Joint with: Non-Coding RNA Biology: New Roles and Diversity
RNA Mediated Regulation of Immunity: Mechanism, Disease and Therapeutics
Jan 27–30, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Uttiya Basu, Sun Hur and Noam Stern-Ginossar
In Person
On Demand
Jan 27–30, 2025 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Uttiya Basu, Sun Hur and Noam Stern-Ginossar
Available Formats:
In Person
On Demand
Available Formats: = In Person = On Demand
Monday, January 27, 2025
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Shavano Foyer
Welcome Mixer
6:00–8:00 PM
Shavano Foyer
Tuesday, January 28, 2025
Breakfast
7:00–8:00 AM
Crestone /Red Cloud
Welcome and Keynote Address (Joint)
8:00–9:00 AM
Shavano/Torreys
V. Narry Kim, Seoul National University Institute for Basic Science
Cellular Regulation of Exogenous Rnas: from Viral Rnas to Mrna Therapeutics
Cellular Regulation of Exogenous Rnas: from Viral Rnas to Mrna Therapeutics
RNA Biology and Immune System Diseases (Joint)
9:00–11:30 AM
Shavano/Torreys
Noam Stern-Ginossar, Weizmann Institute of Science
Viral Pathogenesis and RNAs
Viral Pathogenesis and RNAs
Schraga Schwartz, Weizmann Institute of Science
Charting the Ribosomal Epitranscriptome
Charting the Ribosomal Epitranscriptome
Judy Lieberman, Boston Children's Hospital; Harvard University
RNA Therapeutics to Modulate Tumor Immunity
RNA Therapeutics to Modulate Tumor Immunity
Eric M Poeschla, UNIVERSITY OF COLORADO DENVER SCHOOL OF MEDICINE
Short Talk: ADAR1 haploinsufficiency and viral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy
Short Talk: ADAR1 haploinsufficiency and viral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy
Ignacio Ruiz Fernández, Spanish National Centre for Cardiovascular Research
Short Talk: T cell-derived miR-721 as a key player in inflammaging and age-related diseases
Short Talk: T cell-derived miR-721 as a key player in inflammaging and age-related diseases
Coffee Break
9:30–9:50 AM
Shavano Foyer
Poster Setup
11:15–1:00 PM
Crestone /Red Cloud
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Crestone /Red Cloud
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Torreys 1-4
Valerie Griesche †, German Cancer Research Center (DKFZ)
Impact of Adenosine mRNA Modifications on the Immune Function of Macrophages
Impact of Adenosine mRNA Modifications on the Immune Function of Macrophages
Pedro J Batista, NCI, National Institutes of Health
Uncovering RNA-Mediated Mechanisms of Immune Evasion in HLRCC
Uncovering RNA-Mediated Mechanisms of Immune Evasion in HLRCC
Ksenia Skvortsova, Garvan Institute of Medical Research
Molecular Mechanisms Of Transient Re-activation Of The Inactive X Chromosome During Female Immune Cell Development
Molecular Mechanisms Of Transient Re-activation Of The Inactive X Chromosome During Female Immune Cell Development
Michael G Kharas, Memorial Sloan Kettering Cancer Center
RNA methylation and control of cellular fate in the blood
RNA methylation and control of cellular fate in the blood
Daniel E Whisenant, Columbia University
RNA processing mechanisms in B cell development
RNA processing mechanisms in B cell development
Amy L. Kenter †, University of Illinois College of Medicine
Long noncoding RNA may regulate V(D)J recombination on multiple levels
Long noncoding RNA may regulate V(D)J recombination on multiple levels
Claudia Ribeiro de Almeida, Babraham Institute
RNA Helicase Ddx1 Regulates Germinal Centre Selection and Affinity Maturation by Promoting Trna Ligase Activity
RNA Helicase Ddx1 Regulates Germinal Centre Selection and Affinity Maturation by Promoting Trna Ligase Activity
Alicia Gonzalez-Martin †, Autonoma University of Madrid
Regulation of B cell tolerance and autoimmunity by microRNAs
Regulation of B cell tolerance and autoimmunity by microRNAs
Coffee Available
4:30–5:00 PM
Shavano Foyer
Gene Expression Control in Infection and Immunity
5:00–7:00 PM
Torreys 1-4
