Herrenhausen Palace Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Pushing the Limits of Healthspan and Longevity (D3)

Scientific Organizers: Rochelle Buffenstein, Holly Brown-Borg and Colin Selman


April 15—19, 2018

Herrenhausen Palace, Hannover, Germany


Local Co-Organizer: Martin S. Denzel, Max Planck Institute for Biology of Aging.
In cooperation with Volkswagen Foundation


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for oral short talks. Abstracts for poster display opportunities will be accepted until 6 weeks before meeting start date midnight MST.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Dec 12, 2017 [details]
Discounted Abstract Deadline: Dec 12, 2017 [details]
Abstract Deadline: Jan 10, 2018 [details]
Discounted Registration Deadline: Feb 13, 2018 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2018-D3 "Pushing the Limits of Healthspan and Longevity" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On December 12, 2017 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After December 12, 2017 until March 4, 2018 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
December 12, 2017 n/a
Discounted NON-STUDENT Registration
More details
Before and On February 13, 2018 920.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After February 13, 2018 1120.00 USD
Discounted STUDENT Registration
More details
Before and On February 13, 2018 695.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After February 13, 2018 895.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: December 12, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is January 10, 2018)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: December 12, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: January 10, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is December 12, 2017)

Discounted Registration Deadline: February 13, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 920.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 695.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1120.00 USD*
Student Registration Fee: 895.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 24 hr (international) time


The meeting will begin on Sunday, April 15 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 19 with a closing plenary session from 16:00 to 18:00, followed by dinner. We recommend return travel on Friday, April 20 in order to fully experience the meeting.

SUNDAY, APRIL 15

4:00—8:00 PM
Arrival and Registration

Grand Mussmann Hotel, Tivoli Room
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Central-Hotel Kaiserhof

MONDAY, APRIL 16

8:30—9:30 AM
Welcome and Keynote Address
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Controlling Metabolism during Aging, Role of Insulin and Adipose Depots

9:30 AM—12:00 PM
Communicating to Save Thyself: Is a Single Signaling Path the Answer?
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Holly M. Brown-Borg, University of North Dakota School of Medicine, USA
Growth Hormone Signaling and Longevity

Coffee Break

Dominic J. Withers, Imperial College London, UK
Manipulation of mTOR: Is this the Holy Grail for Healthy Aging

Reinhold G. Erben, University of Veterinary Medicine Vienna, Austria
Role of the Klotho/FGF23 Signaling Axis in Aging

Paul L. Fox, Lerner Research Institute, USA
Short Talk: Glutamyl-Prolyl tRNA Synthetase is a Critical mTORC1-S6K1 Target Determining Adiposity and Lifespan in Mice

Christopher G. Proud†, SAHMRI, Australia
Short Talk: Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Lifespan

12:00—1:00 PM
Lunch

Ballroom
12:30—1:00 PM
Poster Setup

Ballroom
1:00—7:30 PM
Poster Viewing

Ballroom
1:00—3:30 PM
Poster Session 1

Ballroom
3:30—4:00 PM
Coffee Available

Foyer
4:00—6:00 PM
Good Fat, Bad Fat, Brown Fat, White Fat….
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Elisabetta Mueller, New York University, USA
Talk Title to be Announced

Barbara Cannon, Stockholm University, Sweden
Environmental Temperature and Longevity

John Speakman, Institute of Genetics and Developmental Biology, CAS, China
Does Dietary Protein Content Leverage Total Food Intake and Hence Drive Obesity?

Jan Nedergaard, Stockholm University, Sweden
Short Talk: Enhanced ROS Production in Mitochondria from Prematurely Aging mtDNA Mutator Mice

6:00—7:30 PM
Dinner
No registration fees are used to fund alcohol served at this function.

Ballroom

TUESDAY, APRIL 17

8:30—11:45 AM
Trash Removal: Is Enhanced Proteostasis the Way Forward in Aging
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Rochelle Buffenstein, Calico Life Sciences LLC, USA
Extreme Longevity in Naked Mole-Rats is Associated with Upregulated Proteostasis

Martin S. Denzel, Max Planck Institute for Biology of Aging, Germany
Forward Genetic Approaches Reveal Multi-Layered Regulation of the Hexosamine Pathway that Modulates Protein Quality Control

Coffee Break

Karyn L. Hamilton, Colorado State University, USA
Contribution of Changes in Cell Proliferation to Proteostasis in Long-Lived Models

Louis R. Lapierre, Brown University, USA
A Novel and Druggable Modulator of HLH-30/TFEB, Autophagy and Lifespan

Fabian Finger, Institute for Genetics and CECAD Research Center, Germany
Short Talk: Food Perception through a Pair of Olfactory Neurons Triggers Rewiring of Organismal Proteostasis

Mario Ost, German Institute of Human Nutrition, Germany
Short Talk: Elevated FGF21 during Aging is Required to Preserve Hepatic Proteostasis and Metabolic Health

11:45 AM—1:00 PM
Lunch

Ballroom
12:30—1:00 PM
Poster Setup

Ballroom
1:00—7:30 PM
Poster Viewing

Ballroom
1:00—3:30 PM
Poster Session 2

Ballroom
3:30—4:00 PM
Coffee Available

Foyer
4:00—6:00 PM
Powerhouse of the Cell: Manipulating Energy in Aging
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
William B. Mair, Harvard School of Public Health, USA
Mitochondrial Dynamics and Healthy Aging

Susanne Klaus, German Institute of Human Nutrition, Germany
Mitochondrial Uncoupling, Diet, and Aging in Mice

Hazel H. Szeto, Weill Cornell Medical College, USA
Novel Peptides Target Cellular Powerhouses to Delay Aging and Mitigate Age-Related Chronic Conditions

Fernanda Marques da Cunha, Federal University of São Paulo, Brazil
Short Talk: Mitochondrial Effects of Life Span-Extending Interventions in Caenorhabditis elegans

6:00—7:30 PM
Dinner
No registration fees are used to fund alcohol served at this function.

