person
  On Demand

Jan 13–16, 2025 | NTUH International Convention Center, Taipei, TPE, Taiwan
Scientific Organizers: Lena Pernas, Anne N Murphy and Johan Auwerx

Available Formats:   = In Person     = On Demand
Monday, January 13, 2025
Registration
4:00–8:00 PM
 2nd Floor Foyer
Welcome Mixer
6:00–8:00 PM
 2nd Floor Foyer
Tuesday, January 14, 2025
Breakfast
7:30–8:30 AM
 Individual Hotel
Poster Setup
8:00–8:30 AM
 2nd Floor Foyer
Poster Viewing
8:15–5:00 PM
 2nd Floor Foyer
Welcome and Keynote Address
8:30–9:30 AM
 Room 201
Navdeep S Chandel, Northwestern University
Mitochondria are Signaling Organelles
Mitochondrial Signaling at Different Scales
9:30–11:45 AM
 Room 201
Jodi Nunnari, Altos Labs
Mitochondria and Interorganellar Communication
Jared Rutter, University of Utah
Mitochondrial Metabolic Messengers
Sarah-Maria Fendt, VIB-KU Leuven
Metabolic Regulation of Metastasis Formation
Jingchuan Luo †, Whitehead Institute
Short Talk: Deciphering the Logic of Mammalian Mitochondrially-Localized Translation through Optogenetically-Controlled Proximity-Specific Ribosome Profiling
Coffee Break
10:00–10:20 AM
 2nd Floor Foyer
Lunch
11:45–12:45 PM
 Room 201
Poster Session 1
12:00–2:30 PM
 2nd Floor Foyer
Symposia Spotlight 1: Tissue-Specific Functions of Mitochondria
2:30–4:30 PM
 Room 201
Ron Baik, Memorial Sloan Kettering/Weill Cornell Medicine
Characterizing the Dynamics of mtDNA Mutations in Human Retinal Pigment Epithelial (RPE) Cells
Mariana Borsa, University of Oxford
DamAged Memories: How Mitochondrial Inheritance Controls T Cell Diversity
Noritaka Yamaguchi, Chiba University
Mitochondrial Protein C15ORF48 is an Inducer of Thymo-autophagy that Regulates Immunotolerance
Kao Chien Chien-Han, Academia Sinica
The Interplay between Purinosomes and Mitochondria (Cardiopathy)
Jason Maynes, Hospital for Sick Children
Mitochondrial Dysfunction and Metabolic Therapies for Congenital Heart Disease
Irit Adini, Harvard Medical School, Massachusetts General Hospital
Mitochondrial Transfer Between Melanocytes and Dendritic Cells: Unveiling a Crucial Pathway in Inflammatory Response
Yen-Jung Hsu, National Taiwan University, College of Medicine
Roles of GSK3 Isoforms in Mitochondrial Quality Control of Skeletal Muscle
Xiaojing Cuili, NTU
NME3 Catalytic Function Plays a Critical Role in the Maintenance of Cerebellar Function in an Age and Gender-Dependent Manner
Coffee Available
4:30–5:00 PM
 2nd Floor Foyer
Mitochondrial Import and Export
5:00–7:00 PM
 Room 201
Sarah Hassdenteufel, Weizmann Institute of Science
Non-Canonical Mechanisms of Protein Targeting to Mitochondria
Lena Ho, Duke-NUS Medical School
Regulation of Oxidative Metabolism by Mitochondrial Microproteins
Rebecca Voorhees, California Institute of Technology
Insertion of Tail-Anchored Proteins into Mitochondria
Soni Deshwal, Helmholtz-Munich
Short Talk: Unveiling Pathways that Dictate Mitochondrial CoQ Export and Their Role in Ferroptosis
Nora Kory, Harvard T.H Chan School of Public Health
Short Talk: TRANSIT – A New Approach to Identifying Mitochondrial Transporters
On Own for Dinner
7:00–8:00 PM
Wednesday, January 15, 2025
Breakfast
7:30–8:30 AM
 Individual Hotel
Poster Setup
8:00–8:30 AM
 2nd Floor Foyer
Poster Viewing
8:15–5:00 PM
 2nd Floor Foyer
Tissue-Specific Mitochondrial Dysfunction
8:30–11:30 AM
 Room 201
Ying Liu, Peking University
Mitochondria in Intertissue Communication in Aging and Disease
Aleksandra Filipovska, Harry Perkins Institute of Medical Research
Lipid-Mediated Organization of Mitochondrial Interactions in 3D
Aleksandra Trifunovic, University of Cologne
Taming Mitochondrial Stress Responses
Chantell S Evans, Duke University School of Medicine
Mitochondrial Quality Control in the Nervous System
Fabian Finger, University of Cologne
Short Talk: Mitochondrial Membrane Lipid CL Controls Fiber-type Adaptations in Aging Muscle via ERRγ
Katsu Funai, University of Utah
Short Talk: Cardiolipin Deficiency Disrupts Electron Transport Chain to Induce Steatohepatitis
