Joint with: Obesity and Adipose Tissue
MASH Pathogenesis and Therapeutic Approaches

Feb 23–26, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Elizabeth K Speliotes, Rebecca A. Taub and Hannele Yki-Järvinen

  In Person
  On Demand

Feb 23–26, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Elizabeth K Speliotes, Rebecca A. Taub and Hannele Yki-Järvinen

Available Formats:   = In Person     = On Demand
Sunday, February 23, 2025
Registration
4:00–8:00 PM
 Van Horne Foyer
Welcome Mixer
6:00–8:00 PM
 Van Horne Foyer
Monday, February 24, 2025
Breakfast
7:00–8:00 AM
 President's Hall
Welcome and Keynote Session (Joint)
8:00–9:30 AM
 Van Horne A
Jeffrey M. Friedman, Rockefeller University
Obesity Causes and Treatment: The End of the Beginning
Anna Mae Diehl, Duke University
Morphogens, Metabolism and MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
Coffee Break
9:30–9:50 AM
 Van Horne Foyer
Genetic Insights into Body Fat Distribution and MASLD (Joint)
9:50–11:30 AM
 Van Horne A
Elizabeth K Speliotes, University of Michigan
Human Genetic Insights into MASLD
Ruth J Loos, University of Copenhagen
Genetics of Obesity and Body Fat Distribution
Karen L. Mohlke, University of North Carolina at Chapel Hill
Genetics and Genomics of Obesity-Associated Diseases
Poster Setup
11:30–1:00 PM
 Van Horne C
On Own for Lunch
11:30–2:30 PM
Poster Viewing
1:00–10:00 PM
 Van Horne C
Health Equity Forum (Joint)
2:30–4:30 PM
 Van Horne B
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Drivers of MASH
5:00–7:00 PM
 Van Horne B
Hannele Yki-Järvinen, University of Helsinki
PNPLA3 Mechanisms and Beyond
Xavier Revelo, University of Minnesota
Immune Mechanisms in MASH
Orian S Shirihai, University of California, Los Angeles
Mitochondrial Biology and MASH
Harmeet Malhi, Mayo Clinic
Extracellular Vesicles in MASH: Mediators of Injury, Inflammation, and Potential Therapeutic Targets
Social Hour with Lite Bites
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Tuesday, February 25, 2025
Breakfast
7:00–8:00 AM
 President's Hall
Cellular Stress, Fibrosis and MASLD
8:00–11:00 AM
 Van Horne B
Russell Goodman, Massachusetts General Hospital
Reductive Stress and Common Pathophysiology of Metabolic Disease
Natalie J. Torok, Stanford University
Fibrosis in MASLD and Aging
Jin Ye, UT Southwestern
MASH: The Ferroptotic Diseases
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
 Van Horne Foyer
Poster Setup
11:00–1:00 PM
 Van Horne C
On Own for Lunch
11:00–3:15 PM
Poster Viewing
1:00–10:00 PM
 Van Horne C
Career Roundtable (Joint)
1:30–3:00 PM
 Van Horne B
Meet the Editors (Joint)
3:15–4:30 PM
 Van Horne B
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Challenges and Innovations in Preclinical Disease Modeling
5:00–7:00 PM
 Van Horne B
Michele Vacca, University of Bari “Aldo Moro” and Roger Williams Institute of Hepatology
An Unbiased Ranking of Murine Dietary Models based on their Proximity to Human Metabolic Dysfunction Associated Steatohepatitis
Jacquelyn Maher, University of California, San Francisco
iPSC Modeling of Liver Disease
Carla Frau, Max Planck Institute of Molecular Genetics
Mechanisms controlling liver regeneration during MASH progression
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Wednesday, February 26, 2025
Breakfast
7:00–8:00 AM
 President's Hall
The Biology of Therapeutics for Obesity and MASLD (Joint)
8:00–11:00 AM
 Van Horne A
Luca Lotta, Regeneron Pharmaceuticals Inc.
CIEDB, GPR75, INHBE in Obesity and MASLD
Rebecca A. Taub, Madrigal Pharmaceuticals
Thyroid Agonist Biology and Human Effects
Ricardo J. Samms, Eli Lilly and Company
Dual Agonist Biology and Human Effects
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
 Van Horne Foyer
Poster Setup
11:00–1:00 PM
 Van Horne C
On Own for Lunch
11:00–2:30 PM
Poster Viewing
1:00–10:00 PM
 Van Horne C
Symposia Spotlight: Emerging Mechanisms
2:30–4:30 PM
 Van Horne B
Short Talk(s) Chosen from Abstracts
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
New Non-invasive Measures of MASH/Fibrosis
5:00–6:45 PM
 Van Horne B
Quentin M. Anstee, Newcastle University
New Non-invasive Biomarkers for MASH Data from Litmus
Sami F Qadri, University of Helsinki
Surveillance of the Liver in Type 2 Diabetes: Important but Unfeasible?
Rohit Loomba, University of California, San Diego, Salk Institute
Updates on Non-Invasive Imaging Markers for MASLD, MASH and Fibrosis
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
 Van Horne B
Social Hour with Lite Bites
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Thursday, February 27, 2025
Departure
12:00–11:59 PM

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