Fairmont Copley Plaza Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2017



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Engineered Cells and Tissues as Platforms for Discovery and Therapy (K1)


Organizer(s) Laura E. Niklason, Milica Radisic and Nenad Bursac
March 9—12, 2017
Fairmont Copley Plaza • Boston, Massachusetts USA
Discounted Abstract Deadline: Nov 9, 2016
Abstract Deadline: Dec 13, 2016
Scholarship Deadline: Nov 9, 2016
Discounted Registration Deadline: Jan 13, 2017

Sponsored by Editas Medicine, Inc., Juno Therapeutics, Merck & Co., Inc. and Thermo Fisher Scientific Inc.

Summary of Meeting:
Tissue engineering, cell therapies and regenerative medicine have witnessed accelerated progress over the past decade. Fueled by fundamental discoveries in iPS, progenitor, and developmental cell biology, cells are now used as building blocks to create model systems, as testing platforms for drug interventions and as active therapeutics. High-throughput production of various types of “microtissues” or “organoids” is making increasing contributions to our understanding of human development, disease and repair. This Keystone Symposia meeting will highlight these rapidly emerging cell-based tools for fundamental and applied discovery. Culture systems ranging from simple cell cluster organoids, to highly advanced cell-electronic composites, will be discussed. In addition, the encouraging progress that is being made in cell-based therapies across a range of organs and diseases will be featured. The goal of this meeting is to provide a state-of-the-art review of both pluripotent and differentiated cells as tools for discovery and therapy. A broad range of cell types and therapeutic areas will be included.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Thursday, March 9 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Sunday, March 12 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Monday, March 13 in order to fully experience the meeting.

THURSDAY, MARCH 9

16:00—20:00
Arrival and Registration

Lobby
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Venetian Room

FRIDAY, MARCH 10

07:30—08:30
Breakfast

Venetian Room
08:30—09:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Laura E. Niklason, Yale University, USA

Danilo Tagle, NCATS, National Institutes of Health, USA
Catalyzing Translational Innovation

09:30—12:15
Biologically-Based Microsystems
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Jordan S. Miller, Rice University, USA

Jeffrey Beekman, University Medical Center Utrecht, Netherlands
Epithelial Organoids as Tools for Discovery in Cystic Fibrosis

Coffee Break

Takanori Takebe, Yokohama City University / Cincinnati Children's Hospital Medical Center, Japan
De novo Generation of Diverse Organ Buds from Stem Cells

Todd C. McDevitt, Gladstone Institutes, USA
Complex Cellular Models of Embryonic Development

Eduardo Marban, Cedars-Sinai Medical Center, USA
Self-Assembling Cardiac Microtissues and their Progeny in Clinical Therapeutics

12:15—17:00
On Own for Lunch

12:15—13:00
Poster Setup

Copley and Singleton Rooms
13:00—22:00
Poster Viewing

Copley and Singleton Rooms
14:30—16:30
Workshop 1: Human iPS Cells in Disease Modeling

Oval Room
* Todd C. McDevitt, Gladstone Institutes, USA

Olga Kashpur, Tufts University, USA
Reprogramming of Diabetic Foot Ulcer Fibroblasts to iPSCs Reveals an Altered Wound Healing Potential

Adriana Blazeski, Johns Hopkins University, USA
Engineered Heart Slices Represent Syncytial Model of Arrhythmogenic Cardiomyopathy

Miguel Angel Hermida, Heriot Watt University, Scotland
3D Printing of Multilineage Human Glioblastoma Models

Alex Ng, Harvard Medical School, USA
Transcription Factor-Wide Engineering of Human Cell Types from Pluripotent Stem Cells

Jeffrey D. Serrill, City of Hope, USA
Using NGN3 Fusion Protein Constructs to Elucidate Optimal Cytoarchitecture in hPSC-Derived Pseudoislets

Kacey Ronaldson, Columbia University, USA
Adult-Like Cardiac Tissue Bio-Engineered From Human Ips Derived Cells Enables Predictive Modeling of Toxicity and Disease

16:30—17:00
Coffee Available

Venetian Room
17:00—19:00
Engineered Organoids for Biological Discovery
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Gary A. Gintant, AbbVie, USA

Anjelica Leticia Gonzalez, Yale University, USA
Interstitial and Microvascular Interfaces in Inflammatory and Fibrotic Disease

Nenad Bursac, Duke University, USA
Microtissues for Studies of Skeletal Muscle Physiology and Disease

Eva-Maria Dehne, TissUse GmbH and Technische Universitat Berlin, Germany
Microphysiological Systems – State of the Art and Future Perspectives

Abhishek Ananthanarayanan, Invitrocue Pte Ltd., Singapore
Short Talk: Hepatocyte Spheroid Cultures in Galactosylated Cellulosic Sponge for Drug DMPK and Efficacy Testing

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Venetian Room
19:30—22:00
Poster Session 1

Copley and Singleton Rooms

SATURDAY, MARCH 11

07:30—08:30
Breakfast

Venetian Room
08:30—11:30
Cell-Based Platforms for Drug Screening
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Nenad Bursac, Duke University, USA

