Joint with: RNA Mediated Regulation of Immunity: Mechanism, Disease and Therapeutics
Non-Coding RNA Biology: New Roles and Diversity
Jan 27–30, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Sebastian Kadener, Irene Bozzoni and Luisa Cochella
In Person
On Demand
Jan 27–30, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Sebastian Kadener, Irene Bozzoni and Luisa Cochella
Available Formats:
In Person
On Demand
Available Formats: = In Person = On Demand
Monday, January 27, 2025
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Shavano Foyer
Welcome Mixer
6:00–8:00 PM
Shavano Foyer
Tuesday, January 28, 2025
Breakfast
7:00–8:00 AM
Crestone /Red Cloud
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Shavano/Torreys
V. Narry Kim, Seoul National University Institute for Basic Science
Cellular Regulation of Exogenous Rnas: from Viral Rnas to Mrna Therapeutics
Cellular Regulation of Exogenous Rnas: from Viral Rnas to Mrna Therapeutics
RNA Biology and Immune System Diseases (Joint)
9:00–11:30 AM
Shavano/Torreys
Noam Stern-Ginossar, Weizmann Institute of Science
Viral Pathogenesis and RNAs
Viral Pathogenesis and RNAs
Schraga Schwartz, Weizmann Institute of Science
Charting the Ribosomal Epitranscriptome
Charting the Ribosomal Epitranscriptome
Judy Lieberman, Boston Children's Hospital; Harvard University
RNA Therapeutics to Modulate Tumor Immunity
RNA Therapeutics to Modulate Tumor Immunity
Eric M Poeschla, UNIVERSITY OF COLORADO DENVER SCHOOL OF MEDICINE
Short Talk: ADAR1 haploinsufficiency and viral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy
Short Talk: ADAR1 haploinsufficiency and viral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy
Ignacio Ruiz Fernández, Spanish National Centre for Cardiovascular Research
Short Talk: T cell-derived miR-721 as a key player in inflammaging and age-related diseases
Short Talk: T cell-derived miR-721 as a key player in inflammaging and age-related diseases
Coffee Break
9:30–9:50 AM
Shavano Foyer
Poster Setup
11:15–1:00 PM
Crestone /Red Cloud
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Crestone /Red Cloud
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Shavano
Philippe Batut, Columbia University
Non-coding RNAs and genome organization control the dynamics of gene expression during development
Non-coding RNAs and genome organization control the dynamics of gene expression during development
Yehu Moran, Hebrew University of Jerusalem
Characterization of the antiviral RNAi in cnidarians sheds light on mechanistic evolution and diversity
Characterization of the antiviral RNAi in cnidarians sheds light on mechanistic evolution and diversity
Jazmin Morales †, Brandeis University
Investigating the Role of circMbl in Neural Function and Development
Investigating the Role of circMbl in Neural Function and Development
Joseph Rosenbluh, Monash University
Systematic loss-of-function screens identify pathway-specific functional circular RNAs
Systematic loss-of-function screens identify pathway-specific functional circular RNAs
Debraj Manna †, Indian Institute of Science
Regulation of the expression of ribosomal proteins by small downstream ORFs
Regulation of the expression of ribosomal proteins by small downstream ORFs
Jinbiao Ma †, Fudan University
Cryo-EM structures of IStron-encoded group I intron reveal molecular mechanism of antagonistic conflict with TnpB associated guide RNA
Cryo-EM structures of IStron-encoded group I intron reveal molecular mechanism of antagonistic conflict with TnpB associated guide RNA
Neve Auperin †, Pasteur Institute
Soma-to-Germline miRNA Inheritance via Yolk Promotes Stress Resilience in Progeny
Soma-to-Germline miRNA Inheritance via Yolk Promotes Stress Resilience in Progeny
Karine G Le Roch †, University of California, Riverside
Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum
Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum
Coffee Available
4:30–5:00 PM
Shavano Foyer
Non-Coding RNA and Chromatin
5:00–7:00 PM
Shavano
Mitchell Guttman †, California Institute of Technology
Talk Title to be Announced
Talk Title to be Announced
Claire Rougeulle, CNRS / Institut Curie
Non-coding RNAs Controlling X Chromosome Activity in Primates
Non-coding RNAs Controlling X Chromosome Activity in Primates
Donal O'Carroll, University of Edinburgh
Small RNAs and De Novo DNA Methylation
Small RNAs and De Novo DNA Methylation
Sylvia Erhardt †, Karsruhe Institute of Technology (KIT)
Short Talk: Locus-specific genome profiling identifies RNA modifications as a determining feature of centromeric chromatin organization
Short Talk: Locus-specific genome profiling identifies RNA modifications as a determining feature of centromeric chromatin organization
Tim Hasenbein, Technical University of Munich (TUM)
Short Talk: X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes
Short Talk: X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes
Social Hour with Lite Bites
7:00–8:00 PM
Crestone /Red Cloud
Poster Session 1
7:30–10:00 PM
Crestone /Red Cloud
Wednesday, January 29, 2025
Breakfast
7:00–8:00 AM
Crestone /Red Cloud
Post-Transcriptional Control by Non-Coding RNAs
8:00–11:00 AM
Shavano
Luisa Cochella, Johns Hopkins University School of Medicine
Quantitative microRNA-Mediated Repression in Animal Development
Quantitative microRNA-Mediated Repression in Animal Development
Joshua T Mendell, University of Texas Southwestern Medical Center
Regulation and Function of Mammalian Noncoding RNAs
Regulation and Function of Mammalian Noncoding RNAs
Andrea Ventura, Memorial Sloan Kettering Cancer Center
Non-Coding RNAs in Cancer and Development
Non-Coding RNAs in Cancer and Development
Peter Wang †, MIT
Short Talk: The Structural Basis for RNA Slicing by Human Argonaute2
Short Talk: The Structural Basis for RNA Slicing by Human Argonaute2
Mariangela Morlando †, Sapienza University of Rome
Short Talk: Functional Insights into circDlc1(2): A Key Regulator of microRNA Localization and Synaptic Translation in Neurons
Short Talk: Functional Insights into circDlc1(2): A Key Regulator of microRNA Localization and Synaptic Translation in Neurons
Martin J Simard, CHU de Québec-Université Laval Research Center
Short Talk: Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals
Short Talk: Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals
Francesca Briganti, UCSD
Short Talk: The use of miRNA for the identification of etiology specific compensatory mechanisms in heart disease
Short Talk: The use of miRNA for the identification of etiology specific compensatory mechanisms in heart disease
Coffee Break
9:00–9:20 AM
Shavano Foyer
Poster Setup
11:00–1:00 PM
Crestone /Red Cloud
On Own for Lunch
11:00–2:45 PM
Career Roundtable (Joint)
1:00–2:30 PM
Torreys 1-4
Poster Viewing
1:00–10:00 PM
Crestone /Red Cloud
Panel: Methodologies to Study Non-Coding RNAs: Standards and Best Practices
2:45–4:30 PM
Shavano
Coffee Available
4:30–5:00 PM
Shavano Foyer
Granules and RNA Localization
5:00–7:00 PM
Shavano
Irene Bozzoni, University La Sapienza, Rome
circRNA in the Control of Translation and RNA Trafficking
circRNA in the Control of Translation and RNA Trafficking
Roy R. Parker, HHMI/University of Colorado
Role of RNA in Granule Function and Structure
Role of RNA in Granule Function and Structure
Marie Laure Baudet, University of Trento
Intracellular Distribution of RNA and Association with Different Organelles
Intracellular Distribution of RNA and Association with Different Organelles
Scott G. Kennedy, Harvard Medical School
Non-Templated Addition of a G-Quadruplex Structure Marks RNA for Small RNA Production
Non-Templated Addition of a G-Quadruplex Structure Marks RNA for Small RNA Production
Social Hour with Lite Bites
7:00–8:00 PM
Crestone /Red Cloud
Poster Session 2
