Joint with: Obesity and Adipose Tissue
MASH Pathogenesis and Therapeutic Approaches

February 23-26, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Elizabeth K. Speliotes, Rebecca A. Taub and Hannele Yki-Järvinen

  In Person
  On Demand

February 23-26, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Elizabeth K. Speliotes, Rebecca A. Taub and Hannele Yki-Järvinen

Available Formats:   = In Person     = On Demand
Sunday, February 23, 2025
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Monday, February 24, 2025
Breakfast
7:00–8:00 AM
Welcome and Keynote Session (Joint)
8:00–9:30 AM
Jeffrey M. Friedman, Rockefeller University
Obesity Causes and Treatment: The End of the Beginning
Anna Mae Diehl, Duke University
Morphogens, Metabolism and MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
Coffee Break
9:30–9:50 AM
Genetic Insights into Body Fat Distribution and NAFLD (Joint)
10:00–11:30 AM
Elizabeth K. Speliotes, University of Michigan
Human Genetic Insights into NAFLD
Ruth J.F. Loos, University of Copenhagen
Genetics of Obesity and Body Fat Distribution
Karen L. Mohlke, University of North Carolina at Chapel Hill
Genetics and Genomics of Obesity-Associated Diseases
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
Poster Viewing
1:00–10:00 PM
Workshop 1: Ancestry
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Drivers of NASH
5:00–7:00 PM
Hannele Yki-Järvinen, University of Helsinki
PNPLA3 Mechanisms and Beyond
Xavier Revelo, University of Minnesota
Immune Mechanisms in NASH
Orian S. Shirihai, University of California, Los Angeles
Mitochondrial Biology and NASH
Harmeet Malhi, Mayo Clinic
Extracellular Vesicles in MASH: Mediators of Injury, Inflammation, and Potential Therapeutic Targets
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Tuesday, February 25, 2025
Breakfast
7:00–8:00 AM
Cellular Stress, Fibrosis and NAFLD
8:00–11:00 AM
Russell Goodman, MASSACHUSETTS GENERAL HOSPITAL
Reductive Stress and Common Pathophysiology of Metabolic Disease
Natalie J. Torok, Stanford University
Fibrosis in NAFLD and Aging
Jin Ye, UT Southwestern
MASH: The Ferroptotic Diseases
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
Poster Viewing
1:00–10:00 PM
Meet the Editors (Joint)
1:15–2:45 PM
Career Roundtable (Joint)
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Challenges and Innovations in Preclinical Disease Modeling
5:00–7:00 PM
Michele Vacca, University of Cambridge
An Unbiased Ranking of Murine Dietary Models based on their Proximity to Human Non-Alcoholic Steatohepatitis
Jacquelyn Maher, University of California, San Francisco
iPSC Modeling of Liver Disease
Ludovic Vallier, Berlin Institute of Health at Charité
Mechanisms Controlling Liver Regeneration During MASH Progression
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, February 26, 2025
Breakfast
7:00–8:00 AM
The Biology of Therapeutics for Obesity and NAFLD (Joint)
8:00–11:00 AM
Luca Lotta, Regeneron Pharmaceuticals Inc.
CIEDB, GPR75, INHBE in Obesity and NAFLD
Rebecca A. Taub, Madrigal Pharmaceuticals
Thyroid Agonist Biology and Human Effects
Ricardo J. Samms, Eli Lilly and Company
Dual Agonist Biology and Human Effects
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Workshop 2: Emerging Mechanisms
2:30–4:30 PM
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
New Non-invasive Measures of NASH/Fibrosis
5:00–6:45 PM
Quentin M. Anstee, Newcastle University
New Non-invasive Biomarkers for NASH Data from Litmus
Arun J. Sanyal, Virginia Commonwealth University Medical Center
New Non-invasive Biomarkers for NASH Data from Nimble
Speaker to be to be Announced
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Thursday, February 27, 2025
Departure
12:00–11:59 PM

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