Joint with: Precision Genome Engineering: From Basic Mechanisms to Application
Nucleic Acid Therapeutics and Targeted Delivery
Mar 09–12, 2026 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Anastasia Khvorova, Eric Vallabh Minikel, Annemieke Aartsma-Rus and Holly Kordasiewicz
In Person
On Demand
Mar 09–12, 2026 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Anastasia Khvorova, Eric Vallabh Minikel, Annemieke Aartsma-Rus and Holly Kordasiewicz
Available Formats:
In Person
On Demand
Supported by the Directors' Fund
Available Formats: = In Person = On Demand
Monday, March 9, 2026
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, March 10, 2026
Breakfast
7:00–8:00 AM
Welcome and Keynote Session (Joint)
8:00–9:00 AM
Katalin Karikó †, BioNTech RNA Pharmaceuticals
Talk Title to be Announced
Talk Title to be Announced
Delivery (Joint)
9:00–11:15 AM
Daniel J. Siegwart †, University of Texas Southwestern Medical Center
LNP-SORT - Targeted Delivery Through Size and Charge
LNP-SORT - Targeted Delivery Through Size and Charge
Michael A. Fischbach, Stanford University
Engineered Viral-Like Particle for Targeted Delivery of Gene Editors
Engineered Viral-Like Particle for Targeted Delivery of Gene Editors
Leah R. Sabin †, Regeneron Pharmaceuticals
Antibody-AAV Targeting: Fundamental Principle Behind Achieving BBB Crossing
Antibody-AAV Targeting: Fundamental Principle Behind Achieving BBB Crossing
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Coffee Available
4:30–5:00 PM
Delivery Systems based on Conjugates, vs. Delivery Systems based on Particles Targeted Nucleic Acid Delivery
5:00–7:00 PM
Anastasia Khvorova, University of Massachusetts Medical School
Barcoded Libraries for Targeted siRNA Delivery
Barcoded Libraries for Targeted siRNA Delivery
Andrea L. Kasinski, Purdue University and LigamiR Therapeutics
Folate-miRNA Conjugates for Tumor Delivery
Folate-miRNA Conjugates for Tumor Delivery
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, March 11, 2026
Breakfast
7:00–8:00 AM
Distribution of RNA-based Drugs
8:00–11:00 AM
Steven F. Dowdy, University of California, San Diego
How to Tackle Endosomal Escape
How to Tackle Endosomal Escape
Brendon Cook †, Biogen
Studying Oligonucleotide Distribution after Intrathecal Treatment using Imaging
Studying Oligonucleotide Distribution after Intrathecal Treatment using Imaging
Shalini Andersson, AstraZeneca R&D
Oligonucleotide Biodistribution after Systemic Treatment
Oligonucleotide Biodistribution after Systemic Treatment
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable (Joint)
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
New Approaches to Extrahepatic Delivery
5:00–7:00 PM
Branden Ryu †, BIORCHESTRA
Non-Lipid Nanoparticle Carriers for Delivery of RNA Therapeutics the CNS
Non-Lipid Nanoparticle Carriers for Delivery of RNA Therapeutics the CNS
Holly Kordasiewicz †, Ionis Pharmaceuticals
Extra Hepatic Delivery of Oligonucleotides
Extra Hepatic Delivery of Oligonucleotides
Scarlett Barker †, Denali Therapeutics
Delivery of ASOs to the CNS using hTfR Antibodies
Delivery of ASOs to the CNS using hTfR Antibodies
Paula T. Hammond †, Massachusetts Institute of Technology
Nanomedicine in RNA Delivery
Nanomedicine in RNA Delivery
June Park †, siRNAgen Therapeutics
Micellar RNAi Conjugates for Extrahepatic Delivery
Micellar RNAi Conjugates for Extrahepatic Delivery
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, March 12, 2026
Breakfast
7:00–8:00 AM
Nucleic Acid Chemistry, Structure, Mechanism, Potency
8:00–11:00 AM
Hendrik Knoetgen †, F. Hoffmann-La Roche Ltd
Chemical Modifications for Improved Efficiency
Chemical Modifications for Improved Efficiency
Ken Yamada, University of Massachusetts Chan Medical School
exNA and Ionizable Motifs Towards Next Generation RNA Therapeutics
exNA and Ionizable Motifs Towards Next Generation RNA Therapeutics
Anna Marie Pyle †, Yale University
Structural Exploration of RNA Drug Function
Structural Exploration of RNA Drug Function
Punit P. Seth †, Alnylam Pharmaceuticals
Chemical Modifications of siRNA and ASOs
Chemical Modifications of siRNA and ASOs
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Coffee Available
4:30–5:00 PM
Clinical Innovation in RNA-based Drug Development
5:00–6:45 PM
Scott Schobel, VICO Therapeutics
ASO Development for Neurodegenerative Diseases
ASO Development for Neurodegenerative Diseases
Annemieke Aartsma-Rus, Leiden University Medical Center
N-of1 based ASOs
N-of1 based ASOs
Eric Vallabh Minikel, Broad Institute
Progress in PrP-Lowering Oligonucleotides for Prion Disease
Progress in PrP-Lowering Oligonucleotides for Prion Disease
Scott Johnson †, Comanche
Developing RNA Based Drugs to Address Women Needs: Story on Preeclampsia
Developing RNA Based Drugs to Address Women Needs: Story on Preeclampsia
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Friday, March 13, 2026
Departure
12:00–11:59 PM
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