Beaver Run Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Cancer Epigenetics: New Mechanisms, New Therapies (B4)

Scientific Organizers: François Fuks and Anne Brunet


February 10—14, 2018

Beaver Run Resort, Breckenridge, Colorado, USA


Sponsored by Cancer Research UK, Cell Research, Incyte Corporation, Merck & Co., Inc., Novartis Institutes for BioMedical Research, Pfizer Inc. and Roche


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Oct 10, 2017 [details]
Discounted Abstract Deadline: Oct 10, 2017 [details]
Abstract Deadline: Nov 8, 2017 [details]
Discounted Registration Deadline: Dec 12, 2017 [details]

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2018-B4 "Cancer Epigenetics: New Mechanisms, New Therapies" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On October 10, 2017 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After October 10, 2017 until December 30, 2017 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
October 10, 2017 n/a
Discounted NON-STUDENT Registration
More details
Before and On December 12, 2017 820.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After December 12, 2017 1020.00 USD
Discounted STUDENT Registration
More details
Before and On December 12, 2017 595.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After December 12, 2017 795.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: October 10, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is November 8, 2017)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: October 10, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: November 8, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is October 10, 2017)

Discounted Registration Deadline: December 12, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 820.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 595.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1020.00 USD*
Student Registration Fee: 795.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 24 hr (international) time


The meeting will begin on Saturday, February 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Wednesday, February 14 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Thursday, February 15 in order to fully experience the meeting.

SATURDAY, FEBRUARY 10

4:00—8:00 PM
Arrival and Registration

Foyer
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Foyer

SUNDAY, FEBRUARY 11

7:00—8:00 AM
Breakfast

Summit Gallery
8:00—9:00 AM
Welcome and Keynote Address
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* François Fuks, Université libre de Bruxelles, Belgium

* Anne Brunet, Stanford University, USA

Tony Kouzarides, University of Cambridge, UK
Modifications of RNA: Their Function and Role in Cancer

9:00—11:30 AM
Epigenetic Mechanisms and Cancer
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Anne Brunet, Stanford University, USA

Geneviève Almouzni, Centre National de la Recherche Scientifique, France
Chromatin Determinants of Centromeric Identity and their Deregulation in Cancer

Adrian P. Bracken, Trinity College Dublin, Ireland
Short Talk: A New Family of Vertebrate-Specific Polycombs Balance PRC2 Subtype Activities

Coffee Break

François Fuks, Université libre de Bruxelles, Belgium
Transcriptome-Wide Distribution and Function of RNA Modifications in Cancer

Panagiotis Ntziachristos, Northwestern University, USA
Short Talk: Active Deubiquitination as a Molecular Rheostat Controlling Resistance to Therapy in Acute Leukemia

Shelley L. Berger, University of Pennsylvania, USA
Epigenetic Pathways as Targets in Human Cancer

11:30 AM—5:00 PM
On Own for Lunch

11:30 AM—1:00 PM
Poster Setup

Breckenridge Ballroom
1:00—10:00 PM
Poster Viewing

Breckenridge Ballroom
4:30—5:00 PM
Coffee Available

Foyer
5:00—7:30 PM
Chromatin Dysregulations in Cancer
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Johnathan R. Whetstine, Massachusetts General Hospital, USA

Luciano Di Croce, Centre for Genomic Regulation, Spain
Role of Polycomb and MLL Complexes in Nuclear Architecture and Gene Regulation

Cigall Kadoch, Dana-Farber Cancer Institute, Harvard Medical School, USA
BAF Complex Structure and Function in Human Cancer

Tom Owen-Hughes, University of Dundee, Scotland
Short Talk: Variation in the Protein Composition of SWI/SNF Chromatin Remodeling Complexes in Clear Cell Renal Carcinoma

Ozgur Oksuz, New York University School of Medicine, USA
Capturing the Onset of Polycomb Domain Formation

William J. Greenleaf, Stanford University, USA
ATAC-ing Gene Regulation in Cancer and Development

7:30—8:30 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
7:30—10:00 PM
Poster Session 1

