Keystone Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

NOTES:
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


This meeting is part of the Global Health Series

Download Flyer

Twitter hashtag for this meeting: #KSmicrobiome

Microbiome in Health and Disease (J8)

joint with the meeting on Inflammation-Driven Cancer: Mechanisms to Therapy (J7)

Scientific Organizers: Julie A. Segre, Ramnik Xavier and William Michael Dunne


February 5—9, 2017

Keystone Resort, Keystone, Colorado, USA


Sponsored by Intercept Pharmaceuticals, Inc., Merck & Co., Inc. and Novartis Institutes for BioMedical Research. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation.


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.

DEADLINES:
Global Health Travel Award Deadline: Sep 6, 2016 [details]
Scholarship Deadline: Oct 6, 2016 [details]
Discounted Abstract Deadline: Oct 6, 2016 [details]
Abstract Deadline: Nov 3, 2016 [details]
Discounted Registration Deadline: Dec 7, 2016 [details]

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2017-J8 "Microbiome in Health and Disease" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On October 6, 2016 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After October 6, 2016 until January 12, 2017 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
October 6, 2016 n/a
Discounted NON-STUDENT Registration
More details
Before and On December 7, 2016 795.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After December 7, 2016 945.00 USD
Discounted STUDENT Registration
More details
Before and On December 7, 2016 570.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After December 7, 2016 720.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: October 6, 2016


Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is November 3, 2016)

Global Health Travel Award Deadline: September 6, 2016


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: October 6, 2016


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: November 3, 2016


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is October 6, 2016)

Discounted Registration Deadline: December 7, 2016


Registration Fee: 795.00 USD* (includes 150.00 USD discount)
Student Registration Fee: 570.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 945.00 USD*
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 24 hr (international) time


The meeting will begin on Sunday, February 5 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 9 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, February 10 in order to fully experience the meeting.

SUNDAY, FEBRUARY 5

4:00—8:00 PM
Arrival and Registration

Longs Peak Foyer
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Longs Peak Foyer

MONDAY, FEBRUARY 6

7:00—8:00 AM
Breakfast

Colorado Rockies Ballroom
8:00—9:00 AM
Welcome and Keynote Address
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* William Michael Dunne, bioMérieux, Inc., USA

Sarkis K. Mazmanian, California Institute of Technology, USA
The Gut-Microbiome-Brain Connection in Neurological Diseases

8:00—9:00 AM
Welcome and Keynote Address
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Fiona M. Powrie, University of Oxford, UK

Lisa M. Coussens, Oregon Health & Science University, USA
Manipulating the Tumor Microenvironment in Cancer Therapy

9:00—11:15 AM
Monitoring Microbiome to Predict Disease Risk
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* William Michael Dunne, bioMérieux, Inc., USA

Ramnik Xavier, Massachusetts General Hospital and Broad Institute, USA
IBD, Crohn’s Microbiome

Coffee Break

Dan R. Littman, HHMI, New York University School of Medicine, USA
Regulation of T Cell Responses by Microbiota

Curtis C. Harris, NCI, National Institutes of Health, USA
Microbiome-TP53 Gene Interaction in Human Lung Cancer

9:00—11:30 AM
Inflammation-Driven Cancer
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Michael Karin, University of California, San Diego, USA

Fiona M. Powrie, University of Oxford, UK
Inflammation-Driven Cancer: Host and Microbial Pathways

Coffee Break

Mathias Florian Heikenwälder, German Cancer Research Center, DKFZ, Germany
On the Role of Immune Cells in NASH and NASH to HCC Transition

Arthur Kaser, University of Cambridge, UK
ER Stress and Colorectal Cancer

Jeonghyun Ahn, University of Miami, USA
Short Talk: The Role of STING in Suppressing Inflammation-Driven Intestinal Tumorigenesis

Matthias Ernst, Olivia Newton-John Cancer Research Institute, Australia
Short Talk: Excessive HCK Kinase Activity in the Tumor Stroma Polarizes Macrophages and Promotes Solid Malignancies