Gary A. Gintant, AbbVie, USA
Development of an in vitro Pro-Arrhythmia Assay

Sharon Presnell, Organovo, Inc., USA
Bioprinting of Liver Organoids

Coffee Break

Milica Radisic, University of Toronto, Canada
Evaluation of Cardiotoxicity Using Biowires

Karl-Heinz Krause, University of Geneva Faculty of Medicine, Switzerland
Engineered Neural Tissues as Human Disease Models

Patrick Guye, InSphero AG, Switzerland
Short Talk: A Microfluidic Multi-Tissue Culturing Platform Based on 3D Microtissue Spheroids

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Copley and Singleton Rooms
13:00—22:00
Poster Viewing

Copley and Singleton Rooms
14:30—16:30
Workshop 2: Career Development
The organizers will facilitate an interactive session on early career development in an effort to enhance the interactions between young and established investigators.

Oval Room
* Laura E. Niklason, Yale University, USA

* Milica Radisic, University of Toronto, Canada

* Nenad Bursac, Duke University, USA

16:30—17:00
Coffee Available

Venetian Room
17:00—19:00
Engineered Tissues in Cancer
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Milica Radisic, University of Toronto, Canada

Biju Parekkadan, Rutgers University, USA
Engineered Cancer-Stroma Microenvironments

Jordan S. Miller, Rice University, USA
Models of Lung Cancer Invasion and Metastasis

Alison P. McGuigan, University of Toronto, Canada
TRACER: An Engineered Tumor for Exploring Cellular Phenotype and Microenvironment in Hypoxic Gradients

Deena Mohamad Ameen Gendoo, Princess Margaret Cancer Centre, Canada
Short Talk: Comprehensive Assessment of the Genetic Landscape of Matched Primary, Xenograft, and Organoid Models for Pancreatic Cancer

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Venetian Room
19:30—22:00
Poster Session 2

Copley and Singleton Rooms

SUNDAY, MARCH 12

07:30—08:30
Breakfast

Venetian Room
08:30—11:30
The Current Wave – Cells as Therapeutics
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Laura E. Niklason, Yale University, USA

Joanne Kurtzberg, Duke University, USA
Game Changers: Using Cord Blood to Help the Brain

Thomas Schulz, ViaCyte, Inc., USA
Development of Stem-Cell Derived, Islet Replacement for Type 1 Diabetes

Coffee Break

Gordana V. Vunjak-Novakovic, Columbia University, USA
Human Cardiac and Tumor Platforms for Study of Disease

Jorge Mansilla-Soto, Memorial Sloan Kettering Cancer Center, USA
Short Talk: CRISPR/Cas9-Targeted Chimeric Antigen Receptor Enhances CAR T Cell-Mediated Tumor Eradication

11:30—17:00
On Own for Lunch

14:30—16:30
Workshop 3: 3-Dimensional Cellular Models

Oval Room
* Laura E. Niklason, Yale University, USA

Amir Ali Khan, University of Sharjah, United Arab Emirates
Unravelling the Gene Expression Profiles of the Early Differentiation of Mesenchymal Stem Cells into Neural Lineage

Sijie Sun, University of Washington, USA
Bioengineering 3D Human Skin Equivalent with Perfused Microvascular Network to Study Host-Viral Interactions During Infection

Christopher Hubert, Cleveland Clinic, Lerner Research Institute, USA
Modeling Glioblastoma through Cancer Stem Cell Organoids

Anastasia Korolj, University of Toronto, Canada
Biomimetic Curvature in Cell Culture Platform Improves Podocyte Differentiation in vitro

Sara Nunes Vasconcelos, University of Toronto, Canada
Diabetes Impairs Arterio-Venous Specification in Engineered Vascular Tissues in a Perivascular Cell Recruitment-Dependent Manner

Ryan LaRanger, University of Texas Southwestern Medical Center, USA
Engineering Reconstituted Decellularized Mouse Lungs with Conditionally Reprogrammed Human Bronchial Epithelial Cells

16:30—17:00
Coffee Available

Venetian Room
17:00—18:45
The Next Wave – Cells as Building Blocks
Meeting has ended...abstracts no longer viewable online.

Oval Room
* Sara Nunes Vasconcelos, University of Toronto, Canada

Miguel Gonzalez-Andrades, Harvard University, USA
Tissue Engineered Corneas: A Clinical Reality?

Daniela Franco Bueno, Institute of Teaching and Research of Sirio Libanes Hospital, Brazil
Alveolar Bone Tissue Engineering for Cleft Lip and Palate

Laura E. Niklason, Yale University, USA
Engineered Arteries in Renal Failure and Arteriosclerosis

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Oval Room
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Venetian Room
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Venetian Room

MONDAY, MARCH 13

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Editas Medicine, Inc. Juno Therapeutics
Merck & Co., Inc. Thermo Fisher Scientific Inc.

We gratefully acknowledge additional support for this conference from:

InSphero Inc.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



AbbVie Inc.


ViaCyte, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

American Association for the Advancement of Science (AAAS)

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676