7:30–10:00 PM
Crestone /Red Cloud
Thursday, January 30, 2025
Breakfast
7:00–8:00 AM
Crestone /Red Cloud
Novel Functions of Non-Coding RNAs
8:00–11:00 AM
Shavano
Oliver J. Rando, University of Massachusetts Medical School
Transgeneration Inheritance by tRNA Fragments
Transgeneration Inheritance by tRNA Fragments
Christine Mayr, Memorial Sloan Kettering Cancer Center
Regulation of Protein Function by the 3’ UTR
Regulation of Protein Function by the 3’ UTR
Yunsun Nam, University of Texas Southwestern Medical Center
Structure Function Analysis of RNA Modifying Enzymes
Structure Function Analysis of RNA Modifying Enzymes
Sebastian Kadener, Brandeis University
Molecular and Physiological Functions of circRNAs
Molecular and Physiological Functions of circRNAs
Parna Saha, University of California San Francisco
Short Talk: Structural basis for the function of long noncoding RNA Pnky in neural stem cells
Short Talk: Structural basis for the function of long noncoding RNA Pnky in neural stem cells
Bodu Liu, Cold Spring Harbor Laboratory
Short Talk: A Casein Kinase 2 Interacting LncRNA Regulates Cellular Plasticity of Breast Cancer by Stabilizing c-Myc
Short Talk: A Casein Kinase 2 Interacting LncRNA Regulates Cellular Plasticity of Breast Cancer by Stabilizing c-Myc
Coffee Break
9:00–9:20 AM
Shavano Foyer
Meet the Editors
11:00–12:00 PM
Shavano
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Shavano
Yael Sarusi †, Weizmann Institute of Science
CHASERR-targeting antisense oligonucleotides boost CHD2 levels and affect mouse behavior in a model of CHD2 haploinsufficiency
CHASERR-targeting antisense oligonucleotides boost CHD2 levels and affect mouse behavior in a model of CHD2 haploinsufficiency
James A Oo, Goethe University
Long non-coding RNAs target the SWI/SNF complex to cell type-specific gene regulatory elements
Long non-coding RNAs target the SWI/SNF complex to cell type-specific gene regulatory elements
Jackson B Trotman †, University of North Carolina at Chapel Hill
Xist Repeat A Coordinates an Assembly of SR Proteins to Mediate Gene Silencing
Xist Repeat A Coordinates an Assembly of SR Proteins to Mediate Gene Silencing
Guifeng Wei, University of Oxford
N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics
N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics
Rima M. Sakhawala, National Institutes of Health
A new noncanonical biogenesis pathway generates a germline enriched miRNA family in C. elegans
A new noncanonical biogenesis pathway generates a germline enriched miRNA family in C. elegans
Takahisa Furukawa †, Osaka University
Single cell/nucleus RNA-Seq analysis revealed in vivo functional mechanisms of central nervous system-specific miR-124a in mouse development
Single cell/nucleus RNA-Seq analysis revealed in vivo functional mechanisms of central nervous system-specific miR-124a in mouse development
Chelsea Drown, University of Colorado Boulder
Investigation of MeCP2-RNA Targets in Rett Syndrome Neurodevelopmental Disorder
Investigation of MeCP2-RNA Targets in Rett Syndrome Neurodevelopmental Disorder
Coffee Available
4:30–5:00 PM
Shavano Foyer
RNA and Therapeutics (Joint)
5:00–6:45 PM
Shavano/Torreys
Jorge Henao-Mejia, University of Pennsylvania and Children's Hospital of Philadelphia
Talk Title to be Announced
Talk Title to be Announced
Oliver Rausch, STORM Therapeutics Limited
RNA Modification Targeted Therapeutics in Cancer
RNA Modification Targeted Therapeutics in Cancer
Trey Westbrook, Baylor College of Medicine
Talk Title to be Announced
Talk Title to be Announced
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Shavano/Torreys
Social Hour with Lite Bites
7:00–8:00 PM
Crestone /Red Cloud
Trivia
8:00–9:00 PM
Shavano
Cash Bar
8:00–9:00 PM
Crestone /Red Cloud
Friday, January 31, 2025
Fundraising
Departure
12:00–11:59 PM
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