11:15 AM—12:30 PM
NIH Institutes’ Interests in Microbiome Research

Grays/Longs Peak
* Robert W. Karp, National Institutes of Health, USA

Ryan Ranallo, NIAID, National Institutes of Health, USA

Phil J. Daschner, NCI, National Institutes of Health, USA

Elisabet Caler, NHLBI, National Institutes of Health, USA

Ricardo Cibotti, NIAMS, National Institutes of Health, USA

Francesca Macchiarini, NIA, National Institutes of Health, USA

11:15 AM—1:00 PM
Poster Setup

Colorado Rockies Ballroom
12:30—5:00 PM
On Own for Lunch

1:00—10:00 PM
Poster Viewing

Colorado Rockies Ballroom
2:30—4:30 PM
Workshop 1: Microbiome in Health and Disease

Grays/Longs Peak
* Ami S. Bhatt, Stanford University, USA

Michael C. Abt, Sloan Kettering Institute, USA
Host Immune Response Supports Fecal Microbiota Transplant-Mediated Clearance of Clostridium Difficile Infection

Dingding An, Harvard Medical School, USA
Microbial Sphingolipids Modulate Host Epithelium Homeostasis and Disease

Naama Geva-Zatorsky, Harvard Medical School, USA
Gut Microbiota-Host Interactions and their Immune Modulations

Yun-Gi Kim, Keio University, Japan
Neonatal Acquisition of Clostridia Species Controls Colonization Resistance Against Bacterial Pathogens

Monica Viladomiu, Weill Cornell Medicine, USA
Functional Characterization of IgA-Targeted E. coli in Crohn's Disease-Associated Spondyloarthritis Links Mucosal Immunity with Systemic Inflammation

Xochitl Morgan, University of Otago, New Zealand
Gut Microbiota Acquisition in New Zealand Children in Relation to Early Life Exposures Including Probiotics: A Longitudinal Analysis

Ana Weil, Massachusetts General Hospital, USA
The Human Gut Microbiota and Susceptibility to Vibrio cholerae O1 Infection

2:30—4:30 PM
Workshop 1: Inflammation-Driven Cancer

Quandary Peak
* Mathias Florian Heikenwälder, German Cancer Research Center, DKFZ, Germany

* Hua E. Yu, Beckman Research Institute, City of Hope, USA

Ryan Kolb, University of Iowa, USA
IL-1beta promotes obesity-driven breast cancer progression through the upregulation of ANGPTL4 in adipocytes

Sarah McCuaig, University of Oxford, UK
Cytokine-Oncogene Synergies in Colorectal Cancer

Seyed Javad Moghaddam, University of Texas MD Anderson Cancer Center, USA
Muc5ac Plays an Essential Role in Promotion of K-ras Mutant Lung Cancer by Inflammation

Karen Pickering, Beatson Institute, UK
Guanine Nucleotide Exchange Factor Vav1 Promotes Survival in Colorectal Cancer through T-Cell Activation

Na-Young Song, NCI, National Institutes of Health, USA
Determining the Signaling Pathway of Epithelial-IKKalpha-Deletion-Mediated Symbiotic Bacterial and Fungal Infection in Carcinogenesis

Chunfeng Qu, Cancer Institute/Hospital, Chinese Academy of Medical Sciences, China
Liver Inflammatory Macrophages in Response to Hepatitis B Virus (HBV) Proteins Promote Hepatocellular Carcinoma by Enhancing Angiogenesis through IL23/IL23R Interaction

Martina Seiffert, German Cancer Research Center, Germany
Tumor Exosome-Derived Y RNA Activates TLR7/8 Signaling in Monocytes and Contributes to Cancer Inflammation and Immune Escape

4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:15 PM
Microbiome and Cancer (Joint)
Registered attendees can view abstracts starting on 01/05/2017

Longs/Grays Peak
* Arthur Kaser, University of Cambridge, UK

Laurence Zitvogel, Institut Gustave Roussy, France
Microbe-Driven Anti-Tumor Immunity

Giorgio Trinchieri, NCI, National Institutes of Health, USA
Role of the Microbiota in Inflammation, Carcinogenesis and Cancer Therapy

