INEC Killarney Convention Centre Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Positive-Strand RNA Viruses (E2)

Scientific Organizers: Frank van Kuppeveld and Andrea Gamarnik


June 9—13, 2019

INEC Killarney Convention Centre, Killarney, Co. Kerry, Ireland


Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Global Health Travel Award Deadline: Jan 8, 2019 [details]
Scholarship Deadline: Feb 7, 2019 [details]
Discounted Abstract Deadline: Feb 7, 2019 [details]
Abstract Deadline: Mar 6, 2019 [details]
Discounted Registration Deadline: Apr 9, 2019 [details]

If you have missed a deadline due to the US government shutdown, please contact our office.

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2019-E2 "Positive-Strand RNA Viruses" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On February 7, 2019 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After February 7, 2019 until April 28, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
February 7, 2019 n/a
Discounted NON-STUDENT Registration
More details
Before and On April 9, 2019 945.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After April 9, 2019 1145.00 USD
Discounted STUDENT Registration
More details
Before and On April 9, 2019 720.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After April 9, 2019 920.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: February 7, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is March 6, 2019)

Global Health Travel Award Deadline: January 8, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: February 7, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: March 6, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is February 7, 2019)

Discounted Registration Deadline: April 9, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 945.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1145.00 USD*
Student Registration Fee: 920.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 24 hr (international) time


The meeting will begin on Sunday, June 9 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, June 13 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, June 14 in order to fully experience the meeting.

SUNDAY, JUNE 9

4:00—8:00 PM
Arrival and Registration

INEC Foyer
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

INEC Foyer

MONDAY, JUNE 10

8:30—9:30 AM
Welcome and Keynote Address
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Frank van Kuppeveld, Utrecht University, Netherlands

* Andrea Gamarnik, Fundación Instituto Leloir, Argentina

Michael S. Diamond, Washington University School of Medicine, USA
Receptor Hunting for Alphaviruses: A Travel Through Time

9:30—11:45 AM
The Virosphere and the Virome
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Alexander E. Gorbalenya, Leiden University Medical Center, Netherlands

* Andrew E. Firth, University of Cambridge, UK

Eugene V. Koonin, National Institutes of Health, USA
Evolution of the RNA Virosphere: Towards a Global Picture

Coffee Break

Julie K. Pfeiffer, University of Texas Southwestern Medical Center, USA
Origins of Animal Innate Immunity

Marilyn J. Roossinck, Pennsylvania State University, USA
Viruses as Symbionts

Vyacheslav Yurchenko, University of Ostrava, Czech Republic
Short Talk: Positive-Strand RNA Viruses in Trypanosomatid Parasites

11:45 AM—5:00 PM
On Own for Lunch

11:45 AM—1:00 PM
Poster Setup

1st Floor INEC
1:00—10:00 PM
Poster Viewing

1st Floor INEC
2:30—4:30 PM
Workshop 1: Burning Questions, Opportunities and Challenges in RNA Virology

INEC Main Auditorium
* Eric J. Snijder, Leiden University Medical Center, Netherlands

Ralf Bartenschlager, Heidelberg University, Germany
Resolved and Future Research Challenges of Plus-Strand RNA Virus Replication Strategies

Peter Sarnow, Stanford University School of Medicine, USA
Changing the Shape of Viral RNA to Subvert Host Pathways

Drew Weissman, University of Pennsylvania, USA
mRNA-Based Vaccines and Therapeutics – Advances and Challenges

Ann Palmenberg, University of Wisconsin-Madison, USA
Women: Plurality or Equality?

4:30—5:00 PM
Coffee Available

INEC Foyer
5:00—7:00 PM
Virus Structure and Entry
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Toby Tuthill, Pirbright Institute, UK

* Berend Jan Bosch, Utrecht University, Netherlands

Susan Hafenstein, Pennsylvania State University, USA
Enterovirus Structure / Entry

David Veesler, University of Washington, USA
Structural Studies of Coronavirus Spike Glycoroteins

Shee-Mei Lok, Duke-NUS Medical School, Singapore
Capsid Protein Structure in Zika Virus Reveals the Flavivirus Assembly Process

Richard J. Kuhn, Purdue University, USA
Short Talk: Budding Induces Symmetry Defects in Flavivirus Virions

Yifei Lang, Utrecht University, Netherlands
Short Talk: Betacoronavirus S and HE Proteins are in Functional Balance: Evidence for Convergent Evolution of Betacorona and Influenza Viruses

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

INEC Foyer
7:30—10:00 PM
Poster Session 1

1st Floor INEC

TUESDAY, JUNE 11

8:30—11:30 AM
RNA Structure and Function
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Diego Alvarez, Universidad Nacional de San Martín, Argentina

* Ian Goodfellow, University of Cambridge, UK

Andrea Gamarnik, Fundación Instituto Leloir, Argentina
Function and Evolution of RNA Structures in the Flavivirus Genome

Jeffrey S. Kieft, University of Colorado School of Medicine, USA
Understanding Viral RNA Function by Linking Structural Biology to Virology

Coffee Break

Stacy M. Horner, Duke University Medical Center, USA
RNA Modifications Go Viral

Anna Marie Pyle, Yale University, USA
Regulatory Structures in Viral RNA Genomes

Omer Ziv, University of Cambridge, UK
Short Talk: RNA Communication between Viruses and their Hosts

Rebecca S. Brown, Albert Einstein College of Medicine, USA
Short Talk: PAR-CLIP Analysis of the Alphavirus Capsid Protein Demonstrates Unique Recognition of the Genomic RNA

11:30—11:45 AM
European Virus Archive

INEC Main Auditorium
Christine MA Prat, European Virus Archive, France

11:30 AM—5:00 PM
On Own for Lunch

11:30 AM—1:00 PM
Poster Setup

1st Floor INEC
1:00—10:00 PM
Poster Viewing

1st Floor INEC
2:00—4:30 PM
Workshop 2

INEC Main Auditorium
* Anna K. Overby, Umeå University, Sweden

* Eric Jan, University of British Columbia, Canada

Alexander E. Gorbalenya, Leiden University Medical Center, Netherlands
Domain Linkage in the Largest Expansion of RNA Virus Genomes

Benjamin Götte, Karolinska Institutet, Sweden
Separate Domains of G3BP Promote Efficient Clustering of Alphavirus Replication Complexes and Recruitment of the Translation Initiation Machinery

Jelke J. Fros, Wageningen University, Netherlands
Newly Discovered Antiviral Pathways Control RNA Virus Replication and Drive Virus Evolution

Holly Ramage, University of Pennsylvania, USA
Using Proteomics Tools to Discover New Mechanisms in Flaviviral Infection

Montserrat Barcena, Leiden University Medical Center, Netherlands
The Origin of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy

Thomas Morrison, University of Colorado School of Medicine, USA
Scavenger Receptors on Liver Phagocytes Mediate Clearance of Blood-Borne Alphaviruses through Recognition of Modified Lysine Residues in Viral Glycoproteins

Colin Xinru Cheng, Duke-NUS Medical School, Singapore
Impact of Nuclear vs Cytoplasmic Localisation of Dengue Virus NS5

Jing Jin, Vitalant Research Institute, USA
Antigen-Crosslinking Dependent Antiviral Mechanisms

Lisa Chon Lindesmith, University of North Carolina at Chapel Hill, USA
Molecular Delineation of the Serum Antibody Repertoire Reveals Structural Mechanisms for Broad Antibody Responses following Human Norovirus Vaccination

Alexander A. Khromykh, University of Queensland, Australia
Determinants of Zika Virus Host Tropism Uncovered by Deep Mutational Scanning

4:30—5:00 PM
Coffee Available

INEC Foyer
5:00—7:00 PM
Virus Replication, Evolution and Virus-Cell Interactions
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Jason Mackenzie, University of Melbourne, Australia

* Volker Lohmann, Heidelberg University, Germany

Frank van Kuppeveld, Utrecht University, Netherlands
A Novel Viral Mechanism to Prevent Translation Inhibition and Activation of the Integrated Stress Response

Peter D. Nagy, University of Kentucky, USA
Viral and Host Players in Tombusvirus Replication

Raul Andino, University of California, San Francisco, USA
Virus Evolution: Math, Experiments and Consequences

Karim Majzoub, Stanford University, USA
Short Talk: An RNA-Centric Dissection of Host Complexes Controlling Flavivirus Infection

Robert N. Kirchdoerfer, The Scripps Research Institute, USA
Short Talk: Structure of the SARS-CoV NSP12 Polymerase Bound to NSP7 and NSP8 Co-Factors

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

INEC Foyer
7:30—10:00 PM
Poster Session 2

1st Floor INEC

WEDNESDAY, JUNE 12

8:30—11:30 AM
Immunology of Infection and Viral Evasion Mechanisms
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Susan C. Baker, Loyola University Chicago, USA

Michaela U. Gack, University of Chicago, USA
Intracellular Virus Sensing Pathways and Viral Evasion Strategies

Marlène Dreux, INSERM U758, France
Plasmacytoid Dendritic Cells and Infected Cells form an Interferogenic Synapse Required for Antiviral Responses

Coffee Break

Sujan Shresta, La Jolla Institute for Immunology, USA
Antigenic Cross-Reactivity between Dengue and Zika Viruses: Time for a Pan-Flavivirus Vaccine?

Stephanie Karst, University of Florida, USA
The Influence of the Intestinal Microbiota on Norovirus Pathogenesis

Jason Mackenzie, University of Melbourne, Australia
Short Talk: Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis

* Ana Fernandez-Sesma, Mount Sinai School of Medicine, USA
Short Talk: High-Dimensional CyTOF Analysis of Dengue Virus Infected Human DCS Reveals Distinct Viral Signatures

11:30 AM—12:00 PM
The Virus Pathogen Resource (ViPR)
ViPR is a freely-available NIH/NIAID-funded online Bioinformatics Resource Center supporting viral pathogen research. ViPR provides access to sequence records, immune epitopes and 3D protein structures, and unique annotations generated from ViPR bioinformatics pipelines including genotype/subtype assignments, mature peptide predications and sequence feature variant types. ViPR also provides analysis tools and supports many analysis workflows, including metadata/subtype-based genome and mature peptide sequence search, phylogenetic analysis with metadata/subtype visualization, sequence variation analysis using various approaches, and more. This workshop will provide a live demonstration of ViPR’s major search and analysis capabilities through a Zika virus use case.

INEC Main Auditorium
Yun Zhang, J. Craig Venter Institute, USA

11:30 AM—5:00 PM
On Own for Lunch

11:30 AM—1:00 PM
Poster Setup

1st Floor INEC
1:00—10:00 PM
Poster Viewing

1st Floor INEC
2:00—4:30 PM
Workshop 3

INEC Main Auditorium
* Vineet D. Menachery, University of Texas Medical Branch, USA

* Gregory D. Ebel, Colorado State University, USA

Kelly Watters, University of Wisconsin, USA
CDHR3 Extracellular Domain EC1 Mediates Rhinovirus C Attachment to Cells and its Recombinant Derivatives Inhibit Virus Infection

Mayra Alejandra Diosa-Toro, Duke-NUS Medical School, Singapore
Identification and Characterization of Mosquito RNA-Binding Proteins that Regulate Dengue Virus Infection

Christopher J. Neufeldt, University of Heidelberg, Germany
ER-Shaping Atlastin Proteins Differentially Contribute to Flavivirus Replication and Assembly

Rushika Perera, Colorado State University, USA
Host Metabolism: Friend or Foe in Flavivirus Biogenesis and Disease

Jana Van Dycke, KU Leuven – Rega Institute, Belgium
Zebrafish Larvae as an in vivo Replication Model of Human Norovirus

Marjolein Kikkert, Leiden University Medical Center, Netherlands
The Deubiquitinating Activity of Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Contributes to Innate Immune Evasion and Enhances Viral Virulence

Kizzmekia S. Corbett, NIAID, National Institutes of Health, USA
Prefusion MERS Coronavirus Spike Trimer Vaccination Elicits Protective Antibodies Targeting Epitopes Outside of Receptor Binding Domain

Lara J. Herrero, Griffith University, Australia
Alphaviruses and Chondrocytes: New Insights into the Mechanisms of Viral Arthritic Disease

Maria Isabel Giraldo, University of Texas Medical Branch, USA
Flavivirus Envelope Protein Ubiquitination Drives Virus Entry and Pathogenesis

Gorben Pijlman, Wageningen University, Netherlands
Subgenomic Flavivirus RNA Binds the Antiviral Mosquito DEAD/H-Box Helicase ME31B and Determines Zika Virus Transmission by Aedes Aegypti

4:30—5:00 PM
Coffee Available

INEC Foyer
5:00—7:00 PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Stanley Perlman, University of Iowa, USA

Davide Corti, Humabs BioMed SA, Switzerland
Passive Antibody Therapies Against Endemic, Emerging and Re-Emerging Infectious Diseases

Alexander Ploss, Princeton University, USA
Model Systems to Assess Vaccine-Induced Immune Responses in vivo

Bali Pulendran, Stanford University School of Medicine, USA
Probing the Immune Response to Vaccination with Systems Based Approaches

* Priscilla L. Yang, Harvard Medical School, USA
Short Talk: Targeted Protein Degradation as an Antiviral Strategy

Lucia Carrau, Institut Pasteur, France
Short Talk: Chikungunya virus Vaccine Candidates with Decreased Mutational Robustness are Attenuated in vivo and have Compromised Transmissibility

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

INEC Foyer
7:30—10:00 PM
Poster Session 3

1st Floor INEC

THURSDAY, JUNE 13

8:00—8:30 AM
Poster Setup

1st Floor INEC
8:30 AM—5:00 PM
Poster Viewing

1st Floor INEC
8:30—11:30 AM
Virus Transmission, Tropism and Pathogenesis
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Ricardo Rajsbaum, University of Texas Medical Branch, USA

Carolyn B. Coyne, University of Pittsburgh, USA
The Role of the Neonatal Fc Receptor in Echovirus Entry and Pathogenesis.

Christian Drosten, Charité - Universitätsmedizin Berlin, Germany
Ecology, Inter-species Transmission, and Pathogenic Potential of Emerging Coronaviruses

Coffee Break

Diane E. Griffin, Johns Hopkins Bloomberg School of Public Health, USA
Role of Alphavirus nsP3 in Replication and Neurovirulence

Xiang-Jin Meng, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, USA
Hepatitis E Virus: The Ever-Expanding Host Range and Cross-Species Infection

* Eva Harris, University of California, Berkeley, USA
Short Talk: Molecular Mechanisms and Determinants of Flavivirus NS1-Induced Endothelial Permeability, Vascular Leak, and Virus Dissemination

Stacey Lynne Schultz-Cherry, St. Jude Children's Research Hospital, USA
Short Talk: Astrovirus Capsid is a Novel Viral Enterotoxin

11:30 AM—12:30 PM
Lunch

INEC Foyer
12:00—2:30 PM
Poster Session 4

1st Floor INEC
4:30—5:00 PM
Coffee Available

INEC Foyer
5:00—6:45 PM
Invertebrate Viruses and their Vectors
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
* Gorben Pijlman, Wageningen University, Netherlands

* Laura D. Kramer, Wadsworth Center, NYSDOH; SUNY Albany, USA

Erol Fikrig, Yale University School of Medicine, USA
Aedes aegypti AgBR1 Influences Early Zika Virus Infection

Maria-Carla Saleh, Institut Pasteur, France
Principal Components of Innate Immunity Pathways Constrain Viral Evolution

Ronald P. van Rij, Radboud University Medical Center, Netherlands
Biogenesis and Functions of Virus and Host-Derived piRNAs in Vector Mosquitoes

Diego Alvarez, Universidad Nacional de San Martín, Argentina
Short Talk: RNA Recombination Allows Chikungunya Virus to Overcome Barriers Imposed during Mosquito Transmission

6:45—7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 05/09/2019

INEC Main Auditorium
7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

INEC Foyer
8:00—11:00 PM
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

INEC Foyer

FRIDAY, JUNE 14

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Bill & Melinda Gates Foundation

We gratefully acknowledge additional support from these exhibitors at this conference:

European Virus Archive
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge additional support for this conference from:

American Society of Gene & Cell Therapy (ASGCT) GeneTex, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179