Tumor Metabolism: Environmental Influences and Therapeutic Vulnerabilities
March 16-19, 2025 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Shannon Mumenthaler, Kathryn E. Wellen and Arkaitz Carracedo
In Person
On Demand
March 16-19, 2025 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Shannon Mumenthaler, Kathryn E. Wellen and Arkaitz Carracedo
Available Formats:
In Person
On Demand
Supported by the Directors' Fund
Available Formats: = In Person = On Demand
Sunday, March 16, 2025
Booking Function
Fundraising
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Monday, March 17, 2025
Breakfast
7:00–8:00 AM
Welcome and Keynote Session
8:00–9:00 AM
Joshua D. Rabinowitz, Princeton University
Metabolic Flux Analysis in Cancer
Metabolic Flux Analysis in Cancer
Tomi Akinyemiju, Duke University
Health Disparities/Equity in Research or the Clinic as it Applies to Tumor Metabolism
Health Disparities/Equity in Research or the Clinic as it Applies to Tumor Metabolism
Therapeutic Targeting of Metabolism
9:00–11:00 AM
Issam Ben-Sahra, Northwestern University
Regulation of Nucleotide Metabolism in Cancer Cells
Regulation of Nucleotide Metabolism in Cancer Cells
Marianne Koritzinsky, University of Toronto
Cellular Metabolism and Radiotherapy
Cellular Metabolism and Radiotherapy
Jonathan D. Powell, Calico Life Sciences
Glutamine Antagonism and Immunotherapy
Glutamine Antagonism and Immunotherapy
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
On Own for Lunch
11:15–5:00 PM
Poster Setup
11:15–1:00 PM
Poster Viewing
1:00–10:00 PM
Workshop 1: New Strategies for Therapeutic Targeting of Metabolism
1:30–3:15 PM
Short Talk(s) Chosen from Abstracts
Panel Discussion 1: Diversity and Equity in Research and Clinical Approaches
3:30–4:30 PM
Coffee Available
4:30–5:00 PM
Signaling, Epigenetics and Tumor Metabolism
5:00–7:00 PM
Arkaitz Carracedo, Center for Cooperative Research in Biosciences
Cancer Metabolism and Cell Signaling
Cancer Metabolism and Cell Signaling
Speaker to be Announced
Sara Sdelci, Centre for Genomic Regulation
Epigenetic Face of Cancer Metabolism
Epigenetic Face of Cancer Metabolism
Kathryn E. Wellen, University of Pennsylvania
Acetyl-CoA at the Crossroads of Metabolism and Gene Expression
Acetyl-CoA at the Crossroads of Metabolism and Gene Expression
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Tuesday, March 18, 2025
Breakfast
7:00–8:00 AM
Metabolic Crosstalk Between Tumor Cells and their Microenvironment
8:00–11:00 AM
Shannon Mumenthaler, University of Southern California
Biomimetic Models to Study Tumor Metabolism in Context
Biomimetic Models to Study Tumor Metabolism in Context
M. Celeste Simon, University of Pennsylvania
Effects of Hypoxia on Cancer Metabolism
Effects of Hypoxia on Cancer Metabolism
Sara Zanivan, CRUK Scotland Institute
CAF Metabolism and the Immune Tumor Microenvironment
CAF Metabolism and the Immune Tumor Microenvironment
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Poster Setup
11:00–1:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Immune Microenvironment and Metabolism
5:00–7:00 PM
Costas A. Lyssiotis, University of Michigan
Metabolic Networks in the Immune Microenvironment
Metabolic Networks in the Immune Microenvironment
Stacey D. Finley, University of Southern California
Systems Biology Modeling of Metabolic Interactions in the Tumor Microenvironment
Systems Biology Modeling of Metabolic Interactions in the Tumor Microenvironment
Lydia Lynch, Princeton University
Immunometabolism in Obesity and Cancer
Immunometabolism in Obesity and Cancer
Short Talk(s) Chosen from Abstracts
Social Hour with Lite Bites
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, March 19, 2025
Breakfast
7:00–8:00 AM
Systemic Influences on Tumor Metabolism
8:00–11:00 AM
Matthew G. Vander Heiden, Massachusetts Institute of Technology
Diet and Tumor Metabolism
Diet and Tumor Metabolism
Sarah-Maria Fendt, VIB-KU Leuven
Metabolic Vulnerabilities of Metastatic Cancer Cells
Metabolic Vulnerabilities of Metastatic Cancer Cells
Marcus D. Goncalves, Weill Cornell Medicine
Cancer Cachexia
Cancer Cachexia
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Workshop 2: Understanding how Environment (Local and Systemic) Impacts Tumorigenesis
1:30–3:15 PM
Short Talk(s) Chosen from Abstracts
Panel Discussion 2: Innovative Clinical Trial Strategies
3:30–4:30 PM
Coffee Available
4:30–5:00 PM
Challenges in Targeting Cancer Metabolism: Lessons Learned
5:00–6:45 PM
Chi Van Dang, Ludwig Institute for Cancer Research
MYC and The Complexity of Targeting Cell Metabolism
MYC and The Complexity of Targeting Cell Metabolism
Andrew M. Intlekofer, Memorial Sloan Kettering Cancer Center
Acquired resistance to IDH inhibition
Acquired resistance to IDH inhibition
Ayelet Erez, Weizmann Institute of Science
Nucleotide Imbalance and Immunotherapy
Nucleotide Imbalance and Immunotherapy
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Lite Bites
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Thursday, March 20, 2025
Departure
12:00–11:59 PM
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