Keystone Symposia
Home | My Account | Shopping Cart  0
  Advanced
     facebook  twitter
Meeting Details  Printer Version   Meeting Search   Contact Us

HIV Biology and Pathogenesis (A6)

Organizer(s): Thomas J. Hope, Katherine A. Jones and Daniel C. Douek
January 12 - 17, 2010
Santa Fe Community Convention Center  ·  Santa Fe, New Mexico
Abstract Deadline: September 16, 2009
Late Abstract Deadline: October 15, 2009
Scholarship Deadline: September 16, 2009
Early Registration Deadline: November 12, 2009


Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation. Sponsored by Gilead Sciences, Inc. and Sangamo BioSciences, Inc.



This meeting took place in the 2010 season.

Listed below are current meetings that are similar to this meeting in nature/content:

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
The Keystone Symposia Meeting on HIV Biology and Pathogenesis emphasizes key aspects of the basic virological, cell and molecular biological, and disease aspects of HIV. The focus will be to highlight recent advances in our understanding of HIV/AIDS ranging from the earliest events of transmission, to treatments for infected individuals, to interventions to prevent viral transmission. The goal of the meeting is to emphasize the basic mechanisms of viral replication and the interplay of the virus with the immune system leading to the development of AIDS.

Tuesday, January 12
3:00 - 7:30 PM Registration Sweeney Ballroom Foyer
6:30 - 7:30 PM Refreshments Sweeney Ballroom A-D
7:30 - 8:30 PM Keynote Address Sweeney Ballroom E-F
Stephen P. Goff, Columbia University
HIV-1 Interactions with Host Proteins
8:30 - 8:45 PM Orientation for New Attendees and New Investigators
Meeting Organizer, Dr. Thomas Hope, to lead discussion in a "What to Expect during your Attendance" for interested delegates.
Sweeney Ballroom E-F
Wednesday, January 13
7:00 - 8:00 AM Breakfast Sweeney Ballroom A-D
8:00 - 11:00 AM HIV Transmission and Early Pathogenesis Sweeney Ballroom E-F
* John P. Moore, Weill Medical College of Cornell University
Thomas J. Hope, Northwestern University, Feinberg School of Medicine
Defining the Mechanisms of HIV Entry and Interactions with the Female Genital Tract
Beatrice H. Hahn, University of Alabama at Birmingham
Natural History of SIVcpz in Wild Chimpanzees
Daniel C. Douek, NIAID, National Institutes of Health
Immune Aspects of HIV Disease Pathogenesis
Guido Silvestri, University of Pennsylvania School of Medicine
SIV Infection of Sooty Mangabeys
Jan Münch, University Clinic of Ulm
Short Talk: Testing the Effect of Semen on HIV Infection
9:20 - 9:40 AM Coffee Break Sweeney Ballroom A-D
11:00 AM - 1:00 PM Poster Setup Sweeney Ballroom A-D
11:00 AM - On Own for Lunch and Recreation
1:00 - 10:00 PM Poster Viewing Sweeney Ballroom A-D
2:30 - 4:30 PM Workshop 1: Interplay of Viral and Cellular Proteins Sweeney Ballroom E-F
* Paula M. Cannon, University of Southern California, Keck School of Medicine
* David McDonald, Case Western Reserve University
Hillel Haim, Dana-Farber Cancer Institute
An Inherent ‘Ligand-Reactivity’ Property of the HIV-1 Envelope Glycoproteins Determines both Fusion Capacity and General Inhibitor Sensitivity
Brian P. Doehle, University of Washington
HIV-1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells
Edward M. Campbell, Loyola University, Stritch School of Medicine
