Fairmont Banff Springs Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Tuberculosis: Mechanisms, Pathogenesis and Treatment (A3)

Scientific Organizers: Christina L. Stallings, Veronique Anne Dartois, Stewart T. Cole and David Barros


January 17—21, 2019

Fairmont Banff Springs, Banff, Alberta, Canada


Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

Sponsored by Merck & Co., Inc.


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for oral short talks. Abstracts for poster display opportunities will be accepted until 6 weeks before meeting start date midnight MST.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Global Health Travel Award Deadline: Aug 14, 2018 [details]
Scholarship Deadline: Oct 11, 2018 [details]
Discounted Abstract Deadline: Oct 11, 2018 [details]
Abstract Deadline: Oct 23, 2018 [details]
Discounted Registration Deadline: Nov 20, 2018 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2019-A3 "Tuberculosis: Mechanisms, Pathogenesis and Treatment" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On October 11, 2018 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After October 11, 2018 until December 6, 2018 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
October 11, 2018 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 20, 2018 945.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After November 20, 2018 1145.00 USD
Discounted STUDENT Registration
More details
Before and On November 20, 2018 720.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After November 20, 2018 920.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: October 11, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 23, 2018)

Global Health Travel Award Deadline: August 14, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: October 11, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 23, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is October 11, 2018)

Discounted Registration Deadline: November 20, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 945.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1145.00 USD*
Student Registration Fee: 920.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Thursday, January 17 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Monday, January 21 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Tuesday, January 22 in order to fully experience the meeting.

THURSDAY, JANUARY 17

16:00—20:00
Arrival and Registration

Van Horne Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Van Horne Foyer

FRIDAY, JANUARY 18

07:00—08:00
Breakfast

08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Wim Parys, Janssen Research Foundation, Belgium
Developing Drugs Against Global Health Threats

09:00—11:45
Pathogenic Strategies of Mycobacteria
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Scarlet S. Shell, Worcester Polytechnic Institute, USA
The Intersection of Stress Response and RNA Metabolism in mycobacteria

Coffee Break

Dirk Schnappinger, Weill Cornell Medical College, USA
Determinants of Growth, Persistence and Relapse

Jeremy Rock, Rockefeller University, USA
Genetic Dissection of Pathogenesis

Samuel H. Becker†, New York University School of Medicine, USA
Short Talk: The Mycobacterium Tuberculosis Proteasome Regulates Nitrate Metabolism Through an Essential Protein Quality Control System

Miriam Braunstein†, University of North Carolina at Chapel Hill, USA
Short Talk: Mycobacterium tuberculosis SatS (Rv3311) is a Chaperone for the SecA2 Protein Export Pathway

Damian C. Ekiert†, University of Chicago, USA
Short Talk: MCE Protein Architectures Suggest Mechanisms of Transport Across the Envelope

11:45—17:00
On Own for Lunch

11:45—13:00
Poster Setup

Van Horne B/C
13:00—22:00
Poster Viewing

Van Horne B/C
14:30—16:30
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis Mycobacteria

Van Horne A
Tucker J. Piergallini†, Texas Biomedical Research Institute, USA
Systemically-Increased Inflammation Causes Enhanced Early Control of Mycobacterium tuberculosis Infection in Young Mice via an Early Hyper-Inflammatory Immune Response, Mimicking M.tb Infection in Aged Mice

Anna Kathleen Coussens†, Walter and Eliza Hall Institute, Australia
Seasonal Immunity in TB-HIV Pathogenesis

Avuyonke Balfour†, University of Cape Town, South Africa
The Effect of Tuberculosis (TB) and HIV-TB on Mucosal-Associated Invariant T (MAIT) Cells in Humans

Brendan K. Podell†, Colorado State University, USA
Early Immune Events Dictating Outcome in Diabetes-Tuberculosis Comorbidity

Ananya Nandy†, CSIR-Institute of Genomics and Integrative Biology, India
Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Oxidative Stress Mitigation Property of Bacilli in Lipid Rich Caseous Environment

Julia Marianna Scordo†, Texas Biomedical Research Institute, USA
Human Alveolar Lining Fluid Drives Mycobacterium tuberculosis Infection Outcome in Alveolar Epithelial Cells

Jaryd Sullivan†, McGill University Health Centre, Canada
A Novel Screening Platform for Non-Tuberculous Mycobacteria Drug Discovery

Daniel Barkan†, Hebrew University, Israel
The Virulence-Essential Secretion System ESX-4 in Mycobacterium abscessus is Regulated by A Small Non-Coding RNA

