Immunometabolism across Scales: From Cells to Systems to Healthspan' focuses on the intersection between immunology and metabolism that contribute to longevity to pioneer advancements in health and disease treatment. This meeting aims to highlight the critical yet underexplored intersectionality of metabolic and immune processes at all biological levels. The sessions will address the intricacies of nutrient signaling, the immune system's adaptive mechanisms across varied metabolic ecosystems, and the pivotal role of microbial metabolites in modulation of nutrition and immunity. Further, we tackle neuro-immune interactions and their crucial functions in health, alongside the overarching control mechanisms governing aging and systemic metabolism. The conference's objectives are to: 1) Illuminate the uncharted territories of immunometabolism from cellular mechanisms to system-wide impacts; 2) Foster multidisciplinary collaborations that bridge current investigative silos; 3) Equip the next generation of scientists with the knowledge and tools necessary for innovation in this evolving field; and 4) Identify actionable strategies to translate research findings into clinical interventions aimed at enhancing healthspan. Anticipated outcomes include the dissemination of groundbreaking scientific knowledge, the development of novel methodologies, and the establishment of robust collaborative networks. Attendees will leave with enriched perspectives, ready to implement advanced techniques and new approaches to their own research. Upon conclusion of this meeting the field of immunometabolism will be poised to shift towards a more integrated approach to leveraging immunity and metabolism to ultimately pave the way for novel intervention to increase healthspan.