Keystone Resort Floorplan

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  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

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This meeting took place in 2017


Here are the related meetings in 2018:
New Frontiers in Neuroinflammation: What Happens When CNS and Periphery Meet? (Z4)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Neuroinflammation: Concepts, Characteristics, Consequences (E5)


Organizer(s) Richard M. Ransohoff, Christopher K. Glass and V. Hugh Perry
June 19—23, 2017
Keystone Resort • Keystone, Colorado USA
Discounted Abstract Deadline: Feb 21, 2017
Abstract Deadline: Mar 21, 2017
Scholarship Deadline: Feb 21, 2017
Discounted Registration Deadline: Apr 19, 2017

Sponsored by Biogen, BioLegend, Inc., Ionis Pharmaceuticals, Inc., Shire Human Genetic Therapies and Takeda Pharmaceutical Company Limited

Summary of Meeting:
Neuroinflammation comprises the interaction of two formidably complex organ systems. Two considerations motivate this meeting: first that the communities of neuroscientists and immunologists urgently need to formulate and deploy a joint set of concepts to promote mechanistic progress (hence a meeting of the two), and second that neuroinflammation, broadly conceived, operates throughout life from embryogenesis through old age with consequences bearing on the most serious health concerns ranging from autism and schizophrenia to dementia. What’s needed in this field (for example) is for immunologists to acquire a working knowledge of neuroscience (e.g., electrophysiology, neurotransmitters, behavior) and for neuroscientists to become comfortable with the cells, proteins and animating concepts of contemporary immunology. The optimal venue for such exchange lies in the presentation of compelling multidisciplinary research to a joint audience in the Keystone Symposia format. As such, this meeting aims to: 1) Integrate the intrinsic “immune” elements of the CNS (microglia, complement, certain chemokines) into a broader scheme of neurodevelopment and to indicate where aberrant function of these elements might conduce to neurodevelopmental disorders such as autism; 2) Characterize the neuroinflammatory processes which typify aging and integrate this temporal dynamic into the pathogenesis of neurodegenerative disease; and 3) Share model systems (particularly invertebrate) and technical innovations which can be particularly powerful for generating mechanistic insights into neuroinflammatory processes.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Monday, June 19 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Friday, June 23 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Saturday, June 24 in order to fully experience the meeting.

MONDAY, JUNE 19

16:00—20:00
Arrival and Registration

Keystone Lodge Lobby
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Keystone Lodge-Bighorn Bar

TUESDAY, JUNE 20

07:30—08:30
Breakfast

Longs/Quandary Peaks
08:30—09:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Richard M. Ransohoff, Biogen, USA

Christopher K. Glass, University of California, San Diego, USA
Delineation of an Environment-Dependent Transcriptional Network Specifying Human Microglia Identity

09:30—11:30
Neuroinflammation and Ontogeny
Meeting has ended...abstracts no longer viewable online.

Grays Peak
Richard M. Ransohoff, Biogen, USA
Neuroinflammation: Historical Perspective and Overview

Coffee Break

Marco Prinz, University of Freiburg, Germany
Myeloid Cell Activation and Kinetics in the Brain

Xianhua Piao, Children's Hospital Boston, USA
A GPCR Signaling triad: How Microglia Regulate Myelin Development and Repair

11:30—14:30
On Own for Lunch

11:30—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks
14:30—16:30
Workshop: Microglial Profiles: Time for Your Close-Up!

Grays Peak
* Akihiko Koyama, Eisai Inc., USA

Stephen K. Amoah, University of New Mexico, USA
Effects of Maternal Immune Activation and Hypoxia on Schizophrenia-Related miRNA Expression

Clare Pridans, University of Edinburgh, UK
Csf1r Deficient Rats as a Model for Neurodegeneration

Stefka Gyoneva, Biogen, USA
Context-Dependent Effects of Cx3cr1 Deletion on Microglial Transcriptome

Vladimir Litvak, University of Massachusetts Medical School, USA
Systems Biology of Microglia Signaling in Neuroinflammation

Hansruedi Mathys, Massachusetts Institute of Technology, USA
Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Christopher Bohlen, Stanford University School of Medicine, USA
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-medium Cultures

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Glial Cells of the CNS: Glue No More
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* William S. Talbot, Stanford University School of Medicine, USA

Richard Daneman, University of California, San Diego, USA
Blood-Brain, Endothelial Cells and Pericytes

Brian Popko, University of Chicago, USA
Oligodendrocytes in the Pathogenesis of Multiple Sclerosis

Ethan G. Hughes, University of Colorado Anschutz Medical Campus, USA
Dynamics of NG2+ Glial Cells in the Resting and Damaged Brain

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
19:30—22:00
Poster Session 1

Longs/Quandary Peaks

WEDNESDAY, JUNE 21

07:30—08:30
Breakfast

Longs/Quandary Peaks
08:30—11:30
Neuroinflammation: Phylogeny
Meeting has ended...abstracts no longer viewable online.

