This meeting took place in 2010

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Lymphocyte Activation and Gene Expression (B8)

Organizer(s) Leslie J. Berg, Lawrence E. Samelson and Facundo D. Batista
February 27—March 4, 2010
Beaver Run Resort • Breckenridge, Colorado USA
Abstract Deadline: Oct 27, 2009
Late Abstract Deadline: Nov 30, 2009
Scholarship Deadline: Oct 27, 2009
Early Registration Deadline: Dec 28, 2009

Sponsored by Amgen Inc., Genzyme Corporation and Novo Nordisk A/S

Summary of Meeting:
Lymphocytes mediate the adaptive immune responses to antigens derived from infectious agents, transformed cells, transplanted organs and, in the setting of autoimmunity, ones own cells. The study of lymphocyte activation and gene expression is central to understanding the complex biology of these cells and offers hope for regulating these cells in different clinical settings. Much has been learned in the past several decades in this field. Receptors, enzymes and adapter molecules have been identified, signaling cascades and networks have been defined, and the complex regulation of gene expression has been explored. Nonetheless many basic questions remain to be elucidated. Among several contentious areas of research that will be presented by experts at this meeting are the actual means by which antigen receptors initiate the activation process, how activation induces changes in signaling pathways, intracellular organelles and the cytoskeleton, and how changes in chromatin and transcriptional factors determine gene expression.

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KS/ABRCMS Travel Award Recipients

Christian Aguilera-Sandoval
University of California, Los Angeles, USA