Sagebrush Inn & Suites Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Phosphoinositide Biology: New Therapeutic Targets Beyond Class I PI3K (B5)

Scientific Organizers: Emilio Hirsch, Tamas Balla and Cristina Donini


February 11—15, 2018

Sagebrush Inn & Suites, Taos, New Mexico, USA


Supported by the Directors' Fund


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Oct 10, 2017 [details]
Discounted Abstract Deadline: Oct 10, 2017 [details]
Abstract Deadline: Nov 8, 2017 [details]
Discounted Registration Deadline: Dec 12, 2017 [details]

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2018-B5 "Phosphoinositide Biology: New Therapeutic Targets Beyond Class I PI3K" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On October 10, 2017 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After October 10, 2017 until December 31, 2017 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
October 10, 2017 n/a
Discounted NON-STUDENT Registration
More details
Before and On December 12, 2017 820.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After December 12, 2017 1020.00 USD
Discounted STUDENT Registration
More details
Before and On December 12, 2017 595.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After December 12, 2017 795.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: October 10, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is November 8, 2017)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: October 10, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: November 8, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is October 10, 2017)

Discounted Registration Deadline: December 12, 2017

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 820.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 595.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1020.00 USD*
Student Registration Fee: 795.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 24 hr (international) time


The meeting will begin on Sunday, February 11 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 15 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 16 in order to fully experience the meeting.

SUNDAY, FEBRUARY 11

4:00—8:00 PM
Arrival and Registration

Sagebrush Lobby & Cantina
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Sagebrush Lobby & Cantina

MONDAY, FEBRUARY 12

7:00—8:00 AM
Breakfast

Sagebrush Lobby & Cantina
8:00—9:00 AM
Welcome and Keynote Address
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Emilio Hirsch, Fondazione per la Ricerca Biomedica – ONLUS, Italy

* Tamas Balla, NICHD, National Institutes of Health, USA

Pietro V. De Camilli, Yale University School of Medicine, USA
Phosphoinositide Signaling in the Control of Membrane Dynamics and Interactions

9:00—11:30 AM
Phosphoinositide Gradients and Lipid Transport at Membrane Contact Sites
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Gerry Hammond, University of Pittsburgh, USA

Bruno Antonny, Institut de Pharmacologie Moleculaire et Cellulaire, France
PI4P as an Energy Source for Cholesterol Transfer by OSBP through the Activity of two PI4-Kinases with Contrasting Membrane-Binding Properties

Coffee Break

Tamas Balla, NICHD, National Institutes of Health, USA
The Role of PI4KA in Controlling Membrane Lipid Dynamics

Jen Liou, University of Texas Southwestern Medical Center, USA
The Role of ER-PM Junctions in Phosphoinositide Homeostasis and Ca2+ Signaling

Raghu Padinjat, National Centre for Biological Sciences, India
Short Talk: Tuning of Lipid Transfer Reactions at Membrane Contact Sites in Drosophila Photoreceptors

Jana Humpolickova†, Institute of Organic Chemistry and Biochemistry, Czech Republic
Short Talk: Biophysical Determinants of Liposome-Reconstituted Lipid Transport by ORP5/ORP8

11:30 AM—5:00 PM
On Own for Lunch

11:30 AM—1:00 PM
Poster Setup

Chamisa Ballroom 2
1:00—10:00 PM
Poster Viewing

Chamisa Ballroom 2
4:30—5:00 PM
Coffee Available

Chamisa Lobby
5:00—7:00 PM
PI 4-Kinases as Possible Drug Targets
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Antonella De Matteis, Telethon Institute of Genetics and Medicine, Italy

Nihal Altan-Bonnet, NHLBI, National Institutes of Health, USA
Lipid Blueprints for Viral Replication and Transmission

Kasturi Haldar, University of Notre Dame, USA
Targeting a Mechanism of Artemisinin Resistance in Plasmodium falciparum Malaria

Cristina Donini, Medicines for Malaria Venture, Switzerland
MMV048, a Plasmodium PI4K Inhibitor as Potential Malarial Treatment

Radim Nencka†, IOCB Prague, Czech Republic
Short Talk: Phosphatidylinositol 4-Kinase IIIβ Inhibitors as Potential Therapeutics

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Chamisa Ballroom 2
7:30—10:00 PM
Poster Session 1

