Neurobiology of Ingestive Behavior

Apr 22–25, 2025 | Asilomar Hotel and Conference Grounds, Pacific Grove, CA, United States
Scientific Organizers: Daniela Cota, Timo D. Müller and Dana M. Small

  In Person
  On Demand

Apr 22–25, 2025 | Asilomar Hotel and Conference Grounds, Pacific Grove, CA, United States
Scientific Organizers: Daniela Cota, Timo D. Müller and Dana M. Small

Supported by:
Available Formats:   = In Person     = On Demand
Tuesday, April 22, 2025
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Wednesday, April 23, 2025
Breakfast
7:00–8:00 AM
Welcome and Keynote Address
8:00–9:00 AM
Matthias H. Tschöp, Helmholtz Munich
Multi-Receptor Drugs for Obesity: Discovery, Mechanism & Clinical Impact
CNS Mechanisms of Novel Therapies Against Obesity and Beyond
9:00–11:30 AM
Timo D. Müller, Institute for Diabetes and Obesity, Helmholtz Munich
A Novel Incretin-based Quintuple Agonist for the Treatment of Obesity and Diabetes
Julie Moyers, Eli Lilly and Company
Novel Drugs Targeting CNS Mechanisms of Body Weight Loss
Karin Conde-Knape, Novo Nordisk A/S
CNS Mechanisms of Cagrilintide-Semaglutide Combinatorial Therapy to Treat Obesity
Mafalda M.A. Pereira, Boehringer Ingelheim
Deciphering the Mechanisms of Survodutide as an Anti-Obesity Therapy
Coffee Break
9:30–9:50 AM
Poster Setup
11:30–1:00 PM
On Own for Lunch
11:30–2:30 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Research presentations selected from abstract submissions
2:30–4:30 PM
Tim Gruber, Van Andel Institute
Binge-Eating Disorder Vulnerability Is Determined By Tet1 Dosage In Midbrain Dopamine Neurons
Giulia Mazzini, University of Zurich
From Metabolism To Memory: Exploring Amylin's Physiological Role In The Hippocampus
Leontine Sandforth, Institute for Diabetes Research and Metabolic Diseases
Hippocampal Response To Central Insulin Is Reduced With Age In Females With Unhealthy Fat Distribution
Emily McGrath, UCSF
Apolipoprotein E Regulates Microglial Remodeling Of Hypothalamic Myelin In Obesity
Xinyu Yue, University of California, San Francisco
Molecular Representation Of Peripheral Energy Levels By Neuronal Cilia
Moonsun Sa, Seoul national university
Role Of Hypothalamic Gabra5 Neurons And Astrocytic Gaba In Fat Regulation And Obesity
Hallie Wachsmuth, University of Arizona
Mediobasal Hypothalamic Aryl Hydrocarbon Receptor Is Critical For Metabolic Homeostasis Via Regulation Of Hypothalamic Inflammation
Madina Sokolov, University of Michigan
Defining The Gut-Pancreas Neuronal Circuit That Controls Insulin Secretion
Coffee Available
4:30–5:00 PM
Gut-Brain Axis and Feeding Behavior
5:00–7:00 PM
Zachary A. Knight, University of California, San Francisco
Learning from Post-Ingestive Rewards
Ivan E. de Araujo, Max Planck Institute for Biological Cybernetics
The Gut-Brain Axis in Feeding Behavior
Martin G. Myers, Jr., University of Michigan
Hindbrain Circuits in the Control of Eating Behavior and Energy Balance
Nicholas Vincent DiPatrizio, University of California Riverside School of Medicine, Center for Cannabinoid Research
Short Talk: The Ups And Downs Of Brain-Gut-Brain Endocannabinoid Signaling In Food Intake And Reward
Nikolai Pirmin P Jaschke †, Yale School of Medicine
Short Talk: Gut-To-Brain Communication Protects Against Dietary Protein Toxicity During Recovery From Catabolic States
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, April 24, 2025
Breakfast
7:00–8:00 AM
Neuronal Circuits Integrating Hunger and Other Competing States
8:00–11:00 AM
Michael Krashes, NIDDK, National Institutes of Health
Brain Circuits Coordinating Survival Needs
Hyung Jin Choi, Seoul National University College of Medicine
Neural Circuits Integrating Hunger and Food Choices
Robyn M. Brown, University of Melbourne
Neural Circuits Underlying Stress-Related Eating
Heidi H Pak †, UT Southwestern
Short Talk: Habitual Feeding Schedule Enhances The Metabolic And Physiological Effects Of Calorie Restriction
Tanya Pattnaik, University of Illinois, Urbana-Champaign
Short Talk: Dopamine Signaling Regulates Feeding Behavior During Lactation In Mice
Elijah D Lowenstein, Beth Israel Deaconess Medical Center
