This meeting took place in 2012



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Complications of Diabetes: Mechanisms of Injury and Failure of Repair (C5)


Organizer(s) Rama Natarajan, Matthias Kretzler and E. Dale Abel
March 11—16, 2012
Boston Park Plaza • Boston, Massachusetts USA
Abstract Deadline: Nov 10, 2011
Late Abstract Deadline: Dec 14, 2011
Scholarship Deadline: Nov 10, 2011
Early Registration Deadline: Jan 12, 2012

Sponsored by Merck & Co., Inc.

Summary of Meeting:
Diabetes is associated with significantly accelerated rates of several microvascular and macrovascular complications including nephropathy, neuropathy, retinopathy and atherosclerosis. Furthermore, results from both clinical trials and animal studies indicate that these complications might progress despite glycemic control, a phenomenon termed metabolic memory. Ongoing studies have identified biochemical and nuclear mechanisms, genetic determinants, epigenetic factors and non-coding RNAs in the pathogenesis of diabetic complications. Thus, the study of the key mechanisms leading to injury in target organs and failure of adaptive processes holds great promise for the identification of mechanism-targeted therapeutic approaches. These experimental approaches have been aided by tremendous advances in high-throughput genomic and epigenomic technologies, integrated systems biology and bioinformatics. Advances in the fields of stem cell therapies, induced pluripotency and regenerative medicine have provided new hope for the treatment of complications. The goal of this interdisciplinary meeting is to integrate these evolving concepts with current knowledge to facilitate a systems-level understanding of diabetic complications.

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Scholarships/Awards

National Institute of General Medical Sciences (NIGMS) Ancillary Training Program Scholarship Recipients

Catrina Sims-Robinson
University of Michigan, USA

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/National Institute on Aging (NIA) Scholarship Recipients

Nancy E. Castro
City of Hope, USA

Paul M. Titchenell
University of Pennsylvania, USA

Zongwei Wang
Massachusetts General Hospital, USA

Adam R. Wende
University of Alabama at Birmingham, USA

The Barrie Hesp Scholarship on behalf of Ashley Rebecca Cukier Scholarship Recipients

Matthew P. Krause
Hospital for Sick Children, Canada

Subir Roy Chowdhury
St. Boniface Hospital Research Centre, Canada