Joint with: Trajectories to Heart Failure: Immunometabolic Mechanisms
Immunometabolism in Tissue Homeostasis and Diseases
Feb 10–13, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Ping-Chih Ho, María Mittelbrunn and Stanley Huang
In Person
On Demand
Feb 10–13, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Ping-Chih Ho, María Mittelbrunn and Stanley Huang
Available Formats:
Supported by:
In Person
On Demand
Available Formats: = In Person = On Demand
Merchandise Options
Registration Options
Monday, February 10, 2025
Fundraising
Booking Function
Registration
4:00–8:00 PM
Longs Peak Foyer
Welcome Mixer
6:00–8:00 PM
Longs Peak Foyer
Tuesday, February 11, 2025
Breakfast
7:00–8:00 AM
Quandary Peak
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Grays/Longs Peak
* María Mittelbrunn, Molecular Biology Center, CSIC
* Joseph A. Hill, University of Texas Southwestern Medical Center
Kathryn J Moore, New York University Medical Center
Immunometabolism in Cardiovascular Disease
Immunometabolism in Cardiovascular Disease
Immunometabolism in Heart Failure and Vascular Diseases (Joint)
9:00–11:30 AM
Grays/Longs Peak
* Ronald J Vagnozzi, University of Colorado Anschutz Medical Campus
Chiara Giannarelli, NYU Grossman School of Medicine
Immune Mechanisms of Vascular Disease
Immune Mechanisms of Vascular Disease
Kathleen Martin, Yale School of Medicine
Novel Smooth Muscle Mechanisms in Transplant Vasculopathy
Novel Smooth Muscle Mechanisms in Transplant Vasculopathy
Xing Li Wang, Fosun Pharma
Challenges and Opportunities for Cardiovascular Drug Development
Challenges and Opportunities for Cardiovascular Drug Development
Esther Lutgens, Mayo Clinic
Co-Stimulatory Immune Checkpoints: Maintaining Immune Cell Homeostasis
Co-Stimulatory Immune Checkpoints: Maintaining Immune Cell Homeostasis
Coffee Break
9:30–9:50 AM
Longs Peak Foyer
Award Recipient Acknowledgement
9:50–9:55 AM
Grays/Longs Peak
Poster Setup
11:30–1:00 PM
Quandary Peak
On Own for Lunch
11:30–5:00 PM
Poster Viewing
1:00–10:00 PM
Quandary Peak
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Immunometabolism in Tissue and Systemic Aging
5:00–7:00 PM
Longs Peak
Katrin Andreasson, Stanford University
Declining Immune Metabolism Promotes Age-Associated Inflammation and Cognitive Decline
Declining Immune Metabolism Promotes Age-Associated Inflammation and Cognitive Decline
María Mittelbrunn, Molecular Biology Center, CSIC
T Cell Metabolism in Inflammaging and Senescence
T Cell Metabolism in Inflammaging and Senescence
Marcia C. Haigis, Harvard Medical School
Immunometabolic Modulations, Aging, and Diet in Orchestating Immune Responses in the TME
Immunometabolic Modulations, Aging, and Diet in Orchestating Immune Responses in the TME
* Mariana Borsa, University of Oxford
DamAged Memories: How Autophagy-Dependent Mitochondrial Inheritance Controls T Cell Fate Decisions.
DamAged Memories: How Autophagy-Dependent Mitochondrial Inheritance Controls T Cell Fate Decisions.
