Positive Strand RNA Viruses: Interdisciplinary Advances in Virology, Pathogenesis, Immunology, and Technology Development
October 21-24, 2024 | INEC Killarney Convention Centre, Killarney, KY, Ireland
Scientific Organizers:
Kizzmekia S. Corbett-Helaire, William B. Klimstra and Jolanda M. Smit
In Person
On Demand
October 21-24, 2024 | INEC Killarney Convention Centre, Killarney, KY, Ireland
Scientific Organizers:
Kizzmekia S. Corbett-Helaire, William B. Klimstra and Jolanda M. Smit
Available Formats:
In Person
On Demand
Supported by GlaxoSmithKline Biologicals
Available Formats: = In Person = On Demand
Booking Function
Monday, October 21, 2024
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
INEC Foyer
Welcome Mixer
6:00–8:00 PM
INEC Foyer
Tuesday, October 22, 2024
Breakfast
7:00–8:00 AM
Individual Hotel
Welcome and Keynote Address
8:00–9:00 AM
INEC Main Auditorium
Ted C. Pierson, NIAID, National Institutes of Health
Using Viral Pathogenesis to Inform Vaccine Development
Using Viral Pathogenesis to Inform Vaccine Development
On the Surface: Viral Attachment and Entry
9:00–11:15 AM
INEC Main Auditorium
Jolanda M. Smit, University of Groningen
Early Events in Arbovirus Infection
Early Events in Arbovirus Infection
Vidya Mangala Prasad, Indian Institute of Science
Structural insights into broadly neutralizing antibodies against dengue virus
Structural insights into broadly neutralizing antibodies against dengue virus
Jonathan Abraham, Harvard University
LDL Binding Proteins as RNA Virus Receptors
LDL Binding Proteins as RNA Virus Receptors
Shan-Lu Liu, Ohio State University
IFN-Inducible Phospholipid Scramblase 1 (PLSCR1) Differentially Modulates Viral Entry
IFN-Inducible Phospholipid Scramblase 1 (PLSCR1) Differentially Modulates Viral Entry
Coffee Break
9:30–9:50 AM
INEC Foyer
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
INEC Foyer
Poster Viewing
1:00–10:00 PM
INEC Foyer
Symposia Spotlight 1: Novel Approaches to Virus Research
2:30–4:30 PM
INEC Main Auditorium
Ramya Boddepalli, Indian Institute of Science Bangalore
Integrative Mathematical Model to Elucidate the Role of Interferon-Stimulated-Genes (Isgs) in the Innate Immune Response During Positive-Sense RNA Virus Infection
Integrative Mathematical Model to Elucidate the Role of Interferon-Stimulated-Genes (Isgs) in the Innate Immune Response During Positive-Sense RNA Virus Infection
Jonathan Burnie, Harvard T.H. Chan School of Public Health
Assessing Coronavirus Spike Epitope Accessibility on Native Virions Using Flow Virometry
Assessing Coronavirus Spike Epitope Accessibility on Native Virions Using Flow Virometry
Anastazia Jablunovsky, Penn State University
Investigating the Host Interactome and Intracellular Dynamics Of Zika Virus Genomic RNA Using a Fluorogenic Aptamer-Tag
Investigating the Host Interactome and Intracellular Dynamics Of Zika Virus Genomic RNA Using a Fluorogenic Aptamer-Tag
Patrick T Dolan, NIH-NIAID
Linking Viral Genotype to Host Cell Phenotype Using Single-Cell RNA Sequencing
Linking Viral Genotype to Host Cell Phenotype Using Single-Cell RNA Sequencing
Anna K Overby, Umeå University
Whole Brain Imaging Reveals That Both the Type I IFN System and the Structural Proteins Shape Tropism of Tick-Borne Flavivirus Within the Brain.
Whole Brain Imaging Reveals That Both the Type I IFN System and the Structural Proteins Shape Tropism of Tick-Borne Flavivirus Within the Brain.