Kate A Fitzgerald, University of Massachusetts Medical School
lncRNA Mediated Regulation of Innate Immunity
lncRNA Mediated Regulation of Innate Immunity
Cornelis Murre, University of California, San Diego
Transcriptional bursting in thymocyte selection
Transcriptional bursting in thymocyte selection
Sankar Ghosh, Columbia University
Identifying Novel lncRNAs Involved in Immunity, Inflammation and Disease
Identifying Novel lncRNAs Involved in Immunity, Inflammation and Disease
Stefan A. Muljo, National Institutes of Health
Regulation of inflammation by RNA-Binding Proteins
Regulation of inflammation by RNA-Binding Proteins
Social Hour with Lite Bites
7:00–8:00 PM
Crestone /Red Cloud
Poster Session 1
7:30–10:00 PM
Crestone /Red Cloud
Wednesday, January 29, 2025
Breakfast
7:00–8:00 AM
Crestone /Red Cloud
Innate Immune Sensing of Foreign RNA
8:00–11:00 AM
Torreys 1-4
Carola G. Vinuesa, Francis Crick Institute
RNA Sensors and TLRs
RNA Sensors and TLRs
Sun Hur, Harvard Medical School
Cytoplasmic dsRNA Sensors
Cytoplasmic dsRNA Sensors
Karlene A Cimprich, Stanford University
RNA/DNA Hybrids and Immune System Activators
RNA/DNA Hybrids and Immune System Activators
Jacki Heraud-Farlow, Hudson Institute of Medical Research
Short Talk: GGNBP2 regulates self-sensing of cellular double-stranded RNA following loss of ADAR1
Short Talk: GGNBP2 regulates self-sensing of cellular double-stranded RNA following loss of ADAR1
Ramin Hakami †, George Mason University
Short Talk: Small Extracellular Vesicles (sEV) Released by Cells Infected with the Cytoplasmic RNA Virus Rift Valley Fever Virus Protect against Viral Infection by Inducing RIG-I-dependent IFN-B Activation that Leads to Activation of Autophagy
Short Talk: Small Extracellular Vesicles (sEV) Released by Cells Infected with the Cytoplasmic RNA Virus Rift Valley Fever Virus Protect against Viral Infection by Inducing RIG-I-dependent IFN-B Activation that Leads to Activation of Autophagy
Michael Gantier, Hudson Institute of Medical Research
Short Talk: 2’-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism
Short Talk: 2’-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism
Qin Li †, University of Pennsylvania
Short Talk: MDA5-mediated immune response to endogenous dsRNAs as driver of type 1 diabetes
Short Talk: MDA5-mediated immune response to endogenous dsRNAs as driver of type 1 diabetes
Coffee Break
9:00–9:20 AM
Shavano Foyer
Poster Setup
11:00–1:00 PM
Crestone /Red Cloud
On Own for Lunch
11:00–5:00 PM
Career Roundtable (Joint)
1:00–2:30 PM
Torreys 1-4
Poster Viewing
1:00–10:00 PM
Crestone /Red Cloud
Coffee Available
4:30–5:00 PM
Shavano Foyer
RNA Structure, Modifications and Processing in the Immune System
5:00–7:00 PM
Torreys 1-4
Uttiya Basu, Columbia University
Pathogenic Noncoding RNA Processing in Immune and Neural Diseases
Pathogenic Noncoding RNA Processing in Immune and Neural Diseases
Rhiju Das, Stanford University
Use of Artificial Intelligence in Designing Immunogenic RNAs
Use of Artificial Intelligence in Designing Immunogenic RNAs
Chuan He, University of Chicago
m6A RNA Modification in Immune Cells
m6A RNA Modification in Immune Cells
Jayanta Chaudhuri, Memorial Sloan Kettering Cancer Center
G4 RNAs in B Cells
G4 RNAs in B Cells
Social Hour with Lite Bites
7:00–8:00 PM
Crestone /Red Cloud
Poster Session 2
7:30–10:00 PM
Crestone /Red Cloud
Thursday, January 30, 2025
Breakfast
7:00–8:00 AM
Crestone /Red Cloud
Retrotransposition and RNA Viruses
8:00–11:00 AM
Torreys 1-4
Kathleen H. Burns, Dana Farber Cancer Institute | Harvard Medical School
The Immune Impact of L1 Retrotransposons
The Immune Impact of L1 Retrotransposons
Paul J. Lehner, Cambridge Institute of Therapeutic Immunology and Infectious Disease
How HUSH Directs RNA-Mediated Epigenetic Silencing
How HUSH Directs RNA-Mediated Epigenetic Silencing
Helen Rowe, Queen Mary University of London
HUSH Complexes in L1 Silencing in Immune Cells
