Snowbird Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

DNA Replication and Genome Instability: From Mechanism to Disease (A1)

Scientific Organizers: Karlene A. Cimprich, Mark J. O'Connor and Johannes C. Walter


January 13—17, 2019

Snowbird Resort, Snowbird, Utah, USA


Organized in collaboration with Cancer Research UK

Supported by the Directors' Fund


BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Sep 20, 2018 [details]
Discounted Abstract Deadline: Sep 20, 2018 [details]
Abstract Deadline: Oct 16, 2018 [details]
Discounted Registration Deadline: Nov 13, 2018 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2019-A1 "DNA Replication and Genome Instability: From Mechanism to Disease" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 20, 2018 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 20, 2018 until October 16, 2018 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 20, 2018 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 13, 2018 845.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After November 13, 2018 1045.00 USD
Discounted STUDENT Registration
More details
Before and On November 13, 2018 620.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After November 13, 2018 820.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.

Apply for a Scholarship



Discounted Abstract Deadline: September 20, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 16, 2018)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: September 20, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 16, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is September 20, 2018)

Discounted Registration Deadline: November 13, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 845.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 620.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1045.00 USD*
Student Registration Fee: 820.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 13 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 17 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 18 in order to fully experience the meeting.

SUNDAY, JANUARY 13

16:00—20:00
Arrival and Registration

18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.


MONDAY, JANUARY 14

07:00—08:00
Breakfast

08:00—09:30
Welcome and Keynote Session
Registered attendees can view abstracts starting on 12/13/2018

David Cortez, Vanderbilt University School of Medicine, USA
New Players in Modulating Replication Fork Stability

Eric C. Greene, Columbia University, USA
Single Molecule Analysis of Recombination

Coffee Break

09:50—11:15
The Influence of Chromatin on Replication and Repair
Registered attendees can view abstracts starting on 12/13/2018

Iestyn Whitehouse, Memorial Sloan Kettering Cancer Center, USA
Interplay of Chromatin and Replication

Gaelle Legube, Center for Integrative Biology, France
Effect of Chromatin Structure on Recombination/Repair

Short Talk(s) Chosen from Abstracts

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

13:00—22:00
Poster Viewing

14:30—16:30
Workshop 1: Basic Mechanisms of Replication

* Antoine M. van Oijen, University of Wollongong, Australia
Single Molecule Studies of Replication

Short Talks Chosen from Abstracts

14:30—16:30
Workshop 2: Basic Mechanisms of Recombination

* Wolf-Dietrich Heyer, University of California, Davis, USA
Mechanisms of Recombination

Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—19:00
Mechanisms of DNA Replication
Registered attendees can view abstracts starting on 12/13/2018

John F.X. Diffley, Francis Crick Institute, UK
Mechanisms of DNA Replication Initiation and Progression

Karim Labib, University of Dundee, UK
Mechanism of DNA Replication Termination and Replisome Disassembly

Speaker to be Announced

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

19:30—22:00
Poster Session 1


TUESDAY, JANUARY 15

07:00—08:00
Breakfast

08:00—11:00
Mechanisms of Recombination and Repair
Registered attendees can view abstracts starting on 12/13/2018

Stephen C. West, Francis Crick Institute, UK
Mechanisms of Replication/Recombination Intermediate Resolution

Anna Malkova, University of Iowa, USA
Mechanism of Break-Induced Replication

Coffee Break

Agnel Sfeir, New York University School of Medicine, USA
Mechanism of Alternative End-Joining

Daniel Durocher, Lunenfeld-Tanenbaum Research Institute, Canada
Cell Cycle Regulation of Double-Strand Break Repair

Short Talk(s) Chosen from Abstracts

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

13:00—22:00
Poster Viewing

16:30—17:00
Coffee Available

17:00—19:00
Understanding and Exploiting Replication Stress
Registered attendees can view abstracts starting on 12/13/2018

Sarah AE Lambert, Institute Curie, France
Spatial Organization of Replication Fork Processing

