| Sunday, May 18 |
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3:00 - 7:30 PM
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Registration
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INEC Conference Centre Foyer
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6:30 - 7:30 PM
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Refreshments
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INEC Conference Centre Foyer
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7:30 - 8:30 PM
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Keynote Address
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INEC Main Auditorium
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Brian K. Kobilka,
Stanford University
Structure and Dynamics of the Human beta 2 Adrenergic Receptor
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| Monday, May 19 |
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7:00 - 8:00 AM
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Breakfast
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INEC Conference Centre Foyer
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8:00 - 11:15 AM
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GPCR Conformation
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INEC Main Auditorium
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Jean-Philippe Pin,
Institute of Functional Genomics - CNRS/INSERM/Montpellier University 1&2
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Krzysztof Palczewski,
Case Western Reserve University
Structure of Rhodopsin
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Gebhard F. X. Schertler,
Paul Scherrer Institut
Structure of the Beta 1 Adrenergic Receptor: Progress in Obtaining Recombinant G Protein Coupled Receptor Structures
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Martin Caffrey,
University of Limerick
Membrane Protein Structure Determination Using Crystallography and Lipidic Mesophases
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Jonathan A. Javitch,
Columbia University
Dopamine D2 Receptors Form Higher Order Oligomers at Physiological Expression Levels
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Jean-Louis Banères,
Institut des Biomolécules Max Mousseron, UMR 5247 CNRS
Heterodimer Regulation of GPCR Activation
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9:20 - 9:40 AM
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Coffee Break
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INEC Conference Centre Foyer
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11:15 AM - 1:00 PM
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Poster Setup
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INEC Conference Centre Foyer
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11:15 AM -
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On Own for Lunch
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1:00 - 10:00 PM
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Poster Viewing
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INEC Conference Centre Foyer
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4:30 - 5:00 PM
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Coffee Available
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INEC Conference Centre Foyer
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5:00 - 7:15 PM
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Intracellular Signaling
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INEC Main Auditorium
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Jonathan A. Javitch,
Columbia University
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Xia Zhang,
University of Ottawa
Role of PTEN and 5-HT2c Receptor Coupling in Drug Abuse
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Lan Ma,
Fudan University
Beta-Arrestin and Synaptic Plasticity
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Joan Heller Brown,
University of California, San Diego
GPCR Regulation of Cell Proliferation
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Brigitte L. Kieffer,
IGBMC
A New Approach to Study GPCR Trafficking in vivo
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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INEC Conference Centre Foyer
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7:30 - 10:00 PM
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Poster Session 1
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INEC Conference Centre Foyer
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| Tuesday, May 20 |
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7:00 - 8:00 AM
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Breakfast
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INEC Conference Centre Foyer
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8:00 - 11:00 AM
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Interacting Proteins
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INEC Main Auditorium
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Joan Heller Brown,
University of California, San Diego
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John J.G. Tesmer,
University of Michigan
Structural Analysis of an Ancient Pathway Linking Gq-Coupled Receptors to RhoA
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Emiliana Borrelli,
University of California, Irvine
Specificity of Dopamine Mediated Signaling Differentially Directed by the Two D2 Receptor Isoforms
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Taroh Iiri,
University of Tokyo
Talk Title to be Determined
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Zoe Jade Barclay,
University of Edinburgh
Short Talk: Evidence for the Formation of a Functional Signaling Complex of the 5-HT2A Receptor with ARF1 and PLD1 and its Disruption in an H452Y Polymorphic Variant of the Receptor
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Dominique Massotte,
Institut de Génétique et de Biologie Moléculaire et Cellulaire
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9:20 - 9:40 AM
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Coffee Break
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INEC Conference Centre Foyer
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11:00 AM - 1:00 PM
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Poster Setup
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INEC Conference Centre Foyer
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11:00 AM -
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On Own for Lunch
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1:00 - 10:00 PM
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Poster Viewing
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INEC Conference Centre Foyer
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4:30 - 5:00 PM
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Coffee Available
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INEC Conference Centre Foyer
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5:00 - 7:00 PM
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Deorphanized GPCRs
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INEC Main Auditorium
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Olivier Civelli,
University of California, Irvine
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Frank Gannon,
Science Foundation Ireland
Welcome Remarks
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Stefan Offermanns,
Universität Heidelberg
Nicotinic Acid Receptor - Pharmacological and Physiological Functions
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Rainer K. Reinscheid,
University of California, Irvine
Neuropeptide S Modulates Arousal and Stress Responses
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Hans Bräuner-Osborne,
University of Copenhagen, Faculty of Pharmaceutical Sciences
Basic Amino Acid Receptor GPRC6A Uncovered
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Deborah Nguyen,
Genomics Institute of the Novartis Research Foundation
Short Talk: Utilizing High-Throughput Profiling to Identify Modulators of Novel GPCRs
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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INEC Conference Centre Foyer
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7:30 - 10:00 PM
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Poster Session 2
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INEC Conference Centre Foyer
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| Wednesday, May 21 |
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7:00 - 8:00 AM
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Breakfast
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INEC Conference Centre Foyer
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7:00 - 8:00 AM
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Poster Setup
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INEC Conference Centre Foyer
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8:00 - 11:15 AM
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GPCRs in Physiology 1
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INEC Main Auditorium
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Stefan Offermanns,
Universität Heidelberg
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Kenji Kangawa,
National Cardiovascular Center Research Institute
Ghrelin: Physiological Significance and Therapeutic Potential for Cardiovascular Diseases
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Mark J. Zoller,
Senomyx, Inc.