Curtis Huttenhower, Harvard School of Public Health, USA
Functional Analysis of Strains in the Human Gut Metatranscriptome

Cynthia L. Sears, Johns Hopkins University School of Medicine, USA
The Carcinogenic Potential of Bacterial Biofilms

7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
7:30—10:00 PM
Poster Session 1

Colorado Rockies Ballroom

TUESDAY, FEBRUARY 7

7:00—8:00 AM
Breakfast

Colorado Rockies Ballroom
8:00—11:00 AM
Complex Microbiome Analyses
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* Julie A. Segre, NHGRI, National Institutes of Health, USA

Rob Knight, University of California, San Diego, USA
Human Microbiome and Metabolome Dynamics

Eric J. Alm, Massachusetts Institute of Technology, USA
FMT Complex Analyses

Coffee Break

Michael A. Fischbach, University of California, San Francisco, USA
Small Molecules from the Human Microbiota

Katherine S. Pollard, University of California, San Francisco, USA
Decoding Cryptic Variation in the Human Microbiome

Kelly Wen Li Chen, Massachusetts Institute of Technology, USA
Short Talk: Integrated Gut/Liver Microphysiological System Elucidates Cytokine/Chemokine Inter-Tissue Crosstalk under Endotoxin-Induced Stress

8:00—11:15 AM
Inflammation and Cancer Stem Cells
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Owen J. Sansom, Beatson Institute of Cancer Research, UK

Florian R. Greten, Institute for Tumor Biology and Experimental Therapy, Germany
Stem Cells and Intestinal Tumorogenesis

Simon J. Leedham, University of Oxford, UK
Morphogen Signaling in Intestinal Inflammation and Carcinogenesis

Coffee Break

Fiona M. Watt, King's College London School of Medicine, UK
Contribution of Different Epidermal Cell Populations to Inflammation-Associated Cancers

Judith A. Varner, University of California, San Diego, USA
Talk Title to be Announced

Min-Kyung Choo, Massachusetts General Hospital/Harvard Medical School, USA
Short Talk: p38 MAPK Functions as a Tumor Suppressor in Skin Epithelial Cells, but as a Tumor Promoter in Myeloid Cells

Jelena Todoric, University of California, San Diego, USA
Short Talk: A Stress Activated p62-NRF2-MDM2 Axis Drives Pancreatic Tumorigenesis

11:00 AM—5:00 PM
On Own for Lunch

11:00 AM—1:00 PM
Poster Setup

Colorado Rockies Ballroom
1:00—10:00 PM
Poster Viewing

Colorado Rockies Ballroom
2:30—4:30 PM
Panel: The Integrative Human Microbiome Project (iHMP)
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple "omics" technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. The three iHMP projects have recently completed primary data generation and are entering an initial analysis phase, and this session will detail the data and resources made available to the research community by: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.

Grays/Longs Peak
Jennifer M. Fettweis, Virginia Commonwealth University, USA
Pregnancy and Preterm Birth

* Curtis Huttenhower, Harvard School of Public Health, USA
Inflammatory Bowel Disease

George M. Weinstock, The Jackson Laboratory, USA
Prediabetes

Anup Mahurkar, University of Maryland Baltimore, USA

2:30—4:30 PM
Workshop 2: Inflammation and Immunity Crosstalk

Quandary Peak
* Giorgio Trinchieri, NCI, National Institutes of Health, USA

* Laurence Zitvogel, Institut Gustave Roussy, France

Giuseppe Di Caro, University of California, San Diego, USA
Immunoglobulin A Attenuates Colonic Tumorigenesis by Controlling Microbial Translocation and Tumor-Elicited Inflammation

Ankit Malik, St Jude Children's Research Hospital, USA
IL-33 Regulates the IgA-Microbiota Axis to Restrain IL-1alpha Dependent Colitis and Tumorigenesis

Andrea Ponzetta, Humanitas Clinical and Research Center, Italy
Neutrophils are Protective in Cancerogenesis by Altering Tumor Microenvironment and Controlling Intestinal Microbiota