Breckenridge Ballroom

MONDAY, FEBRUARY 12

7:00—8:00 AM
Breakfast

Summit Gallery
8:00—11:15 AM
Emergence of Epitranscriptomics
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Cigall Kadoch, Dana-Farber Cancer Institute, Harvard Medical School, USA

Lu Wang, Northwestern University, USA
Resetting the Epigenetic Balance of Polycomb/COMPASS Function for Cancer Therapy

Chuan He, University of Chicago, USA
Aberrant RNA Methylation in Human Cancers

Ulrike Litzenburger, Stanford University, USA
Short Talk: Direct Linkage of Cancer Cell Epigenomic State with Phenotype using Multi-Index Single-Cell ATAC-Seq

Coffee Break

Gideon Rechavi, Tel Aviv University, Israel
Cancer Epitranscriptomics

Brian J. Abraham, Whitehead Institute, USA
Short Talk: Three-Dimensional Gene Regulatory Landscapes in Normal and Cancer Cells

Michaela Frye, University of Cambridge, UK
RNA Post-Transcriptional m5C-Methylation in Stem Cells and Cancer

11:15 AM—5:00 PM
On Own for Lunch

11:15 AM—1:00 PM
Poster Setup

Breckenridge Ballroom
1:00—10:00 PM
Poster Viewing

Breckenridge Ballroom
4:30—5:00 PM
Coffee Available

Foyer
5:00—7:00 PM
Chromatin Assembly, Stem Cells and Aging
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Michaela Frye, University of Cambridge, UK

Robert E. Kingston, Massachusetts General Hospital, USA
Nucleosome Compaction and Polycomb-Group Repressive Function during Development

Anne Brunet, Stanford University, USA
Epigenetic and Metabolic Regulation of Aging and Rejuvenation

Ernesto Guccione, Institute of Molecular and Cell Biology, Singapore
Short Talk: Investigating the Function of PRDM Proteins in Stem Cells and Cancer

Johnathan R. Whetstine, Massachusetts General Hospital, USA
Epigenetics as a Gatekeeper to DNA Amplification

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
7:30—10:00 PM
Poster Session 2

Breckenridge Ballroom

TUESDAY, FEBRUARY 13

7:00—8:00 AM
Breakfast

Summit Gallery
8:00—11:15 AM
DNA (de)Methylation Dynamics and Cancer
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Kornelia Polyak, Dana-Farber Cancer Institute, Harvard Medical School, USA

Stephen B. Baylin, Johns Hopkins University School of Medicine, USA
DNA Methylation in Stem Cell and Cancer

Luisa Cimmino, New York University, USA
Short Talk: Restoration of TET Function as a Therapeutic Strategy in Leukemia

Peter A. Jones, Van Andel Research Institute, USA
Targeting Endogenous Retroviruses for Therapy

Coffee Break

Salvador Aznar Benitah, ICREA and Institute for Research in Biomedicine, Spain
Epigenetic Mechanisms in Adult Stem Cell Function, and their Impact over Mutational Burden of Cancer Stem Cells

Timothy C. Hallstrom, University of Minnesota, USA
Short Talk: UHRF2 Control of 5hmC Homeostasis and Differentiation in Retinal Progenitor Cells

Karen Adelman, Harvard Medical School, USA
Probing Transcription Regulation at Enhancers

11:15 AM—5:00 PM
On Own for Lunch

11:15 AM—1:00 PM
Poster Setup

Breckenridge Ballroom
1:00—10:00 PM
Poster Viewing

Breckenridge Ballroom
4:30—5:00 PM
Coffee Available

Foyer
5:00—7:00 PM
Connecting Noncoding RNAs and Cancer
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Salvador Aznar Benitah, ICREA and Institute for Research in Biomedicine, Spain

John L. Rinn, University of Colorado Boulder, USA
A Conserved TAD Boundary Organization at the Firre lncRNA Locus Is Resistant to Loss of Numerous CTCF Binding Sites

Chris Marine, VIB-KU Leuven, Belgium
(Patho-)Physiological Functions of the lncRNA NEAT1