Massimo Lopes, University of Z├╝rich, Switzerland
Replication Fork Remodeling upon Cancer-relevant Replication Stress

Mark J. O'Connor, AstraZeneca, UK
Targeting Replication Stress in Cancer

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

19:30—22:00
Poster Session 2


WEDNESDAY, JANUARY 16

07:00—08:00
Breakfast

08:00—11:00
Overcoming Replication Fork Obstacles
Registered attendees can view abstracts starting on 12/13/2018

Johannes C. Walter, Harvard Medical School, USA
Mechanisms of Cross-Link Repair

Ralph Scully, Beth Israel Deaconess Medical Center, USA
Recombination and Repair at Stalled Mammalian Replication Forks

Coffee Break

Dana Branzei, FIRC Institute of Molecular Oncology, Italy
Rewiring of DNA Damage Tolerance at the Replication Fork

Ketan J. Patel, MRC Laboratory of Molecular Biology, UK
Endogenous Sources of Inter-Strand Crosslinks and Fanconi Anemia

Short Talk(s) Chosen from Abstracts

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

13:00—22:00
Poster Viewing

14:30—16:30
Workshop/Panel Discussion 3: Translating Basic Science to the Clinic

* Mark J. O'Connor, AstraZeneca, UK

* Daniel Durocher, Lunenfeld-Tanenbaum Research Institute, Canada

Yves G. Pommier, NCI, National Institutes of Health, USA

Alan D. D'Andrea, Dana-Farber Cancer Institute, USA

Lauren A. Byers, University of Texas MD Anderson Cancer Center, USA
Targeting DNA Damage Response (DDR) in Lung Cancer

16:30—17:00
Coffee Available

17:00—19:00
RNA-Induced Genome Instability
Registered attendees can view abstracts starting on 12/13/2018

Karlene A. Cimprich, Stanford University, USA
R-Loops and Transcription-Replication Collisions

Speaker to be Announced

Speaker to be Announced

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

19:30—22:00
Poster Session 3


THURSDAY, JANUARY 17

07:00—08:00
Breakfast

08:00—11:00
Genomic Drivers of Tumorignesis and Drug Resistance
Registered attendees can view abstracts starting on 12/13/2018

Titia de Lange, Rockefeller University, USA
Telomeres and the DNA Damage Response

Serena Nik-Zainal, University of Cambridge, UK
Mutational Signatures associated with Replication and Genome Instability

Coffee Break

Christopher Lord, Institute of Cancer Research, UK
Using Genetics to Understand Synthetic Lethal Sensitivity and Resistance to DDR Inhibitors

Stephen P. Jackson, University of Cambridge, UK
Resistance to Molecularly-Targeted Anti-Cancer Therapeutics

Short Talk(s) Chosen from Abstracts

11:00—17:00
On Own for Lunch

14:30—16:30
Workshop 4: Chromatin, Replication and Repair

* Evi Soutoglou, Institute of Genetics and Molecular and Cellular Biology, France
Double Strand Break Repair in Heterochromatin

Short Talks Chosen from Abstracts

14:30—16:30
Workshop 5: Replication Stress and DNA Damage Signaling

* Niels Mailand, University of Copenhagen, Denmark
Ubiquitin- and SUMO-Mediated Responses to Replication Stress

Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—18:45
Linking DNA Damage Response to the Immune Response
Registered attendees can view abstracts starting on 12/13/2018

Roger A. Greenberg, University of Pennsylvania Perelman School of Medicine, USA
DNA Damage Response Kinases and the Immune Response

Alberto Bardelli, University of Torino, Italy
Inactivation of DNA Repair to Improve Immune Surveillance

Sophie Postel-Vinay, Gustave Roussy Cancer Campus, France
The Next Step-Change in Cancer Therapy? Combining DDR Inhibitors with Immunotherapy

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/13/2018

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.


FRIDAY, JANUARY 18

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge additional support for this conference from:

Organized in collaboration with Cancer Research UK

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676