Coffee Break
9:30–9:50 AM
 2nd Floor Foyer
Lunch
11:30–12:30 PM
 Room 201
Poster Session 2
12:00–2:30 PM
 2nd Floor Foyer
Career Roundtable
3:00–4:30 PM
 Room 201
Coffee Available
4:30–5:00 PM
 2nd Floor Foyer
Mitochondria in Immunity and Infection
5:00–7:00 PM
 Room 201
Gerald S. Shadel, The Salk Institute for Biological Studies
Mitochondria are Genotoxic Sensors
Ping-Chih Ho, Ludwig Institute for Cancer Research
Mitochondrial Catastrophes and T Cell Exhaustion: Lessons can be Applied in CAR T Cell Therapy
Lena Pernas, University of California, Los Angeles and Max Planck Institute for Biology of Ageing
'Mitochondria-Microbe Conflict
Yasmine T Toudji, Vanderbilt University
Short Talk: Differential Adaptative Responses of T Cells to Mild Heat Stress
Yentli E Soto Albrecht, U of Pennsylvania Perelman School of Medicine, Children's Hosp of Philadelphia
Short Talk: Mitochondrial OXPHOS Restricts SARS-CoV-2 Replication by Limiting Glycolytic Capacity
On Own for Dinner
7:00–8:00 PM
Thursday, January 16, 2025
Breakfast
7:30–8:30 AM
 Individual Hotel
Targeting Mitochondrial Disease
8:30–11:30 AM
 Room 201
Pénélope Andreux, Vandria SA
Mitophagy-Targeting Therapies
Anne N Murphy, Cytokinetics, Inc.
Therapeutic Discovery for Cardiac Dysfunction: Where Energy Metabolism and Signaling Harmonize
Johan Auwerx, École Polytechnique Fédérale de Lausanne
Ceramide de novo Synthesis Links Degenerative Disorders with Mitochondrial and Protein Homeostasis
Luca Scorrano, University of Padova
Unbiased Screenings for Mitochondrial Membrane Contact Sites and Mitochondrial Fission Regulators
Oliver Rackham, Curtin University
Short Talk: How a Cytoplasmic Protein Causes Mitochondrial Disease
Sean P Curran, University of Southern California
Short Talk: RNA Editing in Response to Mitochondrial Dysfunction Drives Accelerated Aging
Coffee Break
9:30–9:50 AM
 2nd Floor Foyer
On Own for Lunch
11:30–2:30 PM
Symposia Spotlight 2: Mitochondria from Bacteria to Endosymbiont
2:30–4:30 PM
 Room 201
Alexandre Smirnov, University of Strasbourg, CNRS
Ancestral Ribosome Assembly Mechanisms: From Bacteria to Mitochondria (and Beyond)
Cristiana Zollo, University of Cologne
The “Mitoscanner”: Endogenous DRP1 Continuously Scans Mitochondria in a Diffusive Manner Beyond the Fission Site
Chieh-Ju Sung, National Taiwan University
Evolutionary Conservation of Cardiolipin Externalization in Stressed Mitochondrial Revealed by Novel Bio-probe
Suzuka Ono, Kyoto Sangyo University
ATPases Control the Intracellular Distribution of Single-pass Membrane Proteins
Sofia La Vecchia, Rutgers University
Targeting Mitochondrial Dynamics In Drug-Resistant Acute Leukemia
N Sushma Sri †, Dr. Reddy's Institute of Life Sciences
Mitochondrial Dysfunction Due to PISD Loss Leads to Skeletal Phenotypes in Spondyloepimetaphyseal Dysplasia
Feng-Yung Wang, National Yang-Ming Chiao Tung University
Mitochondrial S-adenosylmethionine Deficiency Induces Mitochondrial Unfolded Protein Response and Extends Lifespan in Caenorhabditis Elegans
Xiaoai Lyu, New York University Shanghai
Surveillance of Aneuploidy by Mitochondrial Oxidative Stress Signaling Pathway
Coffee Available
4:30–5:00 PM
 2nd Floor Foyer
Non-Canonical Mitochondrial Compartments
5:00–6:45 PM
 Room 201
Johannes Herrmann, University of Kaiserslautern
Sequesteration of Mitochondrial Proteins into MitoStores
Samantha C. Lewis, University of California, Berkeley
Interdependencies Between Mitochondrial DNA and RNA Maintenance
Julien Prudent, University of Cambridge
Vesicular Release of mtDNA Drives Innate Immunity
Naotada Ishihara, Osaka University
Short Talk: Dynamic Regulation of Mitochondrial Nucleoids by Inner-membrane Components and Proteins
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
 Room 201
Social Hour with Lite Bites
7:00–8:00 PM
 Room 201
Trivia
8:00–9:00 PM
 Room 201
Friday, January 17, 2025
Departure
12:00–11:59 PM

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