16:30—17:00
Coffee Available

17:00—19:00
Immune Responses to Mycobacterium Tuberculosis
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Christina L. Stallings, Washington University School of Medicine, USA
Innate Immune Responses to Mycobacterium Tuberculosis

Katrin D. Mayer-Barber, NIAID, National Institutes of Health, USA
Cellular Dynamics of Innate Effector Cells during Mtb Infection

Galit Alter, Ragon Institute of MGH, MIT and Harvard, USA
Antibodies and TB

Jason D. Simmons†, University of Washington, USA
Short Talk: Resistance to Latent Mycobacterium Tuberculosis Infection is Associated with Distinct Monocyte Transcriptional Programs

Micah Dunlap†, Washington University School of Medicine in St. Louis, USA
Short Talk: A Novel Role for C-C Motif Chemokine Receptor 2 During Infection with Hypervirulent Mycobacterium Tuberculosis

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Van Horne B/C
19:30—22:00
Poster Session 1

Van Horne B/C

SATURDAY, JANUARY 19

07:00—08:00
Breakfast

08:00—11:30
Host Cell Signaling and Invasion
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Jeffery S. Cox, University of California, Berkeley, USA
Using Global Proteomics to Discover New Anti-TB Pathways of Macrophages

Ulrich E. Schaible, Research Center Borstel, Germany
Pathogen - Host Cell Interactions in Tuberculosis

Coffee Break

Jyothi Rengarajan, Emory University School of Medicine, USA
Modulation of Host Responses

Michael Shiloh, University of Texas Southwestern Medical Center, USA
Invasion of the Mucosa by Mycobacterium Tuberculosis

Francisco J. Roca Soler†, University of Cambridge, UK
Short Talk: TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis Through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit

Amy K. Barczak†, Massachusetts General Hospital, USA
Short Talk: Lipid Bodies Link Macrophage ER Stress with Innate Immune Recognition of Mtb Infection

Julius H. Brandenburg†, Research Center Borstel, Germany
Short Talk: Mycobacterium Tuberculosis Exploits WNT6-Induced Acetyl-CoA Carboxylase-2 Driven Perturbation of Host Lipid Homeostasis to Promote Growth in Macrophages

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Van Horne B/C
13:00—22:00
Poster Viewing

Van Horne B/C
14:30—16:30
Workshop 2: TB Drug Targets and MOA

Van Horne A
Anthony David Baughn†, University of Minnesota, USA
Conditional Susceptibility to Pyrazinamide is Driven by a Specific Stress Response in Mycobacterium Tuberculosis

Jyothi Padiadpu†, Center for Infectious Disease Research, USA
Kinome Deconvolution to Delineate Host Regulators and Inhibitors of Tuberculosis Infection

Gareth Adrian Prosser†, National Institutes of Health, USA
Unraveling the Physiological Roles of the M. Tuberculosis PrrAB Two-Component System

Nancy Woychik†, Rutgers University, USA
Selective Toxin-Mediated Ribosome Stalling Surgically Reprograms the Mycobacterium Tuberculosis Proteome

Eachan Oliver Johnson†, Broad Institute, USA
Large-Scale Chemical-Genetic Interaction Profiling Yields New Classes of Inhibitors of Mycobacterium tuberculosis

Kaley M. Wilburn†, Cornell University, USA
Inducing cAMP Production in Mycobacterium tuberculosis is Sufficient to Stall Cholesterol Utilization

Anil Kumar Ojha†, Wadsworth Center/University at Albany, USA
Zincxing Mycobacterial Ribosomes: Targeting Regulation of Ribosome Hibernation to Increase Antibiotic Efficacies

Fredrik Almqvist†, Umeå University, Sweden
Design, Synthesis and Evaluation of Novel ∆2- Thiazolino 2-Pyridone Derivatives as Mycobacterium Tuberculosis Tolerance Inhibitors

16:30—17:00
Coffee Available

17:00—19:00
Translation of New Therapeutic, Diagnostic, and Vaccination Strategies
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Ranjan Kumar Nanda, International Center for Genetic Engineering and Biotechnology, India
Brain-Gut-Microbiota Axis in Tuberculosis

Jennifer Gardiner, Bill & Melinda Gates Foundation, USA
Biomarkers of Infection, Disease and Response to Therapy

Nicholas Paton, National University of Singapore, Singapore
New Approaches to Testing TB Regimens in Clinical Trials

Phillip A. Swanson II†, NIH, USA
Short Talk: T Cell Immunity in the Blood Following Aerosol, Intravenous, or Intradermal Administration of BCG in Nonhuman Primates

Brian D. Robertson†, Imperial College London, UK
Short Talk: Development of a Human Challenge Model for Tuberculosis