Jue Feng, Icahn School of Medicine at Mount Sinai
Short Talk: Haplodeficiency of the Mtap/Cdkn2 Locus Drives Immunometabolic Dysregulation And Stromal Cell Alterations Leading To Myelodysplastic Syndromes-Like Disease
Short Talk: Haplodeficiency of the Mtap/Cdkn2 Locus Drives Immunometabolic Dysregulation And Stromal Cell Alterations Leading To Myelodysplastic Syndromes-Like Disease
Social Hour with Lite Bites
7:00–8:00 PM
Quandary Peak
Women in Science Networking Event
7:00–8:00 PM
Quandary Peak Foyer
* Gemma A Figtree, Kolling Institute, University of Sydney
Session Chair
Session Chair
* Esther Lutgens, Mayo Clinic
Session Chair
Session Chair
* Pilar Alcaide, Tufts University School of Medicine
Session Chair
Session Chair
* Kathryn E. Wellen, University of Pennsylvania
Session Chair
Session Chair
* Chiara Giannarelli, NYU Grossman School of Medicine
Session Chair
Session Chair
* María Mittelbrunn, Molecular Biology Center, CSIC
Session Chair
Session Chair
* Marlies Meisel, University of Pittsburgh
Session Chair
Session Chair
Poster Session 1
7:30–10:00 PM
Quandary Peak
Wednesday, February 12, 2025
Breakfast
7:00–8:00 AM
Quandary Peak
Immunometabolism in Cancer Immunology and Immunotherapy
8:00–11:00 AM
Longs Peak
Jonathan D. Powell, Calico Life Sciences
Metabolic Targeting for Cancer Immunotherapy
Metabolic Targeting for Cancer Immunotherapy
Stanley Huang, The Ohio State University
Amino Acid Metabolism and UPR Responses in Macrophage Immunity
Amino Acid Metabolism and UPR Responses in Macrophage Immunity
David Sancho, Centro Nacional de Investigaciones Cardiovasculares, CNIC
Microbiota and Host Dialogue: Mechanisms Driving Bone Marrow Training and Atherosclerosis
Microbiota and Host Dialogue: Mechanisms Driving Bone Marrow Training and Atherosclerosis
Nicole Walker, Weill Cornell Graduate School
Short Talk: Metabolic-Epigenetic Mechanisms of T Cell Dysfunction and DJ-1 Enhancements in CAR-T Therapy
Short Talk: Metabolic-Epigenetic Mechanisms of T Cell Dysfunction and DJ-1 Enhancements in CAR-T Therapy
Isabel Shen, University of California, San Francisco
Short Talk: Elucidating the Role of Metabolic Regulation in Immune Cell Composition and Function within the Tumor Microenvironment.
Short Talk: Elucidating the Role of Metabolic Regulation in Immune Cell Composition and Function within the Tumor Microenvironment.
* Gang Xin, OSU
The Neddylation Operates as A PTM Checkpoint for Regulating Metabolism in CD8+ T Cells
The Neddylation Operates as A PTM Checkpoint for Regulating Metabolism in CD8+ T Cells
Chen Yao, UT Southwestern Medical Center
Short Talk: KEAP1-NRF2 Axis Balances Stemness and Exhaustion in CD8+ T Cells
Short Talk: KEAP1-NRF2 Axis Balances Stemness and Exhaustion in CD8+ T Cells
Coffee Break
9:00–9:20 AM
Longs Peak Foyer
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:15–1:00 PM
Quandary Peak
Poster Viewing
1:00–10:00 PM
Quandary Peak
Career Roundtable (Joint)
3:00–4:30 PM
Grays Peak
James Priest, Tenaya Therapeutics
Senior Director of Cardiovascular Genetics
Senior Director of Cardiovascular Genetics
Maria Rescigno, Humanitas University
Professor, Group Leader, and Deputy Scientific Director
Professor, Group Leader, and Deputy Scientific Director
Meng-Ju Wu, University of Massachusetts Chan Medical School
Assistant Professor
Assistant Professor
Anne N Murphy, Cytokinetics, Inc.
Vice President, Scientific Affairs
Vice President, Scientific Affairs
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Immunometabolic Exposome in HFpEF (Joint)
5:00–7:00 PM
Grays/Longs Peak
* Matthew J Feinstein, Northwestern University
Edward Thorp, Northwestern University
Myeloid Metabolism in the Amplification and Resolution of Cardiac Inflammation
Myeloid Metabolism in the Amplification and Resolution of Cardiac Inflammation
Geneviève Derumeaux, INSERM U955, Université Paris-Est Creteil
HFpEF: Obesity-Induced Immuno-Inflammation
HFpEF: Obesity-Induced Immuno-Inflammation
Pilar Alcaide, Tufts University School of Medicine
Immune Crosstalk in HFpEF
Immune Crosstalk in HFpEF
Joseph A. Hill, University of Texas Southwestern Medical Center
Immuno-Metabolic Mechanisms of HFpEF
Immuno-Metabolic Mechanisms of HFpEF
Social Hour with Lite Bites
7:00–8:00 PM
Quandary Peak
Poster Session 2