Sabine Waeber, Université de Lausanne, Switzerland
Mesenchymal Stem Cells from Human Squamous Cell Lung Carcinoma Modulate Natural Killer (NK) Cell Phenotype and Function

Martina Molgora, Humanitas Research Hospital, Italy
Interleukin-1 Receptor 8 (IL-1R8) Plays a Crucial Role in Natural Killer Cell Differentiation and Function

Venuprasad K. Poojary, Baylor Institute for Immunology Research, USA
A Novel Role for Itch in Inhibition of IL-17-Mediated Colon Inflammation and Tumorigenesis by ROR-gammat Ubiquitination

Christoph Andreas Reichel, Walter Brendel Centre of Experimental Medicine, Germany
Complex Formation of uPA and PAI-1 Promotes Myeloid Leukocyte Trafficking

4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:00 PM
Human Microbiome Studies
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* Ramnik Xavier, Massachusetts General Hospital and Broad Institute, USA

Andrew L. Goodman, Yale School of Medicine, USA
Cooperation and competition in the human gut microbiome

Julie A. Segre, NHGRI, National Institutes of Health, USA
Human Skin Microbiome: Topographic Functional Mapping of Healthy Volunteers and Patient Populations

Gary D. Wu, University of Pennsylvania School of Medicine, USA
Diet, the Gut Microbiome and Inflammatory Bowel Disease

Renuka Nayak, University of California, San Francisco, USA
Short Talk: Methotrexate Is an Antibacterial Drug Metabolized by Human Gut Bacteria

5:00—7:00 PM
Tumor-Elicited Inflammation
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Ming O. Li, Memorial Sloan-Kettering Cancer Center, USA

Yinling Hu, National Cancer Institute at Frederick, USA
IKKalpha, Autoimmunity and Chronic Fungal Infection in Esophageal and Skin Carcinogenesis

Hua E. Yu, Beckman Research Institute, City of Hope, USA
Stat 3 in Cancer Inflammation and as a Target in Cancer

Owen J. Sansom, Beatson Institute of Cancer Research, UK
Targeting Myeloid Cells in Epithelial Cancers

Elena Tosti, Albert Einstein College of Medicine, USA
Short Talk: MMR and Tgfb Signaling Cooperate in Suppressing Inflammation-Associated Colorectal Tumorigenesis

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
7:30—10:00 PM
Poster Session 2

Colorado Rockies Ballroom

WEDNESDAY, FEBRUARY 8

7:00—8:00 AM
Breakfast

Colorado Rockies Ballroom
8:00—11:00 AM
Genetic Diversity and Communication
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* Thaddeus S. Stappenbeck, Washington University School of Medicine, USA

Karen Guillemin, University of Oregon, USA
Modulation of Host Innate Immune Responses by Individual Microbiota Members

Eran Segal, Weizmann Institute of Science, Israel
Personalized Nutrition using Gut Microbiome and Clinical Data

Coffee Break

Robert E.W. Hancock, University of British Columbia, Canada
Network Biology Approaches to Understanding Inflammation

James M. Musser, Methodist Hospital Research Institute, USA
Integrative Approach to Investigating Human Pathogen – Host Interactions: A Nightmare of Genomic Diversity?

Mahesh S. Desai, Luxembourg Institute of Health, Luxembourg
Short Talk: A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

8:00—11:15 AM
Inflammation and Immunity Crosstalk I
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Shannon J. Turley, Genentech, Inc., USA

Michael Karin, University of California, San Diego, USA
Immune Crosstalk in Tumors

Alberto Mantovani, Humanitas University, Italy
Innate Immune Pathways and the Tumor Microenvironment

Coffee Break

Ming O. Li, Memorial Sloan-Kettering Cancer Center, USA
Immunity and Tolerance in Cancer

Toby Lawrence, INSERM, France
Mechanisms of Tumour-Associated Macrophage (TAM) Polarisation

Sven Brandau, University Duisburg-Essen, Germany
Short Talk: Absence of Endogenous Toll-Like Receptor Sensing Unleashes Protective Anti-Tumor Immunity and Tumor Regression