Using Sweet and Umami Taste Receptors to Discover Taste Enhancers
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William Henry Colledge,
University of Cambridge
GPR54 and Kisspeptins
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Shuh Narumiya,
Kyoto University
Physiology and Clinical Application of the Prostanoid Receptors
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Garret A. FitzGerald,
University of Pennsylvania
Prostaglandin Receptors in Cardiovascular Disease
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9:20 - 9:40 AM
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Coffee Break
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INEC Conference Centre Foyer
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11:15 AM - 12:00 PM
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Lunch
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INEC Conference Centre Foyer
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12:00 - 2:30 PM
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Poster Session 3
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INEC Conference Centre Foyer
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2:30 - 4:30 PM
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Workshop: Can Industry and Academic Scientists Cooperate to Facilitate Drug Discovery?
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INEC Main Auditorium
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P. Jeffrey Conn,
Vanderbilt University School of Medicine
A Model for Early Stage Drug Discovery in an Academic Setting
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Roy G. Smith,
Baylor College of Medicine
Growth Hormone Secretagogue Receptor
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Gerard J. Marek,
Abbott Laboratories
Academic-Industry Collaborations: An Industry Perspective
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Hugh Rosen,
The Scripps Research Institute
Chemical Probes not Drugs from Academia
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Bruce A. Posner,
Pfizer Inc.
The Pfizer-TSRI Collaboration: Partnering for Success in Early Lead Discovery
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4:30 - 5:00 PM
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Coffee Available
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INEC Conference Centre Foyer
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5:00 - 7:00 PM
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GPCRs in Physiology 2
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INEC Main Auditorium
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Brigitte L. Kieffer,
IGBMC
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Wylie W. Vale,
The Salk Institute
Corticotropin Releasing Factor Family of Ligands and their Receptors and Binding Protein
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Gilbert Vassart,
Université Libre de Bruxelles
Constitutive Activity of Wild Type GPCRs: Physiological and Evolutionary Significance
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Masayasu Kojima,
Kurume University
Phenotypic Analysis of Ghrelin Knockout Mouse
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Jean-Pierre Vilardaga,
Massachusetts General Hospital & Harvard Medical School
Short Talk: Conformational Cross-Talk between GPCR Heterodimers Controls Cell Signaling
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7:00 PM -
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On Own for Dinner
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| Thursday, May 22 |
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7:00 - 8:00 AM
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Breakfast
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INEC Conference Centre Foyer
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8:00 - 11:00 AM
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GPCRs in Preclinical Drug Programs
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INEC Main Auditorium
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Heidi E. Hamm,
Vanderbilt University School of Medicine
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Hugh Rosen,
The Scripps Research Institute
Under the Influence: S1P Receptor Therapeutics
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Timothy W. Lovenberg,
Johnson & Johnson Pharmaceutical Research and Development LLC
Relaxin 3 and Insulin 5 as Unique GPCR Agonists: Pharmacology and Preclinical Challenges
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Andrew D. Howard,
Merck Research Laboratories
GPCRs in Metabolism
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Colleen Marie Niswender,
Vanderbilt University
Allosteric Modulation of mGluR4 as a Novel Therapeutic Direction for the Treatment of Parkinson's Disease
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Katsutoshi Sasaki,
Kyowa Hakko Kirin Co., Ltd.
Short Talk: Reverse Chemical Genetics Approach Using a GPR4 Antagonist to Find a Novel Drug Candidate for Respiratory Diseases
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9:20 - 9:40 AM
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Coffee Break
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INEC Conference Centre Foyer
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11:00 AM -
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On Own for Lunch
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4:30 - 5:00 PM
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Coffee Available
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INEC Conference Centre Foyer
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5:00 - 7:00 PM
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Novel GPCR Drugs in the Clinic
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INEC Main Auditorium
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Vincent Mutel,
Addex Pharmaceuticals SA
Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Clinical Efficacy in Gastroesophageal Reflux Disease, Migraine and Acute Anticipatory Anxiety
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Gerard J. Marek,
Abbott Laboratories
Use of mGluR Allosteric Modulators in Schizophrenia
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Madhu Chintala,
Schering Plough Research Institute
PAR1 Antagonist
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Javier González-Maeso,
Mount Sinai School of Medicine
Short Talk: Identification of a Serotonin/Glutamate Receptor Complex Implicated in Psychosis
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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INEC Conference Centre Foyer
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8:00 - 11:00 PM
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Entertainment
|
INEC Conference Centre Foyer
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| Friday, May 23 |
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Departure
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