Lipids in Cellular Function and Disease
Apr 06–09, 2025 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers:
Valerie B. O'Donnell, Junken Aoki and Vytas A. Bankaitis
In Person
On Demand
Apr 06–09, 2025 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers:
Valerie B. O'Donnell, Junken Aoki and Vytas A. Bankaitis
Available Formats:
Supported by:
In Person
On Demand
Available Formats: = In Person = On Demand
Merchandise Options
Registration Options
Sunday, April 6, 2025
Fundraising
Booking Function
Workshop on Networking & Communication Skills for Early-Career Scientists
4:00–6:00 PM
Peaks 4-5
Registration
4:00–8:00 PM
Colorado Ballroom Foyer
Welcome Mixer
6:00–8:00 PM
Colorado Ballroom Foyer
Monday, April 7, 2025
Breakfast
7:00–8:00 AM
Summit Gallery
Welcome and Keynote Address
8:00–9:00 AM
Peaks 4 - 5
Marcus Conrad, Helmholtz Zentrum München
Role of Lipids in Driving Ferroptosis in Mitochondria
Role of Lipids in Driving Ferroptosis in Mitochondria
Organelle Stress and Ferroptosis in Health and Diseases
9:00–11:15 AM
Peaks 4 - 5
Karen Reue, University of California, Los Angeles
Identification of Genes that Control Lipid Metabolism
Identification of Genes that Control Lipid Metabolism
Guillaume Thibault, Nanyang Technological University
Lipid Bilayer Stress-Induced Unfolded Protein Response in Aging
Lipid Bilayer Stress-Induced Unfolded Protein Response in Aging
James A Olzmann, University of California, Berkeley
At The Intersection of Lipid Droplets and Ferroptosis
At The Intersection of Lipid Droplets and Ferroptosis
Cyrus Nikain, MSKCC
Short Talk: IFITM3 Regulates Ferroptosis Through Membrane Remodeling
Short Talk: IFITM3 Regulates Ferroptosis Through Membrane Remodeling
Coffee Break
9:30–9:50 AM
Colorado Ballroom Foyer
Poster Setup
11:15–1:00 PM
Peaks 1 - 3
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Peaks 1 - 3
LIPID MAPS/ILS Workshop
2:30–4:30 PM
Peaks 4 - 5
Kim Ekroos, Lipidomics Consulting Ltd.
Gerhard Liebisch, University of Regensburg
Matthew Conroy, Cardiff University
Coffee Available
4:30–5:00 PM
Colorado Ballroom Foyer
Lipids in Metabolic Disease
5:00–7:00 PM
Peaks 4 - 5
Judith A. Simcox, University of Wisconsin - Madison
Regulation of Energy Expenditure by Plasma Lipid Signaling
Regulation of Energy Expenditure by Plasma Lipid Signaling
Russell A. DeBose-Boyd, University of Texas Southwestern Medical Center
Cholesterol Metabolism
Cholesterol Metabolism
L. A Cowart, Virginia Commonwealth University
Ceramide Synthases and Obesity
Ceramide Synthases and Obesity
Mehdi Damaghi, Stony Brook University
Short Talk: Sphingolipids Metabolic Plasticity Defines Cancer Cell Fitness in Adaptation to Acidic Tumor Microenvironments
Short Talk: Sphingolipids Metabolic Plasticity Defines Cancer Cell Fitness in Adaptation to Acidic Tumor Microenvironments
Robert Ahrends, University of Vienna
Short Talk: Critical Shifts In Lipid Metabolism Promote Megakaryocyte Differentiation And Proplatelet Formation
Short Talk: Critical Shifts In Lipid Metabolism Promote Megakaryocyte Differentiation And Proplatelet Formation
Social Hour with Lite Bites
7:00–8:00 PM
Peaks 1 - 3
Poster Session 1
7:30–10:00 PM
Peaks 1 - 3
Tuesday, April 8, 2025
Breakfast
7:00–8:00 AM
Summit Gallery
Role of Lipids in Organisms and Metabolic Disease
8:00–11:00 AM
Peaks 4 - 5
Dominic Campopiano, University of Edinburgh
Novel Sphingolipids Generated by Bacteria
Novel Sphingolipids Generated by Bacteria
Michael H. Gelb, University of Washington
Mass Spectrometry-Based Expansion of Newborn Screening
Mass Spectrometry-Based Expansion of Newborn Screening
Edward A. Dennis, University of California, San Diego
Specificity of Lipid Enzymes in Cellular Function and Metabolic Disease
Specificity of Lipid Enzymes in Cellular Function and Metabolic Disease
Yarden Ariav, Weizmann Institute of Science
Short Talk: Elevating cGMP Levels Through PDE5A Inhibition Restricts Cancer Metastasis By Impeding NPC1-Mediated Cholesterol Trafficking
Short Talk: Elevating cGMP Levels Through PDE5A Inhibition Restricts Cancer Metastasis By Impeding NPC1-Mediated Cholesterol Trafficking
Eugene Koo, University of Texas Southwestern Medical Center
