Joint with: Immunometabolism in Tissue Homeostasis and Diseases
Trajectories to Heart Failure: Immunometabolic Mechanisms
Feb 10–13, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Joseph A. Hill, Geneviève Derumeaux, Chiara Giannarelli and Gabriele G Schiattarella
In Person
On Demand
Feb 10–13, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Joseph A. Hill, Geneviève Derumeaux, Chiara Giannarelli and Gabriele G Schiattarella
Available Formats:
In Person
On Demand
Supported by Pfizer Inc.
Available Formats: = In Person = On Demand
Merchandise Options
Registration Options
Monday, February 10, 2025
Fundraising
Booking Function
Registration
4:00–8:00 PM
Shavano Foyer
Welcome Mixer
6:00–8:00 PM
Shavano Foyer
Tuesday, February 11, 2025
Breakfast
7:00–8:00 AM
Red Cloud/Crestone
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Torreys/Shavano
Kathryn J Moore, New York University Medical Center
Immunometabolism in Cardiovascular Disease
Immunometabolism in Cardiovascular Disease
Immunometabolism in Heart Failure and Vascular Diseases (Joint)
9:00–11:30 AM
Torreys/Shavano
Chiara Giannarelli, NYU Grossman School of Medicine
Immune Mechanisms of Vascular Disease
Immune Mechanisms of Vascular Disease
Kathleen Martin, Yale School of Medicine
Novel Smooth Muscle Mechanisms in Transplant Vasculopathy
Novel Smooth Muscle Mechanisms in Transplant Vasculopathy
Xing Li Wang, Fosun Pharma
Challenges and Opportunities for Cardiovascular Drug Development
Challenges and Opportunities for Cardiovascular Drug Development
Esther Lutgens, Mayo Clinic
Co-Stimulatory Immune Checkpoints: Maintaining Immune Cell Homeostasis
Co-Stimulatory Immune Checkpoints: Maintaining Immune Cell Homeostasis
Coffee Break
9:30–9:50 AM
Shavano Foyer
Poster Setup
11:30–1:00 PM
Red Cloud/Crestone
On Own for Lunch
11:30–2:30 PM
Poster Viewing
1:00–10:00 PM
Red Cloud/Crestone
Panel Discussion 1: Dialogue with Scientists and Physician-Scientists in Industry
2:30–4:30 PM
Torreys Peak
Coffee Available
4:30–5:00 PM
Shavano Foyer
Ischemic HFrEF
5:00–7:00 PM
Torreys Peak
Biykem Bozkurt, Baylor College of Medicine
Ischemic HFrEF: Clinical Presentation and Unmet Needs
Ischemic HFrEF: Clinical Presentation and Unmet Needs
James Priest, Tenaya Therapeutics
Modulation of Fibrosis in HFrEF
Modulation of Fibrosis in HFrEF
Zoltan Arany, University of Pennsylvania
Metabolic Substrate Switching in Ischemic HFrEF
Metabolic Substrate Switching in Ischemic HFrEF
Lena Ho †, Duke-NUS Medical School
Short Talk: Respiratory Chain Supercomplexes Protect Against Ischemic Heart Failure
Short Talk: Respiratory Chain Supercomplexes Protect Against Ischemic Heart Failure
Gregory Wyant, MGH
Short Talk: Plasmalogen Control of Peroxisome Degradation Confers Ischemic Protection
Short Talk: Plasmalogen Control of Peroxisome Degradation Confers Ischemic Protection
Social Hour with Lite Bites
7:00–8:00 PM
Red Cloud/Crestone
Poster Session 1
7:30–10:00 PM
Red Cloud/Crestone
Wednesday, February 12, 2025
Breakfast
7:00–8:00 AM
Red Cloud/Crestone
Cardiometabolic HFpEF
8:00–11:00 AM
Torreys Peak
Sanjiv Shah, Northwestern University
HFpEF: Clinical Presentations and Unmet Needs
HFpEF: Clinical Presentations and Unmet Needs
Kavita Sharma, Johns Hopkins University School of Medicine
HFpEF: Insights from Omics Approaches
HFpEF: Insights from Omics Approaches
Gabriele G Schiattarella, Charité University Medical Center
Metabolic Regulation of HFpEF
Metabolic Regulation of HFpEF
Ling Yang, University of Iowa
Short Talk: Lysosome Maintains Cardiac Immuno-metabolic Homeostasis in HFpEF
Short Talk: Lysosome Maintains Cardiac Immuno-metabolic Homeostasis in HFpEF
Ulrich Kintscher, Charité-Universitätsmedizin Berlin
Short Talk: Endothelial Deletion of Adipose Triglyceride Lipase Protects Against Heart Failure with Preserved Ejection Fraction
Short Talk: Endothelial Deletion of Adipose Triglyceride Lipase Protects Against Heart Failure with Preserved Ejection Fraction
Naoto Muraoka †, Gordian Biotechnology
Short Talk: Novel in Vivo Screen System to Identify Therapeutic Targets in Heart Failure with Preserved Ejection Fraction
Short Talk: Novel in Vivo Screen System to Identify Therapeutic Targets in Heart Failure with Preserved Ejection Fraction
