Joint with: Organoids: Engineering Innovative Approaches for Basic and Translational Insight
Single Cell Biology: Unique Cells to Tissue Ecosystems

May 11–14, 2025 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers: Jose Ordovas-Montanes, Chrysothemis Brown, Karin Pelka and Jeffrey Moffitt

  In Person
  On Demand

May 11–14, 2025 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers: Jose Ordovas-Montanes, Chrysothemis Brown, Karin Pelka and Jeffrey Moffitt

Available Formats:   = In Person     = On Demand
Sunday, May 11, 2025
Registration
4:00–8:00 PM
 Macdonald Foyer
Welcome Mixer
6:00–8:00 PM
 Macdonald Foyer
Monday, May 12, 2025
Breakfast
7:00–8:00 AM
 Woodlands Terrace
Poster Setup
7:30–8:00 AM
 Macdonald EF
Poster Viewing
7:30–5:00 PM
 Macdonald EF
Welcome and Keynote Session (Joint)
8:00–9:30 AM
 Macdonald ABCD
Matthew F Krummel, University of California, San Francisco
Tissue Archetypes Across Space and Time
Gordana V Vunjak-Novakovic, Columbia University
Tissue Engineering
Coffee Break
9:30–9:50 AM
 Macdonald Foyer
High-Throughput Approaches to Model Cells and Tissues (Joint)
9:50–11:30 AM
 Macdonald ABCD
Dana Pe'er, Memorial Sloan Kettering Cancer Center
Plasticity in the Tissue Context
David Van Valen, Caltech
High-Throughput Organoid Phenotyping
Rong Fan, Yale School of Medicine
Spatial Multi-Omics Profiling of Human Tissues and Organoids
Short Talk(s) Chosen from Abstracts
Lunch
11:30–12:30 PM
 Woodlands Terrace
Poster Session 1
12:00–2:30 PM
 Macdonald EF
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
 Macdonald AB
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
 Macdonald Foyer
Biologically-Motivated Analytical Methods to Deconstruct Tissues
5:00–7:00 PM
 Macdonald AB
Holger Heyn, CNAG-CRG
Novel Cell Types and New Insights Derived from Human Lymphoid Tissue
Ricardo Ramirez, European Bioinformatics Institute
Knowledge-Based Computational Approaches to Dissect Multi-Cellular Programs from Single-Cell and Spatial Data
Peter V. Kharchenko, Altos Labs
Downstream Impact of Segmentation Errors in Spatial Analysis
Karin Pelka, Gladstone Institutes and University of California, San Francisco
Spatially Organized Multicellular Immune Hubs
Short Talk(s) Chosen from Abstracts
On Own for Dinner
7:00–8:00 PM
Tuesday, May 13, 2025
Breakfast
7:00–8:00 AM
 Woodlands Terrace
Learning from Human and Animal Variation
8:00–11:00 AM
 Macdonald AB
Monique van der Wijst, University Medical Center Groningen, UMCG
Lessons Learned from the Single-Cell eQTL Consortium
Jose Ordovas-Montanes, Boston Children's Hospital and Harvard Medical School
Charting Inflammatory Disease Trajectories in Human Barrier Tissues
Aki Minoda, RIKEN Center for Life Science Technologies
Mukin Mouse Ageing Atlas: How Microbiota affects Ageing
Paul G. Thomas, St. Jude Children's Research Hospital
Genetic and Infectious Drivers of Human Immune Variation
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
 Macdonald Foyer
Poster Setup
11:00–1:00 PM
 Macdonald EF
On Own for Lunch
11:00–3:00 PM
Poster Viewing
1:00–10:00 PM
 Macdonald EF
Career Roundtable (Joint)
1:30–2:45 PM
 MacDonald CD
Health Equity Forum (Joint)
3:00–4:30 PM
 MacDonald CD
Coffee Available
4:30–5:00 PM
 Macdonald Foyer
New Biology of Cell Types, Subsets, States and Clones
5:00–7:00 PM
 Macdonald AB
Andreas Moor, ETH
Systematic Perturbation of Cellular Interactions in the Tumor Microenvironment
Andrew RJ Lawson †, Wellcome Sanger Institute
Talk Title to be Announced
Chrysothemis Brown, Sloan Kettering Institute
Novel Antigen Presenting Cells in Early Life Immune Tolerance
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
 Woodlands Terrace
Poster Session 2
7:30–10:00 PM
 Macdonald EF
Wednesday, May 14, 2025
Breakfast
7:00–8:00 AM
 Woodlands Terrace
From Community-Engaged Research to Drug Discovery
8:00–11:00 AM
 Macdonald AB
Sara Suliman, University of California, San Francisco
Community-Based Single-Cell Research
Monkol Lek, Yale School of Medicine
Patient-Partnered Single-Cell Research to Understand Rare Musculoskeletal Disease
Shannon J Turley, Genentech, Inc.
Targeting Fibroblasts in Human Disease
Quin Wills, Ochre Bio
First Human Perturb-seq Experiments in Human Tissues and Organs
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
 Macdonald Foyer
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
 Macdonald AB
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
 Macdonald Foyer
Ex Vivo and In Vivo Reconstruction of Tissues
5:00–6:45 PM
 Macdonald AB
Alex K. Shalek, Massachusetts Institute of Technology
From Correlation to Causation: Improving Human Disease Representation in vitro for Functional Testing of in vivo-Derived Hypotheses
Chris Tape, University College London
Single-Cell Phenoscaping of Tumour Microenvironment Organoids
Jeffrey Moffitt, Boston Children's Hospital
The Role of Spatial Organization in the Gut-Microbiome Interface in Gut Inflammation
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
 Macdonald AB
Social Hour with Lite Bites
7:00–8:00 PM
 Woodlands Terrace
Entertainment
8:00–9:00 PM
Cash Bar
8:00–9:00 PM
Thursday, May 15, 2025
Departure
12:00–11:59 PM

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