Chamisa Ballroom 2

TUESDAY, FEBRUARY 13

7:00—8:00 AM
Breakfast

Sagebrush Lobby & Cantina
8:00—11:15 AM
Inositide Phosphatases in Cancer and Development
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Amy Kiger, University of California, San Diego, USA

John D. York, Vanderbilt University, USA
Coordinated and Independent Biological Functions of Inositide Phosphatase Activities in Synaptojanins

Jeremy F. Reiter, University of California, San Francisco, USA
Cilia Have a Distinct Composition of Phosphoinositides and Other Lipids Critical for Signaling

Coffee Break

Christina Anne Mitchell, Monash University, Australia
Identification of Novel Roles for Inositol Polyphosphate 5-Phosphatases

Antonella De Matteis, Telethon Institute of Genetics and Medicine, Italy
The Phosphoinositides and the Golgi Complex

Gerry Hammond, University of Pittsburgh, USA
Short Talk: SAC1 Degrades its Lipid Substrate PtdIns4P in the Endoplasmic Reticulum to Maintain a Steep Chemical Gradient with Donor Membranes

Leonardo Salmena, University of Toronto, Canada
Short Talk: INPP4B-Associated Leukemic Stem Cell Self-Renewal as a New Target in AML therapy

11:15 AM—5:00 PM
On Own for Lunch

11:15 AM—1:00 PM
Poster Setup

Chamisa Ballroom 2
1:00—10:00 PM
Poster Viewing

Chamisa Ballroom 2
2:30—4:30 PM
Workshop: New and Emerging Paradigms and Possible Drug Targets

Chamisa Ballroom 1
* Cristina Donini, Medicines for Malaria Venture, Switzerland

Evzen Boura†, Institute of Organic Chemistry and Biochemistry, Czech Republic
Hijacking of PI4KB by Picornaviruses – Structural Insights and the Role of ACBD3

Igor Cestari†, Center for Infectious Disease Research, USA
Phosphatidylinositol Regulation of Antigenic Variation and Telomere Silencing in Trypanosomes

Brooke M. Emerling, Sanford Burnham Prebys Medical Discovery Institute, USA
Phosphatidylinositol-5-Phosphate 4-Kinases in the Control of Cellular Lipid Metabolism and Autophagy

Michael P. Sheetz, Mechanobiology Institute, National University of Singapore, Singapore
DNA Damage Causes Rapid Accumulation of Phosphoinositides for ATR Signaling

Carmen Sivakumaren, Harvard University, USA
Targeting the PIP4K2 Lipid Kinase Family in Cancer using Novel Covalent Inhibitors

Yoko Yoshikawa, Kobe University Graduate School of Medicine, Japan
Development of Anti-Cancer and Anti-Inflammatory Drugs Targeting Phospholipase Cε

4:30—5:00 PM
Coffee Available

Chamisa Lobby
5:00—7:15 PM
Structural Insights into Pharmacological Targeting of Lipid Kinases
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Evzen Boura, Institute of Organic Chemistry and Biochemistry, Czech Republic

John E. Burke, University of Victoria, Canada
Structural Basis of Regulation and Inhibition of Phosphatidylinositol 4-Kinase III Beta (PI4KIIIB)

Ujjini H. Manjunatha, Novartis Institute for Tropical Diseases, USA
Cryptosporidium Lipid Kinase Is a Promising Molecular Target to Treat Cryptosporidiosis

Roger L. Williams, Medical Research Council, UK
Structural Mechanisms of Regulation of the PI3K Superfamily

Chunmei Chang, University of California, Berkeley, USA
Short Talk: Rubicon Inhibits the PI3KC3 Complex II by Blocking a Membrane Docking Site

Raymond Blind, Vanderbilt University School of Medicine, USA
Short Talk: Intrinsic Kinase Auto-Regulation Mediated by Disordered Domains: Crystallographic and Enzyme Kinetic Analyses of the Human Inositol Polyphosphate Multikinase (IPMK)

7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Chamisa Ballroom 2
7:30—10:00 PM
Poster Session 2

Chamisa Ballroom 2

WEDNESDAY, FEBRUARY 14

7:00—8:00 AM
Breakfast

Sagebrush Lobby & Cantina
8:00—11:15 AM
Phosphoinositides Directing Trafficking for Degradation
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Volker Haucke, Leibniz Institut für Molekulare Pharmakologie, Germany

Lois S. Weisman, University of Michigan, USA
Multiple Mechanisms Dynamically Regulate the Signaling Lipid PI(3,5)P2