7:30–10:00 PM
Quandary Peak
Thursday, February 13, 2025
Breakfast
7:00–8:00 AM
Quandary Peak
Metabolites-Guided Signaling Regulations in Immune Responses
8:00–11:30 AM
Longs Peak
Kathryn E. Wellen, University of Pennsylvania
Acetyl-CoA Metabolism in Tissue Homeostasis and Systemic Lipid Regulation
Acetyl-CoA Metabolism in Tissue Homeostasis and Systemic Lipid Regulation
Ping-Chih Ho, Ludwig Institute for Cancer Research
Heme-Mediated T Cell Exhaustion
Heme-Mediated T Cell Exhaustion
Tiffany Horng, ShanghaiTech University
Metabolite-Guided Immune Activation in Innate Immune Responses
Metabolite-Guided Immune Activation in Innate Immune Responses
Yajing Gao, University of California, Los Angeles
Short Talk: T Cell Cholesterol Transport Is A Metabolic Checkpoint That Links Intestinal Immune Responses To Dietary Lipid Absorption
Short Talk: T Cell Cholesterol Transport Is A Metabolic Checkpoint That Links Intestinal Immune Responses To Dietary Lipid Absorption
Guang Sheng Ling, University of Hong Kong
Short Talk: Hyperglycemia-Triggered Lipid Peroxidation Destabilizes STAT4 and Impairs Anti-Viral Th1 Responses in Type 2 Diabetes
Short Talk: Hyperglycemia-Triggered Lipid Peroxidation Destabilizes STAT4 and Impairs Anti-Viral Th1 Responses in Type 2 Diabetes
Julia Sauer, Boehringer Ingelheim Pharma GmbH & Co KG/ University of Constanze
Short Talk: Redox-Active Macrophages Confer Ferroptosis Protection to Bystander Cancer Cells Via IL4i1
Short Talk: Redox-Active Macrophages Confer Ferroptosis Protection to Bystander Cancer Cells Via IL4i1
* Meng-Ju Wu, University of Massachusetts Chan Medical School
R-2-Hydroxyglutarate Shapes the Tumor Microenvironment and Reveals Metabolic Vulnerabilities in Mutant IDH1 Cholangiocarcinoma
R-2-Hydroxyglutarate Shapes the Tumor Microenvironment and Reveals Metabolic Vulnerabilities in Mutant IDH1 Cholangiocarcinoma
Jordy Saravia, St. Jude Children's Research Hospital
Short Talk: Lysosomal Signaling Dictates Heterogeneous Metabolic States of Treg Cells to Limit Immunopathology
Short Talk: Lysosomal Signaling Dictates Heterogeneous Metabolic States of Treg Cells to Limit Immunopathology
Kim Rewitz, University of Copenhagen
Short Talk: Decoding the Interactions Between Gut Immune Responses and Systemic Metabolic and Behavioral Dynamics
Short Talk: Decoding the Interactions Between Gut Immune Responses and Systemic Metabolic and Behavioral Dynamics
Coffee Break
9:00–9:20 AM
Longs Peak Foyer
On Own for Lunch
11:30–4:30 PM
Dialogue with Journal Editors (Joint)
3:00–4:30 PM
Grays Peak
Joseph A. Hill, University of Texas Southwestern Medical Center
*Session Chair, Editor in Chief, Circulation
*Session Chair, Editor in Chief, Circulation
Gabriele G Schiattarella, Charité University Medical Center
*Session Chair, Associate Editor, Circulation
*Session Chair, Associate Editor, Circulation
Vesna Todorovic, Springer Nature
Chief Editor, Nature Cardiovascular Research
Chief Editor, Nature Cardiovascular Research
Bruce D. Koppelman, Cell Press
Scientific Editor, Immunity
Scientific Editor, Immunity
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Microbiota-Derived Metabolic Regulations
5:00–6:30 PM
Longs Peak
* Guang Sheng Ling, University of Hong Kong
Marlies Meisel, University of Pittsburgh
Exercise-induced microbiota metabolite enhances cancer immunotherapy efficacy
Exercise-induced microbiota metabolite enhances cancer immunotherapy efficacy
Maria Rescigno, Humanitas University
Microbiome-Guided metabolic control of cancer treatment
Microbiome-Guided metabolic control of cancer treatment
Upasana Das Adhikari, Massachusetts General Hospital/ Harvard med School
Short Talk: Immunometabolic Dysregulation in Colonic CD8+ T Cells Results In Epithelial Barrier Disruption In People With HIV On Antiretroviral Therapy
Short Talk: Immunometabolic Dysregulation in Colonic CD8+ T Cells Results In Epithelial Barrier Disruption In People With HIV On Antiretroviral Therapy
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:30–6:45 PM
Longs Peak
Social Hour with Lite Bites
6:45–8:00 PM
Quandary Peak
Entertainment
8:00–9:00 PM
Quandary Peak Foyer
Cash Bar
8:00–9:00 PM
Quandary Peak
Friday, February 14, 2025
Departure
12:00–11:59 PM
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