Short Talk: Bacterial Lipopolysaccharide Stimulates Long Chain Fatty Acid Uptake in The Small Intestine
Short Talk: Bacterial Lipopolysaccharide Stimulates Long Chain Fatty Acid Uptake in The Small Intestine
Josie Daldegan Rezende, University of Maryland, Baltimore
Short Talk: Correlation Of Hepatoxicity Markers And Sphingolipid Enzymatic Activity To Sphingolipid Structure And Abundance
Short Talk: Correlation Of Hepatoxicity Markers And Sphingolipid Enzymatic Activity To Sphingolipid Structure And Abundance
Xiaoman Liu, The Broad Institute of MIT and Harvard
Short Talk: AKAP11 Dysfunction In Astrocytes: Implications For Lipid Metabolism And Neuronal Hyperexcitability In Schizophrenia And Bipolar Disorder
Short Talk: AKAP11 Dysfunction In Astrocytes: Implications For Lipid Metabolism And Neuronal Hyperexcitability In Schizophrenia And Bipolar Disorder
Coffee Break
9:00–9:20 AM
Colorado Ballroom Foyer
Poster Setup
11:00–1:00 PM
Peaks 1 - 3
On Own for Lunch
11:00–3:00 PM
Career Roundtable
1:00–2:30 PM
Peaks 4 - 5
Poster Viewing
1:00–10:00 PM
Peaks 1 - 3
Intersections between Lipid Metabolism and Ferroptosis
3:00–4:30 PM
Peaks 4 - 5
Daniela Costa, Cardiff University
Platelet-Derived Enzymatically Oxidized Phospholipids Link Coagulopathies To Systemic Inflammation In Thromboembolic Disease
Platelet-Derived Enzymatically Oxidized Phospholipids Link Coagulopathies To Systemic Inflammation In Thromboembolic Disease
Javier Garcia-Bermudez, University of Texas Southwestern Medical Center
Dissecting The Roles Of Lipid Uptake In Tumors
Dissecting The Roles Of Lipid Uptake In Tumors
Justine Mucinski, AdventHealth
Effects of 24 months of calorie restriction on circulating ceramides and associated sphingolipids in healthy adults
Effects of 24 months of calorie restriction on circulating ceramides and associated sphingolipids in healthy adults
Michele R Plewes, University of Nebraska Medical Center
Dysregulated Lipid Metabolism and SREBP1/2 Signaling Contribute to Granulosa Cell Dysfunction and Impaired Ovarian Response
Dysregulated Lipid Metabolism and SREBP1/2 Signaling Contribute to Granulosa Cell Dysfunction and Impaired Ovarian Response
Sri Ramya Donepudi, University of Pittsburgh
Investigating The Role Of Epoxyeicosatrienoic Acids In Allergic Asthma: Sex Differences And The Effect Of Seh Inhibitor On Lung Function In Females And Males
Investigating The Role Of Epoxyeicosatrienoic Acids In Allergic Asthma: Sex Differences And The Effect Of Seh Inhibitor On Lung Function In Females And Males
Ke Shan, Duke Univeristy
TMEM16F as a Regulator of Ferroptosis in Astrocytes and Trophoblasts: Implications for Neurodegeneration and Placental Biology
TMEM16F as a Regulator of Ferroptosis in Astrocytes and Trophoblasts: Implications for Neurodegeneration and Placental Biology
Coffee Available
4:30–5:00 PM
Colorado Ballroom Foyer
Phospholipid Metabolism in Physiology and Disease
5:00–7:00 PM
Peaks 4 - 5
Vytas A. Bankaitis, Texas A&M University
Phosphatidylinositol Transfer Protein Function and Disease in Mammals
Phosphatidylinositol Transfer Protein Function and Disease in Mammals
Timothy T Hla, Boston Children's Hospital/Harvard Medical School
Endothelial Protective Property of S1P as a Therapeutic Strategy in Diseases of Multiple Organ Systems
Endothelial Protective Property of S1P as a Therapeutic Strategy in Diseases of Multiple Organ Systems
Junken Aoki, University of Tokyo
An Emerging Role of PAQR Family Members as Phospholipid Remodeling PLA2
An Emerging Role of PAQR Family Members as Phospholipid Remodeling PLA2
William L. Holland, University of Utah
Genetics of Hyperceramidemia
Genetics of Hyperceramidemia
Social Hour with Lite Bites
7:00–8:00 PM
Peaks 1 - 3
Poster Session 2
7:30–10:00 PM
Peaks 1 - 3
Wednesday, April 9, 2025
Breakfast
7:00–8:00 AM
Summit Gallery
Lipids and Regulation of Cellular Homeostasis
8:00–11:00 AM
Peaks 4 - 5
Takeshi Harayama, Institute of Molecular and Cellular Pharmacology
Manipulating Cellular Lipidome to Discover Novel Regulatory Mechanisms of Lipid Composition
Manipulating Cellular Lipidome to Discover Novel Regulatory Mechanisms of Lipid Composition
Meng C. Wang, HHMI/Janelia Research Campus
Lysosome Lipid Signaling in Neurons Regulates Longevity