Short Talk: A Hypothalamic Circuit For Anticipating Future Changes In Energy Balance
Yael Kuperman, Weizmann Institute
Short Talk: Disruption Of The Developmental Factor Otp In The Adult Forebrain Reveals Its Diverse Physiological Functions
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–1:00 PM
Poster Setup
11:00–1:00 PM
Career Roundtable
1:00–2:30 PM
Poster Viewing
1:00–10:00 PM
Panel Discussion: How to Fill the Gap between Academic Research and Clinical Implementation? Addressing Reproducibility, Research Standards and Translation Towards the Clinic
2:45–4:30 PM
Coffee Available
4:30–5:00 PM
Aversive and Non-Aversive Circuits of Appetite Suppression
5:00–7:00 PM
Matthew R. Hayes, University of Pennsylvania
GIP and GLP-1 Signaling in Satiety and Nausea
Stephen O'Rahilly, University of Cambridge
GDF15 in Nausea and Beyond
Laura Huckins, Yale School of Medicine
Genetic and Biological Determinants of Anorexia Nervosa
Stephan Herzig, Helmholtz Zentrum München
Cancer Cachexia: Bridging the CNS with Peripheral Wasting
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Friday, April 25, 2025
Breakfast
7:00–8:00 AM
Neuroendocrine Control of Food Intake, Body Weight and Metabolism
8:00–11:00 AM
Karine Clément, INSERM / Sorbonne Universite
Precision Medicine Approach in Patients with Melanocortin Pathway Disorders
Daniela Cota, INSERM U1215 Neurocentre Magendie
Hypothalamic Responses to Energy Surfeit in the Regulation of Energy Balance
Thomas Alexander Lutz, University of Zürich
Brain Circuits for Amylin Action
Elizabeth Godschall, University of Virginia
Short Talk: A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs
Shuke Xiao, Stanford University
Short Talk: A Postprandial Python Metabolite Mediates A Gut-Liver-Brain Feeding Axis
Mireia Montaner, University of Cambridge
Short Talk: Interactions Between Olfactory Bulb Glp-1, Sensory Perception Of Food And Feeding Behaviour
Zhenggang Zhu, UC San Diego
Short Talk: Hedonic Eating Is Controlled By Dopamine Neurons That Oppose Glp-1r Satiety
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2: Research presentations selected from abstract submissions
2:30–4:30 PM
Robert M Gutgesell, Helmholtz Center Munich
Gipr Agonism and Antagonism Decrease Body Weight and Food Intake Via Different Mechanisms of Action
Caitlin M Baumer Harrison, University of Pennsylvania
Biased Agonism Of The Glp-1r Maintains Glycemic Control Without Producing Nausea Or Emesis In Preclinical Models
Mette Ludwig, Novo Nordisk
Cross-Species Atlas Of The Dorsal Vagal Complex Reveals Neural Mediators Of Cagrilintide’s Effects On Energy Balance
Jo E Lewis, University of Cambridge
Glucose-Dependent Insulinotrophic Polypeptide Regulates Food Intake And Body Weight Via The Area Postrema In Mice
Samantha Fortin, University of Pennsylvania
Regulation Of Food Intake By The Locus Coeruleus
Han Tan, Rockefeller University
The Cellular And Molecular Basis For Leptin Regulation Of Energy Balance
Abbey Blake †, UCSF Diabetes Center
A New Crispri Approach To Investigate The Pathogenic Mechanism Of Obesity-Associated Genes
Antje Körner †, Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) at Helmholtz Munich and Leipzig University
A Novel Monogenic Agouti-Like Obesity Trait: New Insights From Mice And Men
Coffee Available
4:30–5:00 PM
Neural Substrates of Hedonic Eating and Decision Making
5:00–6:45 PM
Christian Lüscher, University of Geneva
Circuits of Hedonic Feeding in Health and Disease
Dana M. Small, McGill University and the Research Institute of the McGill University Health Center (RI-MUHC)
Diet-Induced Neural Plasticity in Food Reward and Reinforcement
Soyoung Q. Park, German Institute of Human Nutrition Potsdam-Rehbruecke
Neural Determinants of Decision Making in Feeding Behavior
Marc Tittgemeyer, Max Planck Institute for Metabolism Research
Short Talk: Intersection Of Metabolic Pathways With Circuit Mechanisms Of Sensory Learning
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Saturday, April 26, 2025
Departure
12:00–11:59 PM

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