p62/Sequestosome1 Associates with and Stabilizes the Expression of TRIM5alpha Proteins
Jonathan Richard, Institut de Recherches Cliniques de Montréal
HIV-1 Vpr Promotes NK Cell-Mediated Killing by Upregulating Expression of Ligands for the Activating NKG2D Receptor
Amy J. Andrew, NIAID, National Institutes of Health
Functional Analysis of Bst-2/Tetherin Imposed Inhibition of HIV-1 Virus Release
Elena Chertova, National Cancer Institute, National Institutes of Health
Denying the Denialists: Purification of SIV Particles from Highly Viremic Monkey Plasma
Vincent Dussupt, NIAID, National Institutes of Health
Mutations of Basic Residues in the Nucleocapsid Region of HIV-1 Gag cause Budding Arrests
4:30 - 5:00 PM Coffee Available Sweeney Ballroom A-D
5:00 - 7:15 PM HIV Entry Sweeney Ballroom E-F
* Jeremy Luban, University of Geneva
Gregory B. Melikian, University of Maryland
Biophysics of HIV Entry
David McDonald, Case Western Reserve University
Cell Biology of HIV Trans-Infection
Anna Cereseto, Scuola Normale Superiore
Visualization of the Pre-Integration Complex
Benjamin Dale, Mount Sinai School of Medicine
Short Talk: The Virological Synapse Promotes HIV Entry into Fusion-Permissive Compartments
Andrea Polacchini-Oliveira Jordan, University of Pennsylvania School of Medicine
Short Talk: Pathological Correlates of Attenuation for SIVmac239 Containing a Mutation in a Tyr-Dependent Trafficking Motif in the Envelope Transmembrane Cytoplasmic Tail
7:15 - 8:15 PM Social Hour w/ Lite Bites Sweeney Ballroom A-D
7:30 - 10:00 PM Poster Session 1 Sweeney Ballroom A-D
Thursday, January 14
7:00 - 8:00 AM Breakfast Sweeney Ballroom A-D
8:00 - 11:00 AM Innate Restriction of HIV Infection Sweeney Ballroom E-F
* Wesley I. Sundquist, University of Utah School of Medicine
Michael H. Malim, King's College London School of Medicine
APOBEC3G and HIV-1 Vif
Jeremy Luban, University of Geneva
TRIM5 is a Receptor for Retroviral Capsid that Contributes to the Antiviral State
Paula M. Cannon, University of Southern California, Keck School of Medicine
Tetherin Restriction and its Ablation by Diverse Viral Proteins
Mark Yeager, The Scripps Research Institute
Structural Studies of HIV Capsid and TRIM5 alpha
Robert A. Barnitz, NIAID, National Institutes of Health
Short Talk: Protein Kinase A Phosphorylation Activates Vpr-induced Cell Cycle Arrest during HIV-1 Infection
9:20 - 9:40 AM Coffee Break Sweeney Ballroom A-D
11:00 AM - 1:00 PM Poster Setup Sweeney Ballroom A-D
11:00 AM - On Own for Lunch and Recreation
1:00 - 10:00 PM Poster Viewing Sweeney Ballroom A-D
2:30 - 4:30 PM Workshop 2: Towards Understanding How HIV Causes AIDS Sweeney Ballroom E-F
* Richard A. Koup, National Institutes of Health
* Galit Alter, Massachusetts General Hospital
Boris Dominik Jülg, Ragon Institute, Massachusetts General Hospital
Strong Antiviral CD8 T Cell Function in-vitro Correlates with Better Disease Outcome in HIV Elite Controllers Lacking Protective HLA Class I Alleles
Benjamin C. Chaon, University of Iowa
Simultaneous ex vivo Expression of the PD-1/PD-L1 Axis, a Potential Mediator of T-T Cell Interactions, Characterizes HIV-Specific CD4+ T Cells
Donald L. Sodora, Seattle Biomedical Research Institute
Double Negative T Cells (CD3+/CD4-/CD8-) with Potential CD4 T Cell Function during Natural SIV Infection of Sooty Mangabeys
Lena Al-Harthi, Rush University