George Plitas, Memorial Sloan Kettering Cancer Center, USA
Short Talk: CD177 Identifies a Novel Subset of Regulatory T Cells (Treg) Infiltrating Human Breast Cancer

11:00 AM—5:00 PM
On Own for Lunch

11:00 AM—1:00 PM
Poster Setup

Colorado Rockies Ballroom
1:00—10:00 PM
Poster Viewing

Colorado Rockies Ballroom
4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:00 PM
Microbiome and Disease
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* Timothy K. Lu, Massachusetts Institute of Technology, USA

Thaddeus S. Stappenbeck, Washington University School of Medicine, USA
Microbial Metabolites that Modify Intestinal Wound Repair

Kathryn E. Holt, University of Melbourne, Australia
Klebsiella Pneumoniae and the Microbiome

Ami S. Bhatt, Stanford University, USA
Metagenomics and the Microbiome in Stem Cell Transplantation

Lindsay R. Kalan, University of Pennsylvania, USA
Short Talk: Multi-Kingdom Microbial Communities of Chronic Non-Healing Wounds and their Association with Clinical Outcomes

5:00—7:00 PM
Stromal Cells and the Tumor Microenvironment
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Alberto Mantovani, Humanitas University, Italy

Shannon J. Turley, Genentech, Inc., USA
Leukocyte Function and Positioning in Diverse Stromal Niches

Daniel L. Worthley, SAHMRI, Adelaide, Australia
Intestinal Mesenchyme in the Normal and Neoplastic Colon

Raghu Kalluri, University of Texas MD Anderson Cancer Center, USA
The Functional Role of Inflammation and Fibrosis in Pancreatic Cancer

7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
7:30—10:00 PM
Poster Session 3

Colorado Rockies Ballroom

THURSDAY, FEBRUARY 9

7:00—8:00 AM
Breakfast

Colorado Rockies Ballroom
8:00—11:00 AM
Molecular Discovery of Novel Antimicrobials
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* Sean F. Brady, Rockefeller University, USA

Gautam Dantas, Washington University School of Medicine, USA
Networks of Exchanging Antibiotic Resistance Between Commensal, Environmental, and Pathogenic Bacteria

William Michael Dunne, bioMérieux, Inc., USA
Next Generation Antimicrobial Susceptibility Testing

Coffee Break

Andreas Peschel, University of Tübingen, Germany
Staphylococcus Aureus in the Human Nose - A Facultative Pathogen's Interference with Microbiota

Silvio M. Vieira, Yale University, USA
Short Talk: A Gut Commensal Breaches Both Gut Lymphatic and Vascular Barriers to Drive Systemic Autoimmunity

Jonathan L. Linehan, NIAID, National Institutes of Health, USA
Short Talk: Cutaneous Commensal Bacteria Drive an Unconventional T Cell Response that Accelerates Wound Healing

8:00—11:00 AM
Inflammation and Immunity Crosstalk II
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Jane L. Grogan, Genentech, Inc., USA

Weiping Zou, University of Michigan, USA
Metabolic Control of Effector T Cells and Regulatory T Cells in Tumor

Thomas Gajewski, University of Chicago, USA
Host Factors Controlling Anti-Tumor Immunity: Unexpected Impact of the Commensal Microbiota

Coffee Break

E. John Wherry, University of Pennsylvania, USA
Molecular Basis of T Cell Exhaustion: Insights for Immunotherapy

Martin Oft, ARMO BioSciences, USA
PEGylated IL-10 induces Th1 and Th2 Immunity, Proliferation of PD1+ Lag-3+ CD8+ T Cells and Multiclonal T Cell Expansion in Cancer Patients

Bronislaw Pytowski, Eli Lilly, USA
Short Talk: The Effect of VEGFR2 Inhibition on Tumor Blood Vessels and Immune Landscape

11:00 AM—5:00 PM
On Own for Lunch

2:30—4:30 PM
Workshop 2: Metagenomic Analysis

Grays/Longs Peak
* Gautam Dantas, Washington University School of Medicine, USA

Michael G. Constantinides, NIAID, National Institutes of Health, USA
Mucosal-Associated Invariant T Cells Respond to Cutaneous Microbiota