Lysosome Lipid Signaling in Neurons Regulates Longevity
Stacy L Gelhaus, University of Pittsburgh
Electrophilic Fatty Acid Regulation of Cellular Metabolism Mediates Inflammation Resolution
Electrophilic Fatty Acid Regulation of Cellular Metabolism Mediates Inflammation Resolution
Kasparas Petkevicius, University of Cambridge
CLN8 is an acyltransferase catalyzing a key step in bis(monoacylglycero)phosphate biosynthesis
CLN8 is an acyltransferase catalyzing a key step in bis(monoacylglycero)phosphate biosynthesis
Maia Kinnebrew, Stanford University
Short Talk: ACC1 Controls Plasma Membrane Accessible Cholesterol Homeostasis By Regulating Lipid Droplet Abundance
Short Talk: ACC1 Controls Plasma Membrane Accessible Cholesterol Homeostasis By Regulating Lipid Droplet Abundance
Johannes Morstein, UCSF
Short Talk: Direct Targeting of Protein-Membrane Interactions
Short Talk: Direct Targeting of Protein-Membrane Interactions
Gregory Wyant, MGH/HMS
Short Talk: Plasmalogen Control of Peroxisome Degradation Confers Ischemic Protection
Short Talk: Plasmalogen Control of Peroxisome Degradation Confers Ischemic Protection
Coffee Break
9:00–9:20 AM
Colorado Ballroom Foyer
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight: Research Presentations Selected from Abstract Submissions
2:30–4:30 PM
Peaks 4 - 5
Alan R Brash, Vanderbilt University School of Medicine
Structural Basis Of Covalent Binding Of Acylceramides In Formation Of The Skin Permeability Barrier
Structural Basis Of Covalent Binding Of Acylceramides In Formation Of The Skin Permeability Barrier
Alessandra Ferrari, University of California, Berkeley
Nonvesicular Trafficking In Enterocytes Facilitates The Uptake Of Diet-Derived Cholesterol
Nonvesicular Trafficking In Enterocytes Facilitates The Uptake Of Diet-Derived Cholesterol
Anna Hains, University of Manchester
Ceramides Mediate the Resolution of Psoriasis-Like Skin Inflammation
Ceramides Mediate the Resolution of Psoriasis-Like Skin Inflammation
Takese T McKenzie, MD Anderson Cancer Center
Loss Of Lipocalin Prostaglandin D2 Synthase Impairs Myelin Debris Clearance And Microglial Activation During Demyelination
Loss Of Lipocalin Prostaglandin D2 Synthase Impairs Myelin Debris Clearance And Microglial Activation During Demyelination
Ginger L. Milne, Vanderbilt University Medical Center
Metabolism Of Oxidized Lipid Mediators By UDP-Glucuronosyltransferases (Ugts): Implications For In Vivo Quantification
Metabolism Of Oxidized Lipid Mediators By UDP-Glucuronosyltransferases (Ugts): Implications For In Vivo Quantification
Brendan Prideaux, University of Texas Medical Branch
Brendan Prideau
Brendan Prideau
Bin Zheng, Cedars-Sinai Medical Center
DHODH Modulates Immune Evasion of Cancer Cells Via CDP-Choline Dependent Regulation of Phospholipid Metabolism
DHODH Modulates Immune Evasion of Cancer Cells Via CDP-Choline Dependent Regulation of Phospholipid Metabolism
Coffee Available
4:30–5:00 PM
Colorado Ballroom Foyer
Bioactive Lipids in Inflammatory Disease
5:00–6:45 PM
Peaks 4 - 5
Valerie B. O'Donnell, Cardiff University
The SARS-CoV2 Envelope Responds to Host Lipid Metabolism through Changing its Coat
The SARS-CoV2 Envelope Responds to Host Lipid Metabolism through Changing its Coat
Scott A. Summers, University of Utah
Remodeling the Ceramide Backbone to Treat Cardiorenal Metabolic Disease
Remodeling the Ceramide Backbone to Treat Cardiorenal Metabolic Disease
Mei Yee Koh, University of Utah
Short Talk: HAF Promotes Lipid Dysregulation and Progression from MASH to MASH-HCC
Short Talk: HAF Promotes Lipid Dysregulation and Progression from MASH to MASH-HCC
Marta Overchuk, University of North Carolina at Chapel Hill
Short Talk: Concurrent Induction of Ferroptosis- and Apoptosis-like Lipid Signatures in Ovarian Cancer Cells with Photodynamic Therapy
Short Talk: Concurrent Induction of Ferroptosis- and Apoptosis-like Lipid Signatures in Ovarian Cancer Cells with Photodynamic Therapy
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Peaks 4 - 5
Social Hour with Lite Bites
7:00–8:00 PM
Peaks 1 - 3
Entertainment
8:00–9:00 PM
Peaks 4 - 5
Cash Bar
8:00–9:00 PM
Peaks 1 - 3
Thursday, April 10, 2025
Departure
12:00–11:59 PM
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