Joint with: Human Microbiome: Diversity, Selection and Adaptation
Host-Microbe Co-Evolution in Human Health: The Microbiome-Pathobiont Continuum

Feb 18–21, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Bana Jabri, Caetano Reis e Sousa and Philippe J. Sansonetti

  In Person
  On Demand

Feb 18–21, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Bana Jabri, Caetano Reis e Sousa and Philippe J. Sansonetti

Supported by:
Available Formats:   = In Person     = On Demand
Tuesday, February 18, 2025
Registration
4:00–8:00 PM
 Van Horne Foyer
Welcome Mixer
6:00–8:00 PM
 Van Horne Foyer
Wednesday, February 19, 2025
Breakfast
7:00–8:00 AM
 President's Hall
Welcome and Keynote Address (Joint)
8:00–9:00 AM
 Van Horne A
Dan R. Littman, HHMI/New York University School of Medicine
Commensals and Pathobionts in the Gut
Coffee Break
9:00–9:30 AM
 Van Horne Foyer
Viruses Within Us
9:30–11:30 AM
 Van Horne B
George Kassiotis, The Francis Crick Institute
Endogenous Retroelements and Immunity
Luis Barreiro, University of Chicago
Exploring Evolutionary Immunogenomics: Lessons from our Ancestors and Past Pandemics
Vivien Béziat, Institut Imagine
Human Genetic Determinants of Immunity to Muco-Cutaneous Papillomavirus
Danielle E Campbell, Washington University in Saint Louis School of Medicine
Short Talk: Single-Cell Viral Tagging Identifies Novel Human Gut Bacteriophages and Bacterial Hosts Associated with Inflammatory Bowel Diseasea
Elaine Kouame †, UCSF
Short Talk: Antigen-Presenting Cells Recognizing Cell Death Modulate Immunity to Dietary Antigens During Viral Infections
Poster Setup
11:15–1:00 PM
 Van Horne C
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
 Van Horne C
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
 Van Horne B
Kevin Bonham, Tufts Medical Center
Co-Development of Gut Microbial Metabolism and Visual Neural Circuitry Over Human Infancy
Michael G Constantinides, Scripps Research
MAIT Cell Responses to Intracellular and Extracellular Pathogens Are Mediated by Distinct Antigen-Presenting Cells
Maude Jans, VIB-UGent
Colibactin-Driven Colon Cancer Requires Adhesin-Mediated Epithelial Binding
Jeannette Messer, Cleveland Clinice
A Direct Antimicrobial Function of HMGB1 That Determines Bacterial Virulence In The Gut
Christopher B. Ford, Seres Therapeutics
Pharmacokinetic (PK) and Pharmacodynamic (PD) Results From A Phase 1b Study of SER-155, An Investigational, Oral, Live Biotherapeutic Evaluated In Adults Undergoing Allogeneic Stem Cell Transplant (allo-HCT)
Patrick Schimmel, Med Uni Graz
Mechanisms of FMT Efficacy in IBD Beyond Strain Engraftment
Andrew Patterson, University of Pennsylvania
A Phylogenetic Approach to Quantification of Human Endogenous Retrovirus RNA Expression
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Microbes Within Us
5:00–7:00 PM
 Van Horne B
Salomé LeibundGut-Landmann, University of Zürich
Living with Commensal Fungi
Sophie Helaine, Harvard Medical School
Persisters Curing Infection
Emma Slack, ETH Zurich
Mechanisms the Host uses to Control the Gut Microbiota
Iliyan D Iliev, Weill-Cornell Medical College
Short Talk: Fungal Commensalism and the Co-evolution of Type 2 Immunity
Reinhard Hinterleitner, University of Pittsburgh
Short Talk: Type-2 Immune-Mediated Adaptations in Epithelial Cells in Response to Commensal Protists and Helminth Infection
Social Hour with Lite Bites
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Thursday, February 20, 2025
Breakfast
7:00–8:00 AM
 President's Hall
What is a Pathobiont? Microbial Adaptations and Host Damage (Joint)
8:00–11:00 AM
 Van Horne A
Peter J Turnbaugh, University of California, San Francisco
Harnessing the Gut Microbiome to Counteract and Predict Cancer Chemotherapy Toxicity
Purna C Kashyap, Mayo Clinic
Time to Turn the Spotlight on the Small Intestinal Microbiome
Russell E Vance, University of California, Berkeley
Mechanisms of mucosal immunity against the intracellular gut pathogen Shigella flexneri
Julie A. Segre, National Institutes of Health
Global Skin Microbiome: Insights into Urbanization and Skin Microbial Pathogens
Darryl A Abbott, University of Pittsburgh
Short Talk: Maternal Immunoglobulin a Regulates the Development of the Neonatal Microbiota and Intestinal Microbiota-Specific CD4+ T Cell Responses
Darian T Carroll, Vanderbilt University Medical Center
