Joint with: Machine Learning Applied to Macromolecular Structure and Function
Imaging Biomolecules Across Scales: From Atoms to Tissues
March 23-26, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Elizabeth Villa, Bridget Carragher and Ilaria Testa
In Person
On Demand
March 23-26, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Elizabeth Villa, Bridget Carragher and Ilaria Testa
Available Formats:
In Person
On Demand
Supported by the Directors' Fund
Available Formats: = In Person = On Demand
Fundraising
Booking Function
Sunday, March 23, 2025
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Monday, March 24, 2025
Breakfast
7:00–8:00 AM
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Wolfgang P. Baumeister, Max Planck Institute of Biochemistry
Cryo-Electron Tomography or the Power of Seeing the Whole Picture
Cryo-Electron Tomography or the Power of Seeing the Whole Picture
Machine Learning for Protein Structure (Joint)
9:00–11:15 AM
Hannah Wayment-Steele, Brandeis University
Have Protein Language Models Learned Dynamics
Have Protein Language Models Learned Dynamics
Sergey Ovchinnikov, Massachusetts Institute of Technology
Hacking AlphaFold to Do New Things
Hacking AlphaFold to Do New Things
Mohammed AlQuraishi, Columbia University
Understanding How AlphaFold Learns
Understanding How AlphaFold Learns
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
Poster Viewing
1:00–10:00 PM
Workshop 1: Orthogonal Technologies
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Structure Determination of Challenging Complexes in vitro and in situ
5:00–7:00 PM
Lori A. Passmore, MRC Laboratory of Molecular Biology
Mechanistic Insight into Polyadenylation of Eukaryotic mRNAs
Mechanistic Insight into Polyadenylation of Eukaryotic mRNAs
Dimitry Tegunov, Genentech
Enabling High-Resolution Structure Determination In Situ
Enabling High-Resolution Structure Determination In Situ
Speaker to be to be Announced
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Tuesday, March 25, 2025
Breakfast
7:00–8:00 AM
CryoET/EM and Machine Learning (Joint)
8:00–11:00 AM
Bridget Carragher, Chan Zuckerberg Imaging Institute
Making Cryo-ET Faster, Better, Cheaper
Making Cryo-ET Faster, Better, Cheaper
Bronwyn Lucas, University of California, Berkeley
Single Molecule Localization and Structure Probing in Cells
Single Molecule Localization and Structure Probing in Cells
Elizabeth Villa, University of California, San Diego
Discovering New Biology with Cryo-ET
Discovering New Biology with Cryo-ET
Elizabeth Kellogg, St. Jude Children's Research Hospital
Structural Insights into CRISPR-Based Genome Editing
Structural Insights into CRISPR-Based Genome Editing
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable (Joint)
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
The Big Picture: Capturing Events with Large-Volume EM and CLEM
5:00–7:00 PM
Jennifer A. Lippincott-Schwartz, HHMI Janelia Research Campus
Looking Under the Hood of Cells: From Simple Molecule Dynamics to Whole Cell Organelle Reconstructions
Looking Under the Hood of Cells: From Simple Molecule Dynamics to Whole Cell Organelle Reconstructions
Virginie Hamel, University of Geneva
Unveiling the Architecture of the Cell by Combining cryoET and Ultrastructure Expansion Microscopy
Unveiling the Architecture of the Cell by Combining cryoET and Ultrastructure Expansion Microscopy
Speaker to be to be Announced
Speaker from Industry
Speaker from Industry
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, March 26, 2025
Breakfast
7:00–8:00 AM
Light Microscopy Comes to Structure
8:00–11:00 AM
Eric Mulhall, The Scripps Research Institute
Linking the Structure, Mechanics, and Function of PIEZO Ion Channels with Fluorescence Nanoscopy
Linking the Structure, Mechanics, and Function of PIEZO Ion Channels with Fluorescence Nanoscopy
Joerg Bewersdorf, Yale University
All-Optical Super-Resolution Imaging of Molecules in Their Nanoscale Cellular Context
All-Optical Super-Resolution Imaging of Molecules in Their Nanoscale Cellular Context
Francisco Balzarotti, Research Institute for Molecular Pathology
Accessing the Nanoscale with Light Microscopy
Accessing the Nanoscale with Light Microscopy
Speaker to be to be Announced
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Workshop 2: Technological Breakthroughs
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Bringing Molecules to Life with Live Cell Imaging at High Resolution
5:00–6:45 PM
Ilaria Testa, KTH Royal Institute of Technology
Live Cell Imaging at the Molecular Nanoscale
Live Cell Imaging at the Molecular Nanoscale
Suliana Manley, École Polytechnique Fédérale de Lausanne
Mitochondrial Dynamic and Structural States Underpinning Homeostasis
Mitochondrial Dynamic and Structural States Underpinning Homeostasis
Ralf Jungmann, Max Planck Institute of Biochemistry
DNA-PAINTs, SOMAmers and Ultra-Resolution Fluorescence Localizomics of DNA, RNA and Protein Interactions
DNA-PAINTs, SOMAmers and Ultra-Resolution Fluorescence Localizomics of DNA, RNA and Protein Interactions
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Thursday, March 27, 2025
Departure
12:00–11:59 PM
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