This meeting took place in 2019



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Epigenetics and Human Disease (X5)


Organizer(s) Cheryl H. Arrowsmith, Anne Schaefer and Mark A. Dawson
March 17—21, 2019
Fairmont Banff Springs • Banff, Alberta Canada
Discounted Abstract Deadline: Nov 29, 2018
Abstract Deadline: Dec 12, 2018
Scholarship Deadline: Nov 29, 2018
Discounted Registration Deadline: Jan 22, 2019

Sponsored by Cell Research, Incyte Corporation, Novartis Institutes for BioMedical Research and Pfizer Inc.


Summary of Meeting:
Epigenetics is a major mechanism in human health and disease. Data from a range of diseases (cancer, neurological and immunological disorders) have uncovered altered epigenomes arising from mutations, altered expression and/or copy number alterations of numerous epigenetic factors (histones, DNA and chromatin modifying enzymes, reader proteins, chromatin modulators and noncoding RNAs). Genome-wide analyses have illustrated the relationship between altered epigenetic states (e.g., modified DNA, histones and chromatin packaging) and disease onset and progression. Furthermore, both local and long-range nuclear chromatin architecture are increasingly recognized as major contributors to normal and pathologic epigenetic states. This conference, held jointly with a conference on “3D Genome”, will cover the most current knowledge of epigenetic events modulating nuclear function (gene expression regulation, enhancer modulation, domains and structural organization as well as cell division and differentiation), while relating this to normal and disease models. In addition, this conference will highlight the impact that preclinical and clinical epigenetic therapeutics have on multiple diseases including cancer, immunological and neurological disorders. An interdisciplinary panel of speakers including both thought leaders in the field as well as young investigators will survey the latest research results and conceptual understanding of fundamental mechanisms of epigenetic signaling, especially as they relate to regulation of gene expression programs. Presentations and workshops will highlight the latest technologies and methodologies for studying epigenetic states and 3D chromatin architecture in cells, tissues and organisms.

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Scholarships/Awards

Keystone Symposia Future of Science Fund Scholarship Recipients

Carol Chen
Research Institute of McGill University Health Centre, Canada

M. Ryan Corces
Stanford University, USA

Jan Czerminski
University of Massachusetts Medical School, USA

Lorna Farrelly
Icahn School of Medicine at Mount Sinai, USA

Jonathan Enrique Sandoval
University of California, Santa Barbara, USA

Rohan Nishant Shah
University of Chicago, USA

Monika Steininger
Research Institute of Molecular Pathology, Austria

Qiao Su
Carnegie Mellon University, USA

National Cancer Institute (NCI) Scholarship Recipients

Christopher Cali
University of Pennsylvania, USA

Calvin S. Leung
University of California, Los Angeles, USA

Josefa M. Sullivan
Icahn School of Medicine at Mount Sinai, USA

Sachi Nakashima Memorial Fellowship Scholarship Scholarship Recipients

Omer Gilan
Peter MacCallum Cancer Centre, Australia