HUSH Complexes in L1 Silencing in Immune Cells
Max Lauring, Columbia University Medical Center
Short Talk: An Anti-Retrotransposon Silencing Mechanism Promotes Antibody Diversification
Short Talk: An Anti-Retrotransposon Silencing Mechanism Promotes Antibody Diversification
Yorgo Modis, University of Cambridge
Short Talk: Variants in the RNA Sensor MDA5 Trade Antiviral Activity for Autoimmune Protection / Structures of HUSH Domains
Short Talk: Variants in the RNA Sensor MDA5 Trade Antiviral Activity for Autoimmune Protection / Structures of HUSH Domains
Joana A Vidigal, NIH/NCI
Short Talk: AGO2 silences mobile transposons in the nucleus of quiescent immune cells
Short Talk: AGO2 silences mobile transposons in the nucleus of quiescent immune cells
Tiffany Hsu, Brigham and Women's Hospital
Short Talk: Extracellular functions of viral RNA sensor MDA5 in complex with disease-associated autoantibody
Short Talk: Extracellular functions of viral RNA sensor MDA5 in complex with disease-associated autoantibody
Coffee Break
9:00–9:20 AM
Shavano Foyer
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Torreys 1-4
Scott Alper, National Jewish Health
Myelodysplastic Syndrome-Associated Spliceosome Mutations Weaken Host Defense by compromising myeloid cell function
Myelodysplastic Syndrome-Associated Spliceosome Mutations Weaken Host Defense by compromising myeloid cell function
Susan B Carpenter †, University of California, Santa Cruz
High throughput and targeted approaches to characterize lncRNAs in macrophage biology
High throughput and targeted approaches to characterize lncRNAs in macrophage biology
Ruxiao Tian, Columbia University
A long noncoding RNA genetic risk factor of Systemic Lupus Erythematosus
A long noncoding RNA genetic risk factor of Systemic Lupus Erythematosus
Ira Fleming †, University of Colorado, Anschutz
Complementary transcriptomic methods provide alternative views of messenger RNA vaccine distribution in the murine lymph node
Complementary transcriptomic methods provide alternative views of messenger RNA vaccine distribution in the murine lymph node
Morgane Gourvest †, NYU Langone Medical Center - NYU Grossman School of Medicine
Long noncoding RNA regulation of inflammation in atherosclerosis
Long noncoding RNA regulation of inflammation in atherosclerosis
Pooja Mukherjee †, UC Berkeley
miRNA-Mediated Translational Activation and Repression During Early T Cell Activation in Jurkat Cells
miRNA-Mediated Translational Activation and Repression During Early T Cell Activation in Jurkat Cells
Ainara Castellanos-Rubio, University of Basque Country
Epitranscriptomic Regulation of Immune Response: The Role of MAPKAPK5AS1 lncRNA in IFN-γ Secretion and Autoimmune Disease Modulation
Epitranscriptomic Regulation of Immune Response: The Role of MAPKAPK5AS1 lncRNA in IFN-γ Secretion and Autoimmune Disease Modulation
Kristin Patrick, Vanderbilt University School of Medicine
Neat1 and the nuclear paraspeckle orchestrate the early innate immune response in macrophages
Neat1 and the nuclear paraspeckle orchestrate the early innate immune response in macrophages
Coffee Available
4:30–5:00 PM
Shavano Foyer
RNA and Therapeutics (Joint)
5:00–6:45 PM
Shavano/Torreys
Jorge Henao-Mejia, University of Pennsylvania and Children's Hospital of Philadelphia
Talk Title to be Announced
Talk Title to be Announced
Oliver Rausch, STORM Therapeutics Limited
RNA Modification Targeted Therapeutics in Cancer
RNA Modification Targeted Therapeutics in Cancer
Trey Westbrook, Baylor College of Medicine
Talk Title to be Announced
Talk Title to be Announced
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Shavano/Torreys
Social Hour with Lite Bites
7:00–8:00 PM
Crestone /Red Cloud
Trivia
8:00–9:00 PM
Shavano
Cash Bar
8:00–9:00 PM
Crestone /Red Cloud
Friday, January 31, 2025
Fundraising
Departure
12:00–11:59 PM
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