Short Talk: Regulation of Enterocyte Lipid Metabolism by the Microbiota-derived Metabolite, Phenyllactic Acid
Coffee Break
9:00–9:20 AM
 Van Horne Foyer
Award Recipient Acknowledgement
9:20–9:25 AM
 Van Horne A
Poster Setup
11:00–1:00 PM
 Van Horne C
On Own for Lunch
11:00–2:45 PM
Career Roundtable (Joint)
1:00–2:30 PM
 Van Horne B
Poster Viewing
1:00–10:00 PM
 Van Horne C
Panel Discussion 1: Toward Molecular Mechanisms in Microbiome Research: Insights from Genetic Systems and Co-Evolved Pathways (Joint)
2:45–4:30 PM
 Van Horne A
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Host Colonization and Co-Evolution of Host-Microbial Interactions (Joint)
5:00–7:00 PM
 Van Horne A
Maria Manuel Dias da Mota, GIMM- Gulbenkian Institute For Molecular Medicine
Inter-Kingdom Interactions Shaping Malaria Infections
Andrew L Goodman, Yale School of Medicine
Bacterial Diversity and Host Response to Medications
Melanie Blokesch, École Polytechnique Fédérale de Lausanne
When Microbes Turn Hosts: Phage Defense Evolution in Pandemic Vibrio cholerae
Clarissa Campbell, The Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM)
Short Talk: Bacterial Quorum Sensing Molecules Produced Via HdtS Homologs Affect Host T Cell Immunity In The Mammalian Gut
Gregory P Donaldson †, UCLA
Short Talk: Gut Microbiota Induce an Immunoglobulin A-DMBT1 Feedback Loop to Tune Epithelial Cycling and Tumor Risk
Social Hour with Lite Bites
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Friday, February 21, 2025
Breakfast
7:00–8:00 AM
 President's Hall
Role of Gut Microbiota in Disease
8:00–11:00 AM
 Van Horne B
Michael A. Fischbach, Stanford University
Discovery and Engineering of the Antibody Response to a Prominent Skin Commensal
Pascale Vonaesch, University of Lausanne
The Gut Ecosystem in Childhood Undernutrition
Bana Jabri, University of Chicago
Intestinal Barrier, Commensals and Immunopathology
Arushana A Maknojia, Baylor College of Medicine
Short Talk: Gut-bone marrow crosstalk: How microbiota-derived signals regulate steady-state hematopoiesis?
Fanny Matheis, New York University School of Medicine
Short Talk: Rewilding of Laboratory Mice Defines a “Microbiometer,” Reveals Major Loss of Bacterial Density and Fungal Invasion, and Improves Pathogen Resistance-Associated Innate Immunity
Kali M. Pruss, Washington University School of Medicine, St. Louis
Short Talk: Effects Of Intergenerational Transmission of Small Intestinal Bacteria Cultured From Stunted Bangladeshi Children With Enteropathy
Wataru Ebina, NYU Langone Health
Short Talk: Enteric Murine Norovirus Infection Enhances Immune Checkpoint Inhibitor Treatment Of Distal Tumor
Coffee Break
9:00–9:20 AM
 Van Horne Foyer
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Interface of Nutrition, Microbiome and Disease
2:30–4:30 PM
 Van Horne B
Mohammad Arifuzzaman, Weill Cornell Medicine
Co-Evolution With Gut Microbiota: Host Metabolism Balances Microbial Regulation Of Bile Acid Signaling
Hyunji Park, POSTECH
Gut Microbial Production of Imidazole Propionate Drives Parkinson’s Pathologies
Sean Spencer, Stanford University
Capsule-Based Sampling of the Human Small Intestine Enables Rational Design of Therapeutic Bacterial Consortia for Precision Modulation of Small Intestinal Microbiota
Hallie Avalos, Vanderbilt
Salmonella Typhimurium Relies on Vitamin C Utilization for Expansion During Intestinal Inflammation
Hyoung-Soo Cho, Harvard Medical School
Colonization with Fusobacterium Remodels the Intestinal Epithelium of the Host
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Therapeutic Lessons from Bugs
5:00–6:30 PM
 Van Horne B
Ramnik Xavier, Massachusetts General Hospital
Learning Mucosal Immunity from Gut Bugs
Caetano Reis e Sousa, Francis Crick Institute
Micronutrients, the Microbiome and Cancer Immunity
Marlies Meisel, University of Pittsburgh
Metabolism, Microbiota and Cancer Immunity
Closing Keynote Address
6:30–7:15 PM
 Van Horne B
Wendy S. Garrett, Harvard School of Public Health
Interplay Between the Gastrointestinal Immune System and the Gut Microbiota in Health and Disease
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
 Van Horne B
Social Hour with Lite Bites
7:00–8:00 PM
 President's Hall
Trivia!
8:15–9:15 PM
 Van Horne A
Saturday, February 22, 2025
Departure
12:00–11:59 PM

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