Collin Edington, Massachusetts Institute of Technology, USA
Development of Bioreactor Devices for Microbiome and Multi-Organ Interaction Studies

Sho Kitamoto, University of MIchigan Medical School, USA
Gut Inflammation-Driven Metabolic Reprograming Regulates the Competitive Fitness of Pathogenic E. coli

David T. Riglar, Harvard Medical School, USA
Gut Feelings: Engineering Synthetic Bacterial Circuits to Functionally Probe the Mammalian Gut Microbiome

Neil Surana, Harvard Medical School, USA
Discovery of Disease-Modulating Microbiota Using Microbial Pedigree Analysis

2:30—4:30 PM
Workshop 3: Prevention and Therapy

Quandary Peak
* Carola H. Ries, Roche Innovation Center Munich, Germany

* E. John Wherry, University of Pennsylvania, USA

Eduardo Bonavita, Cancer Research UK Manchester Institute, University of Manchester, UK
COX-2 Expression Positively Associates with Tumor-Promoting Inflammatory Factors and Negatively with Anti-Tumor Immune Pathways in Human Cancer

David N. Brindley, University of Alberta, Canada
Blocking the Inflammatory Effects of Lysophosphatidate Signaling as a New Strategy for Decreasing Tumor Growth, Metastasis and Improving Chemotherapy

Feng Zhu, NCI, National Institutes of Health, USA
Fungal Infection and Immune Dysfunction Contribute to Esophageal Carcinogenesis

Kayla Knilans, NIAID, National Institutes of Health, USA
Type 2 Signaling Improves Survival and Reduces Tumor Growth in a Mouse Model of Colitis-Associated Cancer

Jeff Kwak, University of Colorado Denver, USA
Complement Activation Mediates Lung Cancer Progression and Metastasis through Alterations in CD4 T Lymphocytes

Max Wellenstein, Netherlands Cancer Institute, Netherlands
Loss of p53 Drives Systemic Neutrophilic Inflammation in Breast Cancer

4:30—5:00 PM
Coffee Available

Longs Peak Foyer
5:00—7:00 PM
Systems Microbiology
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
* Karen Guillemin, University of Oregon, USA

Timothy K. Lu, Massachusetts Institute of Technology, USA
Engineering the Microbiome

James Amos-Landgraf, University of Missouri, USA
Suppression of Tumor Growth using Biofilm Producing Sulfate-Reducing Bacteria in a Rat Model of Colon Cancer

Sean F. Brady, Rockefeller University, USA
Microbial Biosynthetic Diversity

Alexandra Zhernakova, University Medical Center Groningen, Netherlands
Short Talk: Interaction of Genetics and Food Intake Influences Gut Microbiota Composition

5:00—6:45 PM
Prevention and Therapy
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
* Thomas Gajewski, University of Chicago, USA

Carola H. Ries, Roche Innovation Center Munich, Germany
Combining Macrophage Targeting with Cancer Immunotherapies

Jane L. Grogan, Genentech, Inc., USA
The Inhibitory Immunoreceptor TIGIT Limits Anti-Tumor Immunity

Jen Morton, Cancer Research UK Beatson Institute, Scotland
Short Talk: Myeloid Cells as a Therapeutic Target in Pancreatic Cancer

Kristen M. Larsen, University of South Carolina, USA
Short Talk: The Role of Interleukin 33/ST2 Axis in Liver Metastasis of Colorectal Cancer

7:00—7:15 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 01/05/2017

Grays/Longs Peak
6:45—7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 01/05/2017

Quandary Peak
7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
8:15—11:00 PM
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Colorado Rockies Ballroom

FRIDAY, FEBRUARY 10

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bill & Melinda Gates Foundation Intercept Pharmaceuticals, Inc.
Merck & Co., Inc. Novartis Institutes for BioMedical Research

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Anaerobe Systems Diversigen
eLife Research Diets, Inc.
Seres Therapeutics
 

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



bioMérieux, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676