Yotam Drier, MGH and Harvard Medical School, USA
Short Talk: Epigenetic Inhibition of CTCF Insulation in Cancer

Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Replication-Coupled Silencing and Spreading with RNAi

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
7:30—10:00 PM
Poster Session 3

Breckenridge Ballroom

WEDNESDAY, FEBRUARY 14

7:00—8:00 AM
Breakfast

Summit Gallery
8:00—11:15 AM
Novel Therapeutic Discoveries in Epigenetics I
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* John L. Rinn, University of Colorado Boulder, USA

Mark A. Dawson, Peter MacCallum Cancer Centre, Australia
Molecular Mechanisms Governing Sensitivity and Resistance to Epigenetic Therapies

Danette L. Daniels, Promega Corporation, USA
Short Talk: Understanding the Functional Pathway of BET Family Degradation Compounds

Kornelia Polyak, Dana-Farber Cancer Institute, Harvard Medical School, USA
KDM5B Links Cellular Transcriptome Heterogeneity to Therapy Resistance

Coffee Break

Robert MacLeod, Ionis Pharmaceuticals, Inc., USA
Next Generation Antisense Oligonucleotides as Therapeutic Inhibitors of LncRNAs for the Treatment of Cancer

Allison E. Drew, Epizyme, USA
Short Talk: Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma

Ronan C. O'Hagan, Merck Research Laboratories, USA
Epigenetics and Immune Modulation in Cancer

11:15 AM—5:00 PM
On Own for Lunch

2:00—4:30 PM
Workshop: Epigenetic Pathways and Cancer

Colorado Ballroom
* Tom Owen-Hughes, University of Dundee, Scotland

Giovanni Ciriello, University of Lausanne, Switzerland
The Landscape of Aberrant DNA Methylation across Human Cancers

Robert M. Witwicki, Dana-Farber Cancer Institute, USA
Novel Epigenetic Dependencies of Human Cancers

Noa Furth, Weizmann Institute of Science, Israel
Rewiring of Tumor Suppressors Networks: LATS Kinases and p53

Sandra Schick, CeMM GmbH, Austria
Loss of Specific Mammalian BAF Subunits Causes Global Changes in Chromatin Accessibility

Molly Christine Kingsley, University of Colorado, USA
The Role of H3K79 Methylation in IDH Mutant AML

Elisa Oricchio, École Polytechnique Fédérale de Lausanne, Switzerland
Oncogenic Mutation of EZH2 Inactivates Tumor- Suppressive TADs to Promote Lymphomagenesis

David I. Remillard, Harvard University, USA
Targeted Degradation of BRD9 as a Therapeutic Strategy in BAF-Dependent Cancers

Lingyan Jin, Genentech, Inc., USA
Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer

Beth Zucconi, Harvard Medical School, USA
Modulation of p300/CBP Activity by Small Molecules

4:30—5:00 PM
Coffee Available

Foyer
5:00—6:45 PM
Novel Therapeutic Discoveries in Epigenetics II
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
* Mark A. Dawson, Peter MacCallum Cancer Centre, Australia

Electron Kebebew, NCI, National Institutes of Health, USA
Targeting the Epigenome in Endocrine Cancers

Rab K. Prinjha, GlaxoSmithKline, UK
Epigenetic Targets for the Treatment of Human Diseases

James E. Bradner, Novartis Institutes for BioMedical Research, USA
Targeted Degradation of Chromatin-Associated Transcription Factors

6:45—7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 01/10/2018

Colorado Ballroom
7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
8:00—11:00 PM
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Breckenridge Ballroom

THURSDAY, FEBRUARY 15

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Cancer Research UK Cell Research
Incyte Corporation Merck & Co., Inc.
Novartis Institutes for BioMedical Research Pfizer Inc.
Roche
 

We gratefully acknowledge additional support from these exhibitors at this conference:

EpiCypher
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge additional support for this conference from:

Abcam plc

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Ionis Pharmaceuticals, Inc.


Merck & Co., Inc.


Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676