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Van Horne B/C
19:30—22:00
Poster Session 2

Van Horne B/C

SUNDAY, JANUARY 20

07:00—08:00
Breakfast

08:00—11:30
Treatment and Diagnosis of Disease
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
David B. Olsen, Merck & Co., Inc., USA
New Oxazolidinones against TB

Claudia Denkinger, FIND, Switzerland
Updates on the TB Diagnostic Pipeline to Find the 'Missing Millions' and Inform Therapy

Coffee Break

Rada Savic, University of California, San Francisco, USA
Talk Title to be Announced

Louis J. Picker, Oregon Health & Science University, USA
Development of Cytomegalovirus-based Vectors for a Tuberculosis Vaccine

Jan Rybniker†, University Clinic Cologne, Germany
Short Talk: Corticosteroids Potently Abrogate p38 MAPK Dependent Necrotic Cell Death Induced by Mycobacterium Tuberculosis - Implications for Host-Directed Therapies

Sadhana Chauhan†, University of Texas Medical Branch, USA
Short Talk: Role of Arginine Metabolism Disruption in the Pathogenesis of TB and HIV Co-Infection

Catherine Ong†, National University of Singapore, Singapore
Short Talk: MMP Inhibition Using Doxycycline with Standard Anti-Tuberculous Treatment in TB Patients: A Phase II Randomized-Controlled Trial

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Van Horne B/C
13:00—22:00
Poster Viewing

Van Horne B/C
16:30—17:00
Coffee Available

17:00—19:00
Molecular Dissection and Targeting of Mycobacterium Tuberculosis
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Robert B. Abramovitch, Michigan State University, USA
Targeting Two-Component Regulatory Systems to Inhibit Mycobacterium tuberculosis Pathogenesis

Digby F. Warner, University of Cape Town, South Africa
New Tools for Target Validation and Mechanism of Action Studies

Stewart T. Cole, Institut Pasteur, France
Drug Discovery through Genetics

Yasu S. Morita†, University of Massachusetts, USA
Short Talk: Functional Compartmentalization of Plasma Membrane in Mycobacterium Tuberculosis

Chiara Toniolo†, Swiss Federal Institute of Technology in Lausanne, Switzerland
Short Talk: Cell-to-Cell Phenotypic Heterogeneity in the Interactions Between Macrophages and Mycobacterium tuberculosis

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Van Horne B/C
19:30—22:00
Poster Session 3

Van Horne B/C

MONDAY, JANUARY 21

07:00—08:00
Breakfast

08:00—11:30
Mycobacterial and Host Vulnerabilities
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
David Barros, GlaxoSmithKline, Spain
Drug Discovery and Development in TB

Thomas Dick, New Jersey Medical School - Rutgers, The State University of New Jersey, USA
Mechanism of Action of PZA

Coffee Break

Mary Jackson, Colorado State University, USA
Therapeutic potential of the FAS-II dehydratases of Mycobacterium tuberculosis

Adrie J. C. Steyn, Africa Health Research Institute & UAB, South Africa
The Human Tuberculous Lung: An Untapped Resource to Generate a High-Resolution 3D Lung Atlas

Andrej Trauner†, Swiss Tropical and Public Health Institute, Switzerland
Short Talk: Resource Misallocation as A Mediator of Fitness Costs in Rifampicin Resistance

Rujapak Sutiwisesak†, University of Massachusetts Medical School, USA
Short Talk: Natural Polymorphisms in the esxH Gene of Mycobacterium Tuberculosis Affect T Cell Immunity Following Infection

Daisy Xiaoxi Ji†, University of California, Berkeley, USA
Short Talk: Genetic Control of the Susceptibility to M. Tuberculosis Infection by the Sst1S Locus

11:30—17:00
On Own for Lunch

14:30—16:30
Panel: Careers in Biomedical Research

Van Horne A
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—18:45
Host Determinants of Disease Outcomes
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
Michael Stephen Glickman, Memorial Sloan-Kettering Institute, USA
The Microbiome and TB

Philana Ling Lin, University of Pittsburgh, USA
Nonhuman Primate Models of TB

Christopher M. Sassetti, University of Massachusetts Medical School, USA
Host and Bacterial Determinants of TB Outcome

Benjamin Henry Gern†, Seattle Children's, USA
Short Talk: TGFβ Restricts T Cell IFN©production in Pulmonary Tuberculous Granulomas

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/17/2018

Van Horne A
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Van Horne B/C
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Van Horne B/C

TUESDAY, JANUARY 22

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bill & Melinda Gates Foundation Merck & Co., Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676