Giuseppe D Norata †, University of Milan
Short Talk: PCSK9 at the Crossroad of Cardiac Metabolic Reprogramming During Hfpef
Short Talk: PCSK9 at the Crossroad of Cardiac Metabolic Reprogramming During Hfpef
Coffee Break
9:00–9:20 AM
Shavano Foyer
Poster Setup
11:00–1:00 PM
Red Cloud/Crestone
On Own for Lunch
11:00–3:00 PM
Career Roundtable (Joint)
1:00–2:30 PM
Torreys Peak
Poster Viewing
1:00–10:00 PM
Red Cloud/Crestone
Coffee Available
4:30–5:00 PM
Shavano Foyer
Immunometabolic Exposome in HFpEF (Joint)
5:00–7:00 PM
Torreys/Shavano
Edward Thorp, Northwestern University
Myeloid Metabolism in the Amplification and Resolution of Cardiac Inflammation
Myeloid Metabolism in the Amplification and Resolution of Cardiac Inflammation
Geneviève Derumeaux, INSERM U955, Université Paris-Est Creteil
HFpEF: Obesity-Induced Immuno-Inflammation
HFpEF: Obesity-Induced Immuno-Inflammation
Pilar Alcaide, Tufts University School of Medicine
Immune Crosstalk in HFpEF
Immune Crosstalk in HFpEF
Joseph A. Hill, University of Texas Southwestern Medical Center
Immuno-Metabolic Mechanisms of HFpEF
Immuno-Metabolic Mechanisms of HFpEF
Social Hour with Lite Bites
7:00–8:00 PM
Red Cloud/Crestone
Poster Session 2
7:30–10:00 PM
Red Cloud/Crestone
Thursday, February 13, 2025
Breakfast
7:00–8:00 AM
Red Cloud/Crestone
Afterload-Induced HFrEF
8:00–11:00 AM
Torreys Peak
Peter Liu, University of Ottawa Heart Institute
Coordination between Immunity, Metabolism and Microvasculature in Heart Failure: Now Reaching the Brain
Coordination between Immunity, Metabolism and Microvasculature in Heart Failure: Now Reaching the Brain
Anthony Rosenzweig, University of Michigan
Talk Title to be Announced
Talk Title to be Announced
Fady Malik, Cytokinetics Inc.
Sarcomere-Targeted Drugs
Sarcomere-Targeted Drugs
Gemma Figtree †, Kolling Institute, University of Sydney
Short Talk: Advanced Immune and Lipidomic Profiling in Humans and Chimpanzees to Unravel Novel Factors in CT-Image Defined Coronary Artery Disease Susceptibility and Resilience
Short Talk: Advanced Immune and Lipidomic Profiling in Humans and Chimpanzees to Unravel Novel Factors in CT-Image Defined Coronary Artery Disease Susceptibility and Resilience
Niranjana Natarajan †, Universitty of Pittsburgh
Short Talk: Spatial Transcriptomic Profiling of Macrophage–Fibroblast Dynamics in Heart Failure
Short Talk: Spatial Transcriptomic Profiling of Macrophage–Fibroblast Dynamics in Heart Failure
Justin H Berger, Washington University School of Medicine
Short Talk: SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice
Short Talk: SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice
Hyun Kook, Chonnam National University
Short Talk: Loss of p300/CBP-Associated Factor Aggravates Cardiac Remodeling Via Regulation Of Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 Acetylation
Short Talk: Loss of p300/CBP-Associated Factor Aggravates Cardiac Remodeling Via Regulation Of Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 Acetylation
Coffee Break
9:00–9:20 AM
Shavano Foyer
On Own for Lunch
11:00–2:30 PM
Panel Discussion 2: Dialogue with Journal Editors
2:30–4:30 PM
Torreys Peak
Coffee Available
4:30–5:00 PM
Shavano Foyer
HFrEF: Other Mechanisms
5:00–6:45 PM
Torreys Peak
Stavros G. Drakos, University of Utah
Metabolism and Myocardial Recovery in Heart Failure
Metabolism and Myocardial Recovery in Heart Failure
Daniela Carnevale, University La Sapienza in Rome
Neuroimmune Mechanisms of Cardiac Remodeling
Neuroimmune Mechanisms of Cardiac Remodeling
Adam E Mullick, Ionis Pharmaceuticals, Inc.
RNA Therapeutic Approaches for Heart Failure
RNA Therapeutic Approaches for Heart Failure
Luca Scorrano, University of Padova
Short Talk: Coordination Between Mitochondrial Dynamics and Autophagy in Heart Failure
Short Talk: Coordination Between Mitochondrial Dynamics and Autophagy in Heart Failure
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Torreys Peak
Social Hour with Lite Bites
7:00–8:00 PM
Red Cloud/Crestone
Entertainment
8:00–9:00 PM
Red Cloud/Crestone
Cash Bar
8:00–9:00 PM
Red Cloud/Crestone
Friday, February 14, 2025
Departure
12:00–11:59 PM
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