Haoxing Xu, University of Michigan, USA
Lipid Regulation of Lysosomal Ion Channels

Coffee Break

Mariella Vicinanza, Cambridge Institute for Medical Research, UK
PI(5)P Regulates Autophagy

Ankita Jaykumar, University of Texas Southwestern Medical Center, USA
Identifying Novel Functions of WNK1 Pathway in Autophagy

Benoit Bilanges, University College London, UK
Short Talk: Vps34 PI 3-Kinase Inactivation Enhances Insulin Sensitivity through Reprogramming of Mitochondrial Metabolism

Golam Saffi, Ryerson University, Canada
Short Talk: Lysosome Enlargement during PIKfyve Inhibition Occurs through Lysosome Coalescence Instead of Increased Biosynthesis

11:15 AM—5:00 PM
On Own for Lunch

11:15 AM—1:00 PM
Poster Setup

Chamisa Ballroom 2
1:00—10:00 PM
Poster Viewing

Chamisa Ballroom 2
4:30—5:00 PM
Coffee Available

Chamisa Lobby
5:00—7:15 PM
Monoinositide Phosphatases
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Lois S. Weisman, University of Michigan, USA

Volker Haucke, Leibniz Institut für Molekulare Pharmakologie, Germany
Phosphoinositide Conversion Directs Vesicular Trafficking

Jocelyn Laporte, Institute of Genetics and Molecular and Cellular Biology, France
Myotubularin Phosphoinositides Phosphatases Implication and Targeting in Neuromuscular Diseases

Amy Kiger, University of California, San Diego, USA
Coordination of Class II PI3-Kinase and Mtm PI3-Phosphatase Functions

Elizabeth A. Allen, University of Massachusetts Medical School, USA
Short Talk: Discovery of a Myotubularin-Related Phosphatase in Autophagy

Andrew T. Hale, Vanderbilt University School of Medicine, USA
Short Talk: Coordinated Inositide Lipid-Phosphatase Activities of Synaptojanin Modulate Actin Cytoskeleton Organization

7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Chamisa Ballroom 2
7:30—10:00 PM
Poster Session 3

Chamisa Ballroom 2

THURSDAY, FEBRUARY 15

7:00—8:00 AM
Breakfast

Sagebrush Lobby & Cantina
8:00—8:45 AM
Keynote Address
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Emilio Hirsch, Fondazione per la Ricerca Biomedica – ONLUS, Italy

Pier Paolo Pandolfi, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Novel Modes of PI3K Signaling Regulation and Deregulation in Disease Pathogenesis

8:45—11:30 AM
Beyond Class I PI 3-Kinases
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Lewis C. Cantley, Weill Cornell Medicine, USA

Emilio Hirsch, Fondazione per la Ricerca Biomedica – ONLUS, Italy
Class II PI3K Signaling in Cancer

Coffee Break

James Dowling, Hospital for Sick Children, Canada
3-Phosphoinositide Metabolism in Muscle Development, Muscle Disease and as a Therapeutic Target

Jonathan M. Backer, Albert Einstein College of Medicine, USA
PIK3CB Signaling in Breast Cancer

York Posor, University College London, UK
Short Talk: PI3K-C2α in dsRNA Sensing and Inflammation

Antonija Jurak Begonja, University of Rijeka, Croatia
Short Talk: PI3P Modulates Megakaryocyte Maturation and Platelet Production through Late Endosomes/Lysosomes

11:30 AM—5:00 PM
On Own for Lunch

4:30—5:00 PM
Coffee Available

Chamisa Lobby
5:00—6:45 PM
PIP Kinases as Emerging Drug Targets
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Pier Paolo Pandolfi, Beth Israel Deaconess Medical Center, Harvard Medical School, USA

Lewis C. Cantley, Weill Cornell Medicine, USA
Type 2 Phosphatidylinositol-5-Phosphate 4-Kinases in Cancer

Richard A. Anderson, University of Wisconsin Medical School, USA
Agonist-Stimulated PI3,4,5P3 Generation by Scaffolded Phosphoinositide Kinases

Atsuo T. Sasaki, University of Cincinnati, USA
PI5P4Kbeta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis

6:45—7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 01/11/2018

Chamisa Ballroom 1
* Tamas Balla, NICHD, National Institutes of Health, USA

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Chamisa Ballroom 2
8:00—11:00 PM
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Chamisa Ballroom 2

FRIDAY, FEBRUARY 16

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676