Grays Peak
Magdalena Götz, University of Munich, Germany
Mechanism of Scar-Formation – From Zebrafish to Mammals

William S. Talbot, Stanford University School of Medicine, USA
Genetic Control of Microglia Development and Function in Zebrafish

Coffee Break

David A. Wassarman, University of Wisconsin, USA
Neurodegeneration and Innate Immunity in Drosophila

Mary A. Logan, Oregon Health & Science University, USA
Genetic Investigation of Innate Glial Immune Responses in Drosophila

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Transgressions: Immune Molecules in the CNS and Vice Versa
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Angela Vincent, University of Oxford, UK

Lisa M. Boulanger, Princeton University, USA
MHC Class I Immune Proteins in Neuronal Synaptic Transmission, Plasticity, and Disease

Wayne Drevets, Janssen R&D Pharmaceutical Companies of Johnson & Johnson, USA
IL6 and Treatment-Resistant Depression

Anzela Niraula, Ohio State University, USA
Short Talk: Corticosterone Mobilizes Monocytes into Circulation and Induces Endothelial Adhesion Molecule Expression to Cause Monocyte Recruitment to the Brain during Stress

David V. Hansen, Genentech, Inc., USA
Short Talk: Debunking the Myth of Pro-Inflammatory Cytokines in Alzheimer’s Pathology, and Illuminating the Role of TREM2

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
19:30—22:00
Poster Session 2

Longs/Quandary Peaks

THURSDAY, JUNE 22

07:30—08:30
Breakfast

Longs/Quandary Peaks
08:30—11:30
Some Real Immunology for a Change: B Cells and the CNS
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Keiko Ozato, NICHD, National Institutes of Health, USA

Vanda A. Lennon, Mayo Clinic, USA
Neuromyelitis Optica (NMO): An Autoimmune Astrocytopathy

Amit Bar-Or, University of Pennsylvania, USA
Is MS not a T Cell-Mediated Disease?

Coffee Break

Angela Vincent, University of Oxford, UK
Antibodies to Neuronal Receptors and Associated Proteins: Roles, Mechanisms and Challenges

Sara L. Colpitts, Dartmouth College, USA
Short Talk: Regulatory B Cell Induction by a Human Gut Commensal Antigen Protects Against CNS Inflammation and Demyelination

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Cool Stuff: New Techniques
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Magdalena Götz, University of Munich, Germany

Knut Biber, Universitätsklinikum, Germany
Microglia-Replenished OHSC: A Culture System to Study in vivo-Like Adult Microglia

Milos Pekny, University of Gothenburg, Sweden
3D Cultures: Letting Neural Cells Stretch Out and Breathe

Akihiko Koyama, Eisai Inc., USA
Immunodementia: A Multidisciplinary Approach

Carlo Condello, University of California, San Francisco, USA
Short Talk: Non-Invasive Bioluminescent Imaging of Astrocytic Gliosis Reveals Disease Progression and Drug Efficacy in Alzheimer's Mouse Models

Carleton Goold, Novartis Institutes of Biomedical Research, USA
Short Talk: Gene-Edited Human Stem Cell Models of Tuberous Sclerosis Exhibit Treatable Disease Phenotypes upon 2D and 3D Neuronal Differentiation

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
19:30—22:00
Poster Session 3

Longs/Quandary Peaks

FRIDAY, JUNE 23

07:30—08:30
Breakfast

Longs/Quandary Peaks
08:30—11:30
It’s About Time: Neuroinflammation Across the Lifespan
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Suman Jayadev, University of Washington, USA

Staci Bilbo, Harvard Medical School/MGH, USA
Environmental Effects on Development Transduced through Neuroinflammation

David Edwards, King's College London, UK
Neuroanatomical Effects of Prematurity

Coffee Break

Edith Hamel, McGill University, Canada
Inflammation and Vascular Factors in Dementia

Carina Block, Duke University, USA
Short Talk: Prenatal Air Pollution and Maternal Stress Alters Early Communication, Microglia and Synapse Number in Developing Offspring

11:30—17:00
On Own for Lunch

14:30—16:00
Panel: Looking Backwards and Forwards: Lessons Learned and Suggestions for Improvement
This innovative panel discussion will be composed of and driven by postdocs and students. The panel will present their learnings (scientific and other) from the symposium, and provide suggestion to modify the format or content. Questions and comments from the audience will enrich the experience. Keystone Symposia staff will ensure these observations are considered for implementation at future conferences.

Grays Peak
* Richard M. Ransohoff, Biogen, USA

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—18:45
Type I Interferon in CNS Physiology and Pathophysiology
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Irene Knuesel, Roche Innovation Center Basel, Switzerland

V. Hugh Perry, University of Southampton, UK
Microglia, the Cornerstone of Neuroinflammation

Marina Lynch, Trinity College Dublin, Ireland
TLR2 Activation and its Effects on Hippocampal Function

Marcus Kaul, Sanford-Burnham Medical Research Institute, USA
Short Talk: Neuroprotection by IFNβ in a Murine Model of HIV-1 Associated Brain Injury

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Grays Peak
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs/Quandary Peaks
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Longs/Quandary Peaks

SATURDAY, JUNE 24

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Biogen BioLegend, Inc.
Ionis Pharmaceuticals, Inc. Shire Human Genetic Therapies
Takeda Pharmaceutical Company Limited
 

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

CEDARLANE

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

American Association for the Advancement of Science (AAAS) American Association for the Advancement of Science (AAAS)

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676