Aarthi Narayanan, George Mason University
Optimizing a Machine Learning Strategy Towards the Development of an Artificial Intelligence Platform to Understand Host Drivers of Endothelial Damage in (Re)Emerging Viral Infections
Optimizing a Machine Learning Strategy Towards the Development of an Artificial Intelligence Platform to Understand Host Drivers of Endothelial Damage in (Re)Emerging Viral Infections
Natasha Wyndham Hanners, University of Texas Southwestern Medical Center
Shiftless-Mediated Control of Zika Virus Neuropathogenesis
Shiftless-Mediated Control of Zika Virus Neuropathogenesis
Frank van Kuppeveld †, Utrecht University
Live Cell Single-Molecule Imaging to Study the Role of Enterovirus 2A Protease in the Early Phases of Viral RNA Translation and Replication
Live Cell Single-Molecule Imaging to Study the Role of Enterovirus 2A Protease in the Early Phases of Viral RNA Translation and Replication
Coffee Available
4:30–5:00 PM
INEC Foyer
Below the Surface: Mechanisms of Viral Replication, Assembly, and Pathogenesis
5:00–7:00 PM
Margaret Kielian, Albert Einstein College of Medicine
Mechanisms of RNA Virus Entry and Transmission
Mechanisms of RNA Virus Entry and Transmission
Jan E. Carette, Stanford University
Genetic Screens Identify Host Proteins Required for Emerging Picornaviruses
Genetic Screens Identify Host Proteins Required for Emerging Picornaviruses
Stephanie Karst, University of Florida
Maternal Metabolism Determines Heightened Neonatal Susceptibility to Norovirus Disease
Maternal Metabolism Determines Heightened Neonatal Susceptibility to Norovirus Disease
Andrii Slonchak, University of Queensland
Zika Virus Noncoding RNA (Sfrna) Interacts With Viral Protein NS5 To Inhibit Antiviral Response and Promote Viral Replication and Pathogenesis
Zika Virus Noncoding RNA (Sfrna) Interacts With Viral Protein NS5 To Inhibit Antiviral Response and Promote Viral Replication and Pathogenesis
Chun-Chieh Hsu, Rutgers University
SARS-Cov-2 NSP14 Induces N7-Methylguanosine Modifications in Host and Viral RNA
SARS-Cov-2 NSP14 Induces N7-Methylguanosine Modifications in Host and Viral RNA
Cocktail Hour Sponsored by Michelson Philanthropies
7:00–8:00 PM
INEC Foyer
Dinner Lite Bites
7:15–8:15 PM
INEC Foyer
Poster Session 1
7:45–10:00 PM
INEC Foyer
Wednesday, October 23, 2024
Breakfast
7:00–8:00 AM
Individual Hotel
Host Responses to RNA Virus Infection
8:00–11:00 AM
INEC Main Auditorium
Matthew D. Daugherty, University of California, San Diego
Tripping the Wire: Innate Immune Sensing of Viral Protease Activity Through Effector-Triggered Immunity
Tripping the Wire: Innate Immune Sensing of Viral Protease Activity Through Effector-Triggered Immunity
Hadi M. Yassine, Qatar University
Immune Imprinting between Protection and Enhanced Disease
Immune Imprinting between Protection and Enhanced Disease
Suresh Mahalingam, Griffith University
Host Responses and Pathogenesis of Acute and Chronic Chikungunya Infection
Host Responses and Pathogenesis of Acute and Chronic Chikungunya Infection
Ana Fernandez-Sesma, Icahn School of Medicine at Mount Sinai
Innate Immune Modulation by Arboviruses
Innate Immune Modulation by Arboviruses
Katherine Barnett, University of North Carolina at Chapel Hill
Cell Death, Damage, and Inflammation in SARS-Cov-2 Infection
Cell Death, Damage, and Inflammation in SARS-Cov-2 Infection
Tulika Singh, University of California, Berkeley
Striking Differences in Pediatric Dengue Virus B Cell And Antibody Imprinting Based on Prior Flavivirus Infection
Striking Differences in Pediatric Dengue Virus B Cell And Antibody Imprinting Based on Prior Flavivirus Infection
Coffee Break
9:00–9:20 AM
INEC Foyer
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
INEC Foyer
Poster Viewing
1:00–10:00 PM
INEC Foyer
Career Roundtable
3:00–4:30 PM
INEC Main Auditorium
Coffee Available
4:30–5:00 PM
INEC Foyer
The Structure/Function Relationship
5:00–7:00 PM
INEC Main Auditorium
Dahai Luo, Nanyang Technological University
Molecular Architecture of the CHIKV Replication Complex
Molecular Architecture of the CHIKV Replication Complex
James E. Crowe, Jr., Vanderbilt University Medical Center
Human Monoclonal Antibodies for Prevention and Treatment of Positive Strand RNA Viruses
Human Monoclonal Antibodies for Prevention and Treatment of Positive Strand RNA Viruses
Shee Mei Lok, Duke-NUS Medical School
Tomography Studies of the Dengue Fusion Process
Tomography Studies of the Dengue Fusion Process
Paige D Hall, Washington University in St. Louis
Cryo-EM Structure Of Mature Human Astrovirus In Complex With Neonatal Fc Receptor