Ballroom

WEDNESDAY, APRIL 18

8:30—11:45 AM
Changing what and how we Eat and its Impact upon Healthspan
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Colin Selman, University of Glasgow, UK
The Influence of Genetic Background on the Metabolic Responsiveness to Dietary Restriction in Mice

Olivia Casanueva, Babraham Institute, UK
Global and Dynamic Metabolic Remodelling Events in Long-lived C. elegans

Coffee Break

Matthew Piper, Monash University, Australia
The Role of Amino Acid Balance in Lifespan and Health in Drosophila

Samantha Marie Biet, University of Sydney, Australia
Extending Healthspan and Lifespan: Insights From Nutritional Geometry

Olga Spadaro, Yale University, USA
Short Talk: Caloric Restriction in Humans Inhibits Inflammation: Insights from CALERIE-II

YongTian Liang, Free University of Berlin, Germany
Short Talk: Spermidine and Dietary Restriction Converging on Mitochondrial Metabolism in a Model of Cognitive Aging

11:45 AM—1:00 PM
Lunch

Ballroom
12:30—1:00 PM
Poster Setup

Ballroom
1:00—7:30 PM
Poster Viewing

Ballroom
1:00—3:30 PM
Poster Session 3

Ballroom
3:30—4:00 PM
Coffee Available

Foyer
4:00—6:00 PM
Swords, Targets and Cell Death: Combatting Senescence
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Judith Campisi, Buck Institute for Research on Aging, USA
Cellular Senescence: A Double-edged Sword

Claude Jourdan Le Saux, University of California, San Francisco, USA
The Role of Senescent Cells in Aged and Fibrotic Lungs

Nathan K. LeBrasseur, Mayo Clinic, USA
Senolytic Mechanism to Extend Healthspan

Anil Bhushan†, University of California, San Francisco, USA
Short Talk: Eliminating senescent beta cells prevent Type 1 Diabetes

6:00—7:30 PM
Dinner
No registration fees are used to fund alcohol served at this function.

Ballroom

THURSDAY, APRIL 19

8:30—11:45 AM
A View from Above: Aging at the Top of the Food Chain
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Riikka Hamalainen, University of Eastern Finland, Finland
Mitochondrial DNA mutagenesis and aging

P. Eline Slagboom, Leiden University, Netherlands
Talk Title to be Announced

Coffee Break

Maiken Nedergaard, University of Rochester, USA
The Gymphatic System

Alexander Bürkle, University of Konstanz, Germany
Biomarkers of Human Ageing – The EU FP7 MARK-AGE Project and Beyond

Pénélope Andreux, Amazentis, Switzerland
Short Talk: Orally Administered Urolithin A is Safe and Modulates Muscle and Mitochondrial Biomarkers in Elderly

Ian R. Lanza, Mayo Clinic College of Medicine, USA
Short Talk: Therapeutic Potential of Dietary Omega-3 Fatty Acids in Aging Skeletal Muscle

11:45 AM—1:00 PM
Lunch

Ballroom
1:30—3:30 PM
Workshop

Auditorium
David A. Ferenbach, University of Edinburgh, UK
The Impact of a Young Circulation on Renal Injury and Fibrosis in Aged Mice

Zoe E. Gillespie, University of Saskatchewan, Canada
Metformin Treatment and Amino Acid Restriction Induce Progerin Degradation in Hutchinson-Gilford Progeria Syndrome Fibroblasts

Samir Morsli, University of Sheffield, UK
Establishing a Model of Stress-Induced Senescence in Zebrafish Larvae

Teresa G. Valencak, Veterinary University Vienna, Austria
Becoming Obese and Hyperthermic en Miniature in Ames Dwarf Mice (Prop1 df/df)

Reza Esmaillie, University of Cologne, Germany
Dissecting the Role of Hypoxia-Signaling in Extracellular Matrix Formation of the Nematode

Johannes Grillari, BOKU - University of Natural Resources and Applied Life Sciences Vienna, Austria
Extracellular Vesicles and their miRNA Cargo in Aging and Age-Associated Diseases

Irina G. Shabalina, Stockholm University, Sweden
Upregulated Cytochrome b5 May Rescue Normal Androgen Production in Mitochondrial Respiratory Chain Deficient Leydig Cells from Prematurely Aging Mice

Asael Roichman, Bar Ilan, Israel
SIRT6 Controls Energy Metabolism to Regulate Lifespan and Healthspan

3:30—4:00 PM
Coffee Available

Foyer
4:00—5:45 PM
Drugging Aging - Interventions to Extend Human Health and Lifespan
Registered attendees can view abstracts starting on 03/15/2018

Auditorium
Andrew Phillips, C4 Therapeutics, USA
Targeted Protein Degradation

David Gems, University College London, UK
What is an Anti-Aging Drug?

Pedro Beltran, UNITY Biotechnology, USA
Senolytic Drugs: From Mutant Mice to Human Clinical Trials

5:45—6:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 03/15/2018

Ballroom
6:00—7:30 PM
Dinner
No registration fees are used to fund alcohol served at this function.

Ballroom

FRIDAY, APRIL 20

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks the Volkswagen Foundation for generously supporting this meeting:

in Cooperation with Volkswagen Foundation
 

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Zymo Research Corporation

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676