CD4dimCD8bright T-Cells have Potent Anti-HIV-Specific Responses and their Phenotype is Induced in a beta-Catenin-Dependent Manner
Kelly M. Fahrbach, Northwestern University
Enhanced Cellular Responses and Environmental Sampling in Inner Foreskin Explants: Evidence for the Foreskin's Role in HIV Transmission
Victor H. Ferreira, McMaster University
The Effect of Co-Infection on HIV-1 Replication in the Female Genital Tract
Tara Edmonds, University of Alabama, Birmingham
Infectious Molecular Clones of Transmitted/Founder HIV-1 Infect Monocyte-Derived Macrophages Less Efficiently Than Highly Macrophage Tropic Viruses
Steven E. Bosinger, University of Pennsylvania
Global Genomic Analysis Reveals Rapid Control of a Robust Innate Response in SIV-Infected Sooty Mangabeys
4:30 - 5:00 PM Coffee Available Sweeney Ballroom A-D
5:00 - 7:15 PM Immune Responses to HIV Infection Sweeney Ballroom E-F
* Anna Aldovini, Children's Hospital Boston and Harvard Medical School
Galit Alter, Massachusetts General Hospital
NK Cells in HIV Infection
Richard A. Koup, National Institutes of Health
Interplay of HIV and the Immune Response
Timothy W. Schacker, University of Minnesota
Mechanisms of Lymphoid Tissue Fibrosis and he Subsequrnt Impact on in HIV Infection
Judith Angeline Briant, NIAID, National Institutes of Health
Short Talk: Are Infant African Green Monkeys Resistant to SIVagm Infection?
Leonid Margolis, National Institutes of Health
Short Talk: HIV Interactions with Other Viruses: And How to Exploit Them
7:15 - 8:00 PM Social Hour w/ Lite Bites Sweeney Ballroom A-D
7:30 - 10:00 PM Poster Session 2 Sweeney Ballroom A-D
Friday, January 15
7:00 - 8:00 AM Breakfast Sweeney Ballroom A-D
8:00 - 11:00 AM Regulation of HIV Integration and Gene Expression Sweeney Ballroom E-F
* Anna Cereseto, Scuola Normale Superiore
Frederic D. Bushman, University of Pennsylvania School of Medicine
HIV DNA Integration: Mechanism and Consequences
Peter P. Cherepanov, Imperial College London
Structural Basis for Retroviral PIC Assembly and Strand Transfer Inhibitor Action
Katherine A. Jones, The Salk Institute
Tat and Cellular Stress Induce the HIV-1 Core Promoter via Distinct Mechanisms
Qiang Zhou, University of California, Berkeley
Novel Cellular Cofactors and Mechanism for Tat-Activation of HIV-1 Transcription
Ivan D'Orso, University of California, San Francisco
Short Talk: Proteomic Study of HIV-host Transcription Complexes
9:20 - 9:40 AM Coffee Break Sweeney Ballroom A-D
11:00 AM - 1:00 PM Poster Setup Sweeney Ballroom A-D
11:00 AM - On Own for Lunch and Recreation
1:00 - 10:00 PM Poster Viewing Sweeney Ballroom A-D
1:30 - 4:30 PM NIAID Workshop: The Next Challenge: Elimination of HIV Reservoirs Sweeney Ballroom E-F
Janet Siliciano, Johns Hopkins University School of Medicine
Issues in HIV-1 Persistence and Latency
Carl H. June, University of Pennsylvania
Exploring the Potential of Gene Modified CD4 T Cells to Target the HIV-1 Reservoir
Olaf Kutsch, University of Alabama at Birmingham
HIV-1 Latency – Does Site of Integration Matter?
Vicente Planelles, University of Utah
The Role of NFAT in HIV-1 Latency: New Insights from a Central Memory T-Cell Model
Javier Martinez-Picado, ICREA & irsiCaixa Foundation
HIV-1 Replication and Immune Dynamics are Impacted by Raltegravir Intensification of HAART-Suppressed Patients
Sarah E. Palmer, Karolinska Institute
Characterizing Persistent HIV Viremia