Cryo-EM Structure Of Mature Human Astrovirus In Complex With Neonatal Fc Receptor
Matthew Sutton, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Potent Vaccine-Elicited Mabs: Structural Basis for Broad Protection Against Alphaviruses
Potent Vaccine-Elicited Mabs: Structural Basis for Broad Protection Against Alphaviruses
Michelson Philanthropies Award Ceremony and Dinner
7:00–8:15 PM
INEC Foyer
Poster Session 2
8:00–10:00 PM
INEC Foyer
Thursday, October 24, 2024
Breakfast
7:00–8:00 AM
Individual Hotel
Zoonosis, Viral Evolution, and Epidemiology
8:00–11:00 AM
INEC Main Auditorium
George Fu Gao, Institute of Microbiology, Chinese Academy of Sciences
Advances in Surveillance of Emerging Viruses to Avoid a Global Pandemic
Advances in Surveillance of Emerging Viruses to Avoid a Global Pandemic
Chris Bahl, Evocast
Using AI to Predict SARS-CoV-2 Variant Evolution
Using AI to Predict SARS-CoV-2 Variant Evolution
Eva Harris, University of Califonia, Berkeley
Lessons from a Longitudinal Flavivirus Infection Cohort in Nicaragua
Lessons from a Longitudinal Flavivirus Infection Cohort in Nicaragua
Michael Letko, Washington State University
Functional Viromics of Beta-Coronavirus Entry
Functional Viromics of Beta-Coronavirus Entry
Dixitkumar Nanubhai Tandel, Centre for cellular and molecular biology
Evolutionary Tale of SARS-Cov-2 Variants from The Perspective of Host Innate Immune Response
Evolutionary Tale of SARS-Cov-2 Variants from The Perspective of Host Innate Immune Response
Coffee Break
9:00–9:20 AM
INEC Foyer
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
INEC Foyer
Poster Viewing
1:00–10:00 PM
INEC Foyer
Symposia Spotlight 2: Detecting and Preparing for Emerging Viral Threats
2:30–4:30 PM
INEC Main Auditorium
Christian K.O Dzuvor, Harvard University
Multivalent Endemic Immunodominant Domain (IDD) Nanoparticle Immunogens Induce Broadly Cross-reactive Anti-Coronavirus Responses
Multivalent Endemic Immunodominant Domain (IDD) Nanoparticle Immunogens Induce Broadly Cross-reactive Anti-Coronavirus Responses
Raul Y Sanchez-David, Blizard Institut, Queen Mary University London
Novel Strategy to Enhance Self-Amplifying mRNA's Technologies Activity in Mammalian Cells by Spatial Redistribution of the Vectors Double Stranded RNA
Novel Strategy to Enhance Self-Amplifying mRNA's Technologies Activity in Mammalian Cells by Spatial Redistribution of the Vectors Double Stranded RNA
Nicole Stark, Indiana University
The Interactive Effects of Wolbachia And Nop60B on Sindbis Virus Replication
The Interactive Effects of Wolbachia And Nop60B on Sindbis Virus Replication
Nicholas J Catanzaro, University of North Carolina at Chapel Hill
Species-Specific ACE2 Receptor Usage by The Merbecovirus HKU5: Divergence from MERS-Cov and Implications for Antiviral Strategies.
Species-Specific ACE2 Receptor Usage by The Merbecovirus HKU5: Divergence from MERS-Cov and Implications for Antiviral Strategies.
Paula Bueno Fernández, Research Center
Discovery of a Novel Coronaviral Molecular Target Through Characterization of Molecules with Pan-Coronavirus Antiviral Activity
Discovery of a Novel Coronaviral Molecular Target Through Characterization of Molecules with Pan-Coronavirus Antiviral Activity
Coffee Available
4:30–5:00 PM
INEC Foyer
The Future of Vaccines, Antibodies, and Antivirals
5:00–6:45 PM
INEC Main Auditorium
Kizzmekia S. Corbett-Helaire, Harvard T.H. Chan School of Public Health
Using Antibody Responses to Inform Universal Coronavirus Vaccine Development
Using Antibody Responses to Inform Universal Coronavirus Vaccine Development
Timothy P. Sheahan, University of North Carolina
Preparing for Tomorrow’s Pandemics Today Through the Development of Broadly Active Antivirals
Preparing for Tomorrow’s Pandemics Today Through the Development of Broadly Active Antivirals
William B. Klimstra, University of Pittsburgh
Informed Design of Live-Attenuated Alphavirus Vaccines
Informed Design of Live-Attenuated Alphavirus Vaccines
James Brett Case, Washington University School of Medicine
A Trivalent Mucosal Vaccine Encoding Phylogenetically Inferred Ancestral RBD Sequences Confers Pan-Sarbecovirus Protection in Mice
A Trivalent Mucosal Vaccine Encoding Phylogenetically Inferred Ancestral RBD Sequences Confers Pan-Sarbecovirus Protection in Mice
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
INEC Main Auditorium
Social Hour with Lite Bites
7:00–8:00 PM
INEC Foyer
Poster Session 3
7:30–10:00 PM
INEC Foyer
Friday, October 25, 2024
Fundraising
Departure
12:00–11:59 PM
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