NOTES:
This meeting occurs in 2018.
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


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Therapeutic Targeting of Hypoxia-Sensitive Pathways (V1)

Scientific Organizers: Chris W. Pugh, Pablo Wappner, Johanna Myllyharju and Moira K. Whyte


April 10—14, 2018

University of Oxford-Mathematical Institute, Oxford, UK


Supported by the Directors' Fund


BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
Scholarship Deadline: Dec 11, 2017 [details]
Discounted Abstract Deadline: Dec 11, 2017 [details]
Abstract Deadline: Jan 10, 2018 [details]
Discounted Registration Deadline: Feb 13, 2018 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2018-V1 "Therapeutic Targeting of Hypoxia-Sensitive Pathways" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On December 11, 2017 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After December 11, 2017 until January 10, 2018 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
December 11, 2017 n/a
Discounted NON-STUDENT Registration
More details
Before and On February 13, 2018 920.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After February 13, 2018 1120.00 USD
Discounted STUDENT Registration
More details
Before and On February 13, 2018 695.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After February 13, 2018 895.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.

Apply for a Scholarship



Discounted Abstract Deadline: December 11, 2017


Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is January 10, 2018)

Global Health Travel Award Deadline:


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: December 11, 2017


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: January 10, 2018


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is December 11, 2017)

Discounted Registration Deadline: February 13, 2018


Registration Fee: 920.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 695.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1120.00 USD*
Student Registration Fee: 895.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.

Meeting Summary



Tissue oxygen gradients contribute to morphogenesis and in health, cells in different tissues function under differing ambient oxygen conditions. Diseases or environmental challenges can reduce oxygen supply or increase demand, resulting in tissue hypoxia. Adaptive mechanisms have evolved that range from almost instantaneous acute ventilatory changes, through transcriptional events entrained in hours, to epigenetic events with slower effects and genetic adaptations selected across species and over generations. The role of the 2-oxoglutarate dependent dioxygenase enzyme family in influencing many, but not all, of these pleiotropic processes is increasingly recognized, and drugs targeting these enzymes are being evaluated in both experimental and clinical settings. The conference combines the Keystone Symposia brand with the European HypoxiaNET consortium to bring together experts in hypoxia biology from clinical, academic and industrial backgrounds, including trainees, to: 1) Address gaps in our knowledge of responses to hypoxia across these timeframes and in different tissues; 2) Benefit the field by sharing techniques and reagents to enhance therapeutic targeting of the hypoxic response in general, including via inhibition of oxygen-sensitive enzymes; 3) Consider the utility of harnessing these pathways in organ dysfunction, in regenerative medicine and to influence immune and inflammatory responses; and 4) Disseminate outcomes of ongoing clinical trials and enhance plans for future trials. The most important anticipated outcome from the conference is that, through sharing knowledge, enhancing collaborations and training participants from diverse backgrounds, the likelihood of successful manipulation of hypoxia pathways to produce clinical benefits in a variety of fields including, but not restricted to, renal anaemia will be significantly enhanced.