Jeffrey C. Laurence, Weill Cornell Medical College
Proving the Concept: The First Well-Documented Functional, and Probably Complete, Case of HIV Eradication
* Diana Finzi, NIAID, National Institutes of Health
Wrap-Up and Discussion
* Janet Siliciano, Johns Hopkins University School of Medicine
Wrap Up and Discussion
2:45 - 3:15 PM Coffee Break Sweeney Ballroom A-D
4:30 - 5:00 PM Coffee Available Sweeney Ballroom A-D
5:00 - 7:00 PM Treatment and Prevention of HIV Infection Sweeney Ballroom E-F
* Dana H. Gabuzda, Dana Farber Cancer Institute
Steven G. Deeks, University of California, San Francisco
HIV-Association Inflammation as a Cause of Accelerated Aging
John P. Moore, Weill Medical College of Cornell University
Studying Entry Inhibitor-based Vaginal Microbicides in the Rhesus Macaque
Jerome H. Kim, Walter Reed Army Institute of Research
Understanding the Results of the Thai Vaccine Trial
Christopher Aiken, Vanderbilt University School of Medicine
Short Talk: Inhibition of HIV-1 Infection by Small Molecule Destabilization of the Viral Capsid
7:00 - 8:00 PM Social Hour w/ Lite Bites Sweeney Ballroom A-D
7:30 - 10:00 PM Poster Session 3 Sweeney Ballroom A-D
Saturday, January 16
7:00 - 8:00 AM Breakfast Sweeney Ballroom A-D
8:00 - 11:00 AM HIV Latency and Reservoirs Sweeney Ballroom E-F
* Vineet N. KewalRamani, NCI, National Institutes of Health
Eric M. Verdin, University of California, San Francisco
Epigenetic Regulation of HIV Latency
Anna Aldovini, Children's Hospital Boston and Harvard Medical School
Tat-mediated Gene Modulation in HIV Target Cells
Dana H. Gabuzda, Dana Farber Cancer Institute
NeuroAIDS and HIV Reservoirs
Bette T. Korber, Los Alamos National Laboratory
Transmission of HIV-1 and Dynamics of Early Escape from Cytotoxic T-Cells: with an Ultradeep View
Wendy Burgers, University of Cape Town
Short Talk: Immune Activation during Early HIV Infection Associates with the Rate of Disease Progression
9:20 - 9:40 AM Coffee Break Sweeney Ballroom A-D
11:00 AM - On Own for Lunch and Recreation
4:30 - 5:00 PM Coffee Available Sweeney Ballroom A-D
5:00 - 7:15 PM HIV Interactions with the Cell and Host Sweeney Ballroom E-F
* Michael H. Malim, King's College London School of Medicine
Frank Kirchhoff, University of Ulm
Role of Nef and Vpu in Primate Lentiviral Pathogenesis and Transmission
Wesley I. Sundquist, University of Utah School of Medicine
Hexameric Assemblies of a Restricting TRIM5Ą Protein: Implications for Molecular Recognition of Viral Capsids
Vineet N. KewalRamani, NCI, National Institutes of Health
Postentry Restriction of HIV-1 by a Capsid Interacting Factor
Marc C. Johnson, University of Missouri, Columbia
Short Talk: The Minimal Requirements for Viral Pseudotyping
Greg J. Towers, University College London
Short Talk: A Role for the Nuclear Pore Protein Nup358 (RANBP2) in Capsid Dependent Nuclear Entry of Lentiviruses
7:15 - 8:15 PM Social Hour w/ Lite Bites Sweeney Ballroom A-D
8:00 - 11:00 PM Entertainment Sweeney Ballroom A-D
Sunday, January 17
Departure
*Session Chair   †Speaker invited, not yet responded.



© 2010 Keystone Symposia on Molecular and Cellular Biology. All Rights Reserved.
Terms of Use | Privacy Policy | Site Map

Keystone Symposia is a 501(c)(3) non-profit organization directed and supported by the scientific community.

Phone: +1 (800) 253-0685 or +1 (970) 262-1230
Fax: +1 (970) 262-1525
info@keystonesymposia.org