Joint with: Nucleic Acid Therapeutics and Targeted Delivery
Precision Genome Engineering: From Basic Mechanisms to Application
January 1-4, 2026 | Location to be Determined
Scientific Organizers:
Jonathan S. Weissman, Cecilia Cotta-Ramusino and Joseph Bondy-Denomy
In Person
On Demand
January 1-4, 2026 | Location to be Determined
Scientific Organizers:
Jonathan S. Weissman, Cecilia Cotta-Ramusino and Joseph Bondy-Denomy
Available Formats:
In Person
On Demand
Supported by the Directors' Fund
Available Formats: = In Person = On Demand
Booking Function
Thursday, January 1, 2026
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Friday, January 2, 2026
Breakfast
7:00–8:00 AM
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Demis Hassabis †, Google DeepMind
Alfa-fold3: A True Accelerator in an AI
Alfa-fold3: A True Accelerator in an AI
Delivery (Joint)
9:00–11:15 AM
Daniel J. Siegwart †, University of Texas Southwestern Medical Center
New LNP Modalities for Target Lung, Heart and Other Tissues
New LNP Modalities for Target Lung, Heart and Other Tissues
Michael A. Fischbach †, Stanford University
Engineered Viral-Like Particle for Targeted Delivery of Gene Editors
Engineered Viral-Like Particle for Targeted Delivery of Gene Editors
Leah R. Sabin †, Regeneron Pharmaceuticals
Antibody-AAV Targeting: Fundamental Principle Behind Achieving BBB Crossing
Antibody-AAV Targeting: Fundamental Principle Behind Achieving BBB Crossing
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
Poster Viewing
1:00–10:00 PM
Coffee Available
4:30–5:00 PM
New Editing Modality
5:00–7:00 PM
Samuel H. Sternberg †, Columbia University
CRISPR Guided Transposons
CRISPR Guided Transposons
Patrick D. Hsu †, Arc Institute | University of California, Berkeley
Bridge RNA-Directed Programmable Recombination
Bridge RNA-Directed Programmable Recombination
Erik J. Sontheimer †, University of Massachusetts Medical School
Engineering New Types of Prime Editors
Engineering New Types of Prime Editors
Cecilia Cotta-Ramusino, Tessera Therapeutics
Discovery and Application of New Gene Editing Modalities to Treat Disease
Discovery and Application of New Gene Editing Modalities to Treat Disease
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Saturday, January 3, 2026
Breakfast
7:00–8:00 AM
Intersection of Gene Editing and Machine Learning
8:00–11:00 AM
Hyongbum Henry Kim †, Yonsei University College of Medicine
Experimental and Machine Learning Approaches to Create New Genome Editing Tools
Experimental and Machine Learning Approaches to Create New Genome Editing Tools
Jonathan S. Weissman, Whitehead Institute, HHMI, and MIT
In vivo Multiple Modal Information-Rich CRISPR Screens
In vivo Multiple Modal Information-Rich CRISPR Screens
Daphne Koller †, insitro
Applications of CRISPR Screen and Machine Learning for Drug Discovery
Applications of CRISPR Screen and Machine Learning for Drug Discovery
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
Poster Viewing
1:00–10:00 PM
Coffee Available
4:30–5:00 PM
Innovating and Understanding CRISPR Tools
5:00–7:00 PM
Jennifer A. Doudna †, HHMI/University of California, Berkeley
Mechanism of CRISPR
Mechanism of CRISPR
Luke Gilbert †, University of California, San Francisco and Arc Institute
New Edigenome Editor
New Edigenome Editor
Samantha Maragh †, National institute of Standards and Technology
Standardization of off Target Metrics
Standardization of off Target Metrics
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Sunday, January 4, 2026
Breakfast
7:00–8:00 AM
Therapeutic Application
8:00–11:00 AM
Jennifer Gori †, Prime Medicine, Inc.
Application of Prime Editing to Treat Disease
Application of Prime Editing to Treat Disease
Haihua Chu †, Beam Therapeutics
Base Editing to Treat SCT
Base Editing to Treat SCT
Laura Sepp-Lorenzino †, Intellia Therapeutics
TTR Therapies
TTR Therapies
Kiran Musunuru †, University of Pennsylvania
T Cell Therapy using Gene Editing
T Cell Therapy using Gene Editing
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Coffee Available
4:30–5:00 PM
CRISPR Biology
5:00–6:45 PM
Joseph Bondy-Denomy, University of California, San Francisco
AntiCRISPR Phage Defense Against CRISPR Systems
AntiCRISPR Phage Defense Against CRISPR Systems
Rafael Pinilla Redondo †, University of Copenhagen
RNA Based Anti-CRISPRs and Type IV CRISPR “Natural Crispri” System
RNA Based Anti-CRISPRs and Type IV CRISPR “Natural Crispri” System
Elizabeth Kellogg †, St. Jude Children's Research Hospital
Mechanism of Programmable Transposases
Mechanism of Programmable Transposases
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Monday, January 5, 2026
Departure
12:00–11:59 PM
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