Fibrosis: Inflammation, Drivers, and Therapeutic Resolution
December 8-11, 2024 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers:
Valerie Horsley, Michael T. Longaker and Thomas A Wynn
In Person
On Demand
December 8-11, 2024 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers:
Valerie Horsley, Michael T. Longaker and Thomas A Wynn
Available Formats:
In Person
On Demand
Available Formats: = In Person = On Demand
Booking Function
Sunday, December 8, 2024
Registration
4:00–8:00 PM
Macdonald Foyer
Welcome Mixer
6:00–8:00 PM
Macdonald Foyer
Monday, December 9, 2024
Breakfast
7:00–8:00 AM
MacDonald CDEF
Welcome and Keynote Address
8:00–9:00 AM
Macdonald AB
Neil C. Henderson, Institute of Regeneration and Repair, University of Edinburgh
State of the Art Technologies to Study Organ Fibrosis
State of the Art Technologies to Study Organ Fibrosis
Fibroblast Heterogeneity and Fibrosis
9:00–11:15 AM
Macdonald AB
Darlene Dixon, NIEHS, National Institutes of Health
Mechanisms of Uterine Fibroids
Mechanisms of Uterine Fibroids
Florian Rieder, Cleveland Clinic
Fibroblast-Driven Mechanisms in Intestinal Fibrosis
Fibroblast-Driven Mechanisms in Intestinal Fibrosis
Rafael Kramann, RWTH Aachen University
Dissecting Mechanisms of Kidney and Heart Fibrosis Using Single Cell and Spatial Genomics
Dissecting Mechanisms of Kidney and Heart Fibrosis Using Single Cell and Spatial Genomics
Shannon J. Turley, Genentech, Inc.
Universal Fibroblasts in Tissues
Universal Fibroblasts in Tissues
Coffee Break
9:30–9:50 AM
Macdonald Foyer
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
MacDonald CDEF
Poster Viewing
1:00–10:00 PM
MacDonald CDEF
Workshop 1: Beyond the Multiome: Integrating -Omics and AI in Fibrosis Models
2:30–4:30 PM
Macdonald AB
Coffee Available
4:30–5:00 PM
Macdonald Foyer
Mechanobiology in Regulation of Fibrosis
5:00–7:00 PM
Macdonald AB
Michael T. Longaker, Stanford School of Medicine
Mechanical Signaling in Skin Fibrosis and Repair
Mechanical Signaling in Skin Fibrosis and Repair
Daniel Tschumperlin, Mayo Clinic
Mechanical Regulation of Lung Fibrosis Development
Mechanical Regulation of Lung Fibrosis Development
Jennifer Elisseeff, Johns Hopkins University
Immune-senescence Regulation of Fibrosis
Immune-senescence Regulation of Fibrosis
Social Hour with Lite Bites
7:00–8:00 PM
MacDonald CDEF
Posters
7:30–10:00 PM
MacDonald CDEF
Tuesday, December 10, 2024
Breakfast
7:00–8:00 AM
MacDonald CDEF
Inflammatory Drivers of Fibrosis
8:00–11:00 AM
Macdonald AB
Thomas A. Wynn, Pfizer
Type 2 Immunity and Macrophages in the Pathogenesis of Fibrosis
Type 2 Immunity and Macrophages in the Pathogenesis of Fibrosis
Shruti Naik, New York University Langone Health
Inflammatory Memory in Skin Regeneration
Inflammatory Memory in Skin Regeneration
Jeff Biernaskie, University of Calgary
Talk Title to be Announced
Talk Title to be Announced
Vinicio de Jesus Perez, Stanford University
Targeting Hyaluronan in Pulmonary Hypertension Associated with Lung Fibrosis: Insights from the SATURN Study
Targeting Hyaluronan in Pulmonary Hypertension Associated with Lung Fibrosis: Insights from the SATURN Study
Coffee Break
9:00–9:20 AM
Macdonald Foyer
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
MacDonald CDEF
Poster Viewing
1:00–10:00 PM
MacDonald CDEF
Career Roundtable
3:00–4:30 PM
Macdonald AB
Coffee Available
4:30–5:00 PM
Macdonald Foyer
Macrophage-Fibroblast Interactions
5:00–7:00 PM
Macdonald AB
Carla V. Rothlin, Yale University
Cell Death Mechanisms During Tissue Repair
Cell Death Mechanisms During Tissue Repair
Charlotte L. Scott, University of Ghent & VIB
Investigating Macrophage Functional Heterogeneity in the Fibrotic Liver
Investigating Macrophage Functional Heterogeneity in the Fibrotic Liver
Sabine Eming, University of Cologne
Metabolic Regulation of Macrophages in Skin Fibrosis
Metabolic Regulation of Macrophages in Skin Fibrosis
Social Hour with Lite Bites
7:00–8:00 PM
MacDonald CDEF
Posters
7:30–10:00 PM
MacDonald CDEF
Wednesday, December 11, 2024
Breakfast
7:00–8:00 AM
MacDonald CDEF
New Horizons: Resolving Fibrosis
8:00–11:00 AM
Macdonald AB
Valerie Horsley, Yale University
Cellular and Molecular Crosstalk During Fibrosis Resolution
Cellular and Molecular Crosstalk During Fibrosis Resolution
Rachel C. Chambers, University College London
Epithelial Progenitor Cells in Lung Fibrosis Resolution
Epithelial Progenitor Cells in Lung Fibrosis Resolution
Tatiana Kisseleva, University of California, San Diego
Portal Fibroblasts in Liver Fibrosis Resolution
Portal Fibroblasts in Liver Fibrosis Resolution
Coffee Break
9:00–9:20 AM
Macdonald Foyer
On Own for Lunch
11:00–5:00 PM
Workshop 2: Common Fibrosis Mechanisms: Lessons Across Tissues
2:30–4:30 PM
Macdonald AB
Coffee Available
4:30–5:00 PM
Macdonald Foyer
Clinical Innovations in Fibrosis
5:00–6:45 PM
Macdonald AB
Martin L. Decaris, Pliant Therapeutics
Development of a Dual avb1/avb6 Oral Therapeutic for PSC and IPF
Development of a Dual avb1/avb6 Oral Therapeutic for PSC and IPF
Haig Aghajanian, Capstan Therapeutics
In vivo Generated CAR T Cells Targeting Pathogenic Fibroblasts for the Treatment of Cardiac Fibrosis
In vivo Generated CAR T Cells Targeting Pathogenic Fibroblasts for the Treatment of Cardiac Fibrosis
Speaker to be to be Announced
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Macdonald AB
Social Hour with Lite Bites
7:00–8:00 PM
MacDonald CDEF
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Thursday, December 12, 2024
Fundraising
Departure
12:00–11:59 